Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment" pot
Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment" pot
... AccessResearch Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitmentHiroshi ... epithelial cells (HBEC)enhances the synthesis and release of a variety of pro-inflammatory cytokines and that supernatants from theseco-cultures instilled into rabbit lungs induces a systemicinflammatory ... cells aredirectly exposed to inhaled atmospheric particles thesesmall particles are phagocytized by both cells [10,12].Both cell types can synthesize a variety of pro-inflamma-tory cytokines...
- 12
- 251
- 0
Báo cáo y học: " Human T-cell leukemia virus type 2 Tax protein induces interleukin 2-independent growth in a T-cell line" ppt
... carried out the establishing the cell lines and the functional analysis of the cell lines. MO,FG, and MF participated in the experimental design, datainterpretation, and the writing of the manuscript.AcknowledgementsWe ... Tanaka Y, Gejyo F, FujiiM: PDZ domain-binding motif of human T -cell leukemiavirus type 1 Tax oncoprotein is essential for the interleukin2 independent growth induction of a T -cell line. Retrovirology2005, ... Treatment12320604080400CTLL-2Tax2B-312320604080400CTLL-2Tax2B-6CsA(-)CsA0.5ǴMCsA1.0ǴM12320604080400CTLL-2Tax2B-712320604080400CTLL-2Tax2B-812340206040800CTLL-2Tax1-212340802060400CTLL-2Tax1-6123100200400CTLL-2+IL-2Expression of Tax protein in transformed cellsFigure 2Expression of Tax protein in transformed cells. Cell lysates were prepared from the indicated cells, and the amounts of Tax proteins were...
- 7
- 239
- 0
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... clues to the mechanism underlying proteinstability at the amino-acid level. The molecular mechanismsunderlying protein maturation, folding, and stability in bacterial cytochromes c are beginning ... have gained insight into the molecularmechanisms underlying cytochrome c maturation and folding as well as stability. Bacterial cytochrome c hascontributed greatly to our understanding in these ... for the stability of HT c-552, and the corresponding regions in the wild-type PA c-551 and itsquintuple mutant. The mutated residues in the quintuple mutant, and the corresponding ones of the...
- 7
- 369
- 0
Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt
... in RA synoviocytesT cells and monocytes are two major cell types involved in RA pathogenesis. Some of their derived cytokines may bepresent at very low concentrations in the RA joint, and their ... membranewith monocytes/T cells, by the proliferation of synovial liningcells and by the production of proinflammatory cytokines,which contribute to cartilage and bone destruction.Recent therapeutic interventions ... necrosisfactor alpha (TNF-α) and IL-1 inhibitors strongly support the importance of cytokines in RA. These cytokines arekey activators of the TFs AP-1, Egr-1 and NF-κB. Bindingsites for these TFs...
- 9
- 414
- 0
Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps
... scaffold to bring the two B progenitor cells into close proximity of the T cell to allowcytokine eavesdropping. The model outlined in Fig. 7 bears some resemblance to otherpublished models of spreading ... (sIg) binds to and processes the determinant and displays the resulting epitopes to T cells in the context of MHC II and accessory proteins in a typical immune synapse.Figure 7A scaffolding model ... sort of T cell cytokine activation of progen-itor B cells 'cis' activation to indicate that the activation is to aprogenitor B cell displaying sIg directly in close proximity to aT cell...
- 15
- 413
- 0
Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps
... 3b).As inflammatory cytokines are thought to play a critical role in the pathogenesis of RA, we monitored the production of the proinfammatory cytokines TNF-α, IL-1β, and INF-γ as well asanti-inflammatory ... and INF-γ fromisolated spleen cells induced by LPS. As the involvement of each of these cytokines in the pathogenesis of arthritis is wellFigure 5Steady state mRNA levels of the inflammatory ... in the Indian Ayurvedic system of medicine[20,21]. Given the potential role of PPARγ in inflammatoryprocesses, we hypothesized that THR0921 may have protec-tive effects in a murine model of...
- 8
- 339
- 0
Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx
... of the innate immune systemas their cardinal feature. While the intracellular functions of alarmins vary, in their extracellular form, they function as pro-inflammatory mediators to alert the ... functions in vivo to enhance inflammation bybinding PAMPs, DAMPs, and cytokines to promote dual-receptor interactions that may be especially effective because of their proximity. These receptors include ... system to tissuedamage and to trigger an immediate response. A key facet of the biology of alarmins is therefore their translocation from the inside to the outside of the cell [1].During the...
- 10
- 384
- 0
Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... National Institute of Allergy and Infectious Diseases (NIAID) due to its ability to initiate infec-tion via aerosol contact; the rapid onset of sepsis following the development of symptoms and the ... lineage,together with under expression of transcripts related to T-cells, B-cells, and cytotoxic cells, indicated substantial dys-regulation of the host immune system in response to infection in ... indicated by a spot, with the intensity of the spot representing the proportion of significantly differentially expressed transcripts for each one of the transcriptional modules. The color of the spot...
- 22
- 395
- 0
Báo cáo y học: " Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats" pps
... studies, and performed the Western blotting analysis. YJL and ICC participated in the interpretation of data and performed the statistical analysis. JCY conceived of the study, designed and coordinated ... previously [12]. In brief, abolus intraveno us injection of phenylephrine (10 μg/kg)was administered to evoke the BRR before and 10, 30 or60 min after microinjection of the test agent into NTS. The ... underlying the enhancement of BRR response by ADM in NTS. AC:adenylate cyclase; ADM: adrenomedullin; ADMR: adrenomedullinreceptor; GC: guanylate cyclase; Gs: stimulatory GTP-binding protein;nNOS:...
- 9
- 633
- 0
Báo cáo y học: " Non infective severe aortic paravalvular leakage 7 years after surgery: the role of suture technique" pot
... of PVL of only 2.3% and Qicai [5] surprisingly0%. The advantages of the semicontinuous suture t ech-nique may consist in a shorter CPB, in a reduced myo-cardial ischemic injury time, and in ... non coronary aortic sinus, due to the semicontinuous suture breaking (Figure 2). The othertwo sutures of the left and right coronary sinuses wereintact. After the prosthesis explant, a new ... According to a “parachutetechnique” the sutures were suspended (left loose) to enable an easier suturing of the aortic annulus and sew-ing ring of the artificial valve prior to lower the prosthe-sis....
- 3
- 321
- 0
Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015MÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ