Báo cáo khoa học: "Increasing daily feeding occasions in restricted feeding strategies does not improve performance or well being of fattening pigs" pot

... purposes)Acta Veterinaria ScandinavicaOpen AccessResearchIncreasing daily feeding occasions in restricted feeding strategies does not improve performance or well being of fattening pigsEva Persson*1, ... frequently occurring competi-tion for feed in the treatment group. The present study does not support the use of increased feeding occasions in fattening pigs.Competing interestsThe authors declare ... times daily. This may be a consequence of more frequently occurring competition for feed in the treatmentgroup. The present study does not support increased daily feeding occasions in fattening...

báo cáo khoa học: ""I washed and fed my mother before going to school": Understanding the psychosocial well-being of children providing chronic care for adults affected by HIV/AIDS in Western Kenya" pdf

... to a more profoundunderstanding and knowledge of coping and well- being and provide us with a good starting point for movingtoward better health. Such an approach has been usefullytheorised ... movementtoward coping and well- being. Meanings ascribed tostressful life events have previously shown to be critical in coping and promoting psychosocial well- being [42,43]. In line with Antonovsky's ... mother before going to school": Understanding the psychosocial well- being of children providing chronic care for adults affected by HIV/AIDS in Western KenyaMorten Skovdal1 and Vincent...

Báo cáo khoa học: "Increasing N and P resorption efficiency and proficiency in northern deciduous hardwoods with decreasing foliar N and P concentrations" doc

... and insect damage.Litter sampling was coordinated with the peak of leafdrop for individual species and consisted in collectingfalling and recently fallen leaves. In order to reduce theerror ... perennials are supportedby our study. According to Killingbeck [16], the range of concentrations corresponding to ultimate potential re-sorption and completeresorption,the latter beingdefinedas the ... contradicting re-sults. In 1996, Killingbeck [16] introduced the concepts of nutrient resorption proficiency and ultimate potential re-sorption. These concepts offer an alternative measure of resorption...

báo cáo khoa học: "Increasing delivery of an outdoor journey intervention to people with stroke: A feasibility study involving five community rehabilitation teams" pps

... containing evidence of multiple outdoor journeysessions. Other outcomes of interest included the proportion of medical records that contained evidence of screening for outdoor journeys and driving ... reportedincreased walking capacity following four weeks of treadmill training and overground walking practice in community-dwelling stroke surv ivors with speed gains being maintained after three ... changes in practice were recorded (≥ 10% change) including b etterrecording and more frequent screening of people w ithstroke about their driving status (+ 24%), noting of: preferred modes of travel...

Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

... helicases. The binding sites for double-stranded RNA and ATP overlap, resulting in coupledbinding of both molecules. Simultaneous bindingforces the RNA into a bent conformation that isincompatible ... unwinding mechanism does not involve translocation, and nor does the ATP hydrolysiscorrelate with unwinding. High-resolution X-ray struc-tures have given insights into the mechanism(s) of DEAD-box ... startingpoints for invasion. The concerted process of opening of the initial double strand and the annealing of thenew duplex ﬁnally results in either the replacement of the original strand or the expulsion...

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... Uponbinding its ligands, dynamic conformational changes occur in both extra-cellular and intracellular domains of the receptor tyrosine kinases, resulting in the transphosphorylation of tyrosine ... stimulates intrinsic tyrosine kinase activity of the receptors and triggers autophosphorylation of speciﬁc tyrosine residues within the cytoplasmic regula-tory domain.These phosphorylated tyrosines ... activity because of substitutions in crucial residues in the tyrosine kinase domain. How-ever, it has many binding sites for p85, a regulatorysubunit of phosphatidylinositol 3-kinase, and thus...

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy doc

... compete with ATP for binding tothe tyrosine kinase pocket of the receptor, therebyinhibiting receptor tyrosine kinase activity and EGFRsignaling pathways (Fig. 1). Early clinical studiesshowed ... success of imatinib in the treatment of CMLprovided compelling evidence for the effectiveness of small-molecule tyrosine kinase inhibitors (TKIs) andtriggered the development of this class of agents ... EGFR mutations result in reposition-ing of critical residues surrounding theATP-binding cleft of the tyrosine kinasedomain of the receptor and thereby stabilizethe interaction with EGF-TKIs.Table...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

... domain is responsible for DNA binding speciﬁcityand dimerization, and the ligand-binding domain isresponsible for binding of the ligand and associatedinduced functions. The N-terminal region of ... AT-hook DNA-bindingdomains present in MLLs indicate that they mediatetargeting of MLLs to their nuclear site and permit spe-ciﬁc binding to the minor groove of AT-rich DNA [56].Deletion of AT-hook ... various coregulators, bind to the hormone responseelements present in the promoters of hormone-responsive genes leading to their gene activation. Usually proteins containing an LXXLLdomain interact...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf

... protein-binding platformfor several other proteins to initiate a fundamental cel-lular process. P-TEFb binds to the N-terminal portion of AF4, whereas the C-terminal portion of AF4 con-fers binding ... signaling viacompetitive binding to death receptors [45]. As men-tioned above, a second explanation is the inhibitoryeffect of mostly all GSK3 inhibitors against certainCDKs, including CDK9 ... the inactive DRB-sensitivity inducing factor (DSIF)protein and the inhibitory negative elongation factor(NELF) complex. Initial activation of this complexresults in short transcripts of ...

Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx

... points andstained for F-actin (red). The GFP intensity (represent-ing virus production) increased signiﬁcantly over time,as seen pictorially in Fig. 3A–E and in graphical form in Fig. 3F. Infection ... occur during the initial 6 h window of infection.We infected RPE cells with K26GFP [27], and stainedcells for F-actin, using phalloidin at 30 min and 6 hpostinfection, and examined the cells ... HS(data not shown). Thus it is likely that nectin-1 and ⁄ or HVEM could be important for HSV-1 entry into RPEcells.Nectin-1 acts as the major receptor for HSV-1entry into RPE cellsTo determine...

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