... bis-Cys31,Cys32-S-carboxyamidomethylated-BS-RNase;MAE, monomeric bis-Cys31,Cys32-S-aminoethylated-BS-RNase;MSSAE, monomeric bis-Cys31,Cys32-S-ethylamine-BS-RNase;MSSG, monomeric bis-Cys31,Cys32-S-glutathione-BS-RNase;CRI, ... cannot fit into the horseshoe cavity ofthe inhibitor, whereas a monomeric form of the enzymecan, and is fully inhibited by CRI. Indeed, monomericRNases lacking cytotoxic activity, such as bovine ... Gibco-LifeTechnology) supplemented with 10% fetal bovine serum(Gibco-Life Technology) and Penicillin-Streptomycin-Glu-tamine 1X (Gibco-Life Technology). Cell lines were main-tained at 37 °C in a humidified incubator...