Báo cáo y học: "Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction" ppt
Báo cáo y học: "Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis" potx
... to day 3 in the spleen. Increases of the corresponding proteins were significant in comparison with day 0 only in the case of IL-2 (day 6). By day6 (transition to the chronic phase), the mRNA ... for any cytokine in anyorgan at any time point.Discussion The present study documents that, in AIA, elevation of IL-1β in the SM as well as elevations of IL-6 mRNA in SM,inguinal LN, and spleen ... by immunohistochemistry in the respective mousemodel [21].Figure 3Expression of proteins for various cytokines in the synovial membrane of rats with AIAExpression of proteins for various cytokines...
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Báo cáo y học: "Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints" potx
... effects of inhibiting or stabilizing hypoxia-inducible factor (HIF)-1α by 2-methoxyestradiol ordimethyloxaloylglycine on the progression of osteoarthritis in murine knee joints.Methods 2-Methoxyestradiol ... IL-6.Conclusions Induction of osteoarthritis by 2-methoxyestradioldemonstrates the importance of HIF-1 in maintaining the integrity of hypoxic articular cartilage. Stabilization of HIF-1 bydimethyloxaloylglycine, ... dimethyloxaloylglycineEffects of 2-methoxyestradiol and dimethyloxaloylglycine. Effects on synovial tissue, levels of hypoxia-inducible factor (HIF) 1α and viability of chondrocytes, and the effect...
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Báo cáo y học: "Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study" ppt
... in identical twins. J Bone Joint Surg Br 1 959 , 41:314-318.11. Mabuchi A, Nakamura S, Takatori Y, Ikegawa S: Familial osteoar-thritis of the hip joint associated with acetabular dysplasia maps to ... Nishida K, Furuichi T, Toki H, Nishimura G, KawabataH, Yokoyama H, Yoshida A, Tominaga S, Nagano J, Shimizu A, Wakana S, Gondo Y, Noda T, Shiroishi T, Ikegawa S: A noveldominant-negative mutation ... Iuchi Y, Takagi M, OginoT: Developmental failure of the intra-articular ligaments in mice with absence of growth differentiation factor 5. Osteoar-thritis Cartilage 2007, 15: 468-474. 15. Masuya...
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Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx
... 18:11http://www.jbiomedsci.com/content/18/1/11Page 6 of 10 low taurine concentrations ≤ 10-7M. Therefore, the neuronal pathway involved in acid secretion induced bylow taurine concentrations may predominantly involve in ... presence of taurine- containing c ells and taurine- induced acid secretion in the stomach. In the body of the stomach, taurine- immunoreactive cells wereobserved along the l ength of the mucosal ... cholinergic neurons. Both TTX and atropine comple-tely inhibited the acid secretion induced by lo w concen-trations of taurine (10-7M and under). In contrast,there t wo components in the acid...
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Báo cáo y học: " Role of miR-1 and miR-133a in myocardial ischemic postconditioning" pptx
... subsequent myocardial injury, in which apoptosis may play a key role in myocardial IR injury [2]. It is therefore important tofind the end ogenous protective mechanism against apop-tosis induced by myocardial ... miR-13 3a, and decrease apoptosis of cardiomyocyte. Myocardial- specific miR-1 and miR-13 3amay play an important role in IPost protection by regulating apoptosis-related genes. MiR-13 3a may attenuateapoptosis ... neonatalcardiomyocytes and myocardium before they were treated with IR. The effect of miRNAs on apoptosis wasdetermined by flow cytometry and TUNEL assay. CASP9, as one of the candidate target of miR-13 3a,...
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Báo cáo y học: " Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin" potx
... bleomycin6 in bleomycin6 in bleomycin6 in bleomycin- -induced lung induced lung induced lung induced lung inflammatory changes in mice inflammatory changes in miceinflammatory changes in mice inflammatory ... bleomycinbleomycinbleomycinbleomycin- -induced pulmonary inflammation in the ratinduced pulmonary inflammation in the ratinduced pulmonary inflammation in the ratinduced pulmonary inflammation in the ... CCAAT/enhancer binding protein beta in bleomycinCCAAT/enhancer binding protein beta in bleomycinCCAAT/enhancer binding protein beta in bleomycinCCAAT/enhancer binding protein beta in bleomycin- -induced...
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Báo cáo y học: " Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation" docx
... pro-inflammatoryagents. Inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and increased tachykinin levels are ... [11]. The tachykinins, substance P and neurokinin A, arepresent in sensory afferent nerves and inflammatory cells in the airways. They may be released by a variety of stimuli(e.g. cigarette ... neurogenic inflammation in the airways [21].Furthermore, cigarette smoke-induced airway neu-trophilia was attenuated by a dual tachykinin NK1/NK2 receptor antagonist in guinea pigs [22]. The purpose...
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Báo cáo y học: " Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma" potx
... that LPA regulates airway inflammation via stimulating the release of cytokines and inflammatorymediators that modulate infiltration of neutrophils andeosinophils into the airway, others point ... structural changes of the airway in asthma by recruiting, activating and promoting inflam-matory cells into the airway [38-40]. In addition tocytokines, lipid mediators such as prostaglandins, ... mortality [29]. These studies suggest a role for LPAreceptors in linking lung injury in the murine bleomycin model of pulmonary fibrosis.Asthma is a chronic inflammatory disease of the airwaysinvolving...
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Báo cáo y học: "Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle " pdf
... sensitization of murine bronchial smooth muscleFigure 2Acetylcholine (ACh)-induced Ca2+ sensitization of murine bronchial smooth muscle. (A) A typical recording of contraction induced by ... tounderstand changes in the contractile signaling of airway smooth muscle cells associated with the disease. Smooth muscle contraction including airways is mainlyregulated by an increase in cytosolic Ca2+ ... contractile sig-naling in smooth muscle, it has been demonstrated thatagonist stimulation increases myofilament Ca2+ sensitiv-ity in various types of smooth muscles including airways[8,10,21,31]....
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Báo cáo y học: "Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction" ppt
... factor-induced contraction are still unknown. In this study we investigated the role of contractile prostaglandins and Rho-kinase in growth factor-induced ASM contraction.Methods: Growth factor-induced ... subsequentactivation of Rho-kinase. Therefore, we investigated theeffects of inhibition of Rho-kinase, MEK and cyclooxyge-nase (COX) on growth factor-induced prostaglandin-pro-duction and contraction, using ... dependent on Rho-kinase, MAPK and COX. Interestingly, growth factor-induced PGF2α -and PGE2-release from tracheal ringswas significantly reduced by U-0126 and indomethacin, but not by Y- 27632....
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Báo cáo y học: " Role of the Fas/FasL Pathway in HIV or SIV Disease" ppsx
... pathogen-esis of HIV/ AIDS.Significance of indirect cell killing for HIV vaccine/therapeutics designKnowing the role for uninfected bystander cell killing in disease has not resolved the challenge of ... sparing the fraction of infected cells. Such a process will tend to increase the pro-portion of infected cells and diminish the proportion of uninfected cells in a tissue heavily burdened by SIV ... applying thisinformation to treating HIV in man. An anti-Fas treatmentduring acute infection would be difficult to deliver. Sinceit may not modulate vRNA, the main marker for HIV ther-apy,...
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Báo cáo y học: " Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses" ppt
... CentralPage 1 of 11(page number not for citation purposes)RetrovirologyOpen AccessResearch Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic ... containing syncytia in response to focal areas of virus infected cells. Plates were fixed and stained 3 dayslater and examined for plaques of syncytia. Syncytium formation and inhibitors of N-linked ... cyto-pathic and/ or infectious in the transfectants.Effect of glycosylation inhibitors on cellular proteins involved in virus entryThe glycosylation inhibitor tunicamycin (Tu) was previ-ously shown...
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Báo cáo y học: " Role of common human TRIM5α variants in HIV-1 disease progression" ppsx
... and intron-exonAssociation of human TRIM5α haplotypes with HIV-1 disease progression in vivoFigure 3Association of human TRIM5α haplotypes with HIV-1 disease progression in vivo. Panel A, Inferred ... (Gibco-Invitro-Restriction of HIV-1 by common human TRIM5α variantsFigure 2Restriction of HIV-1 by common human TRIM5α var-iants. HeLa cells were stably transduced by oncoretroviral vectors expressing the Rhesus ... haplotypes car-rying non-synonymous variants. Panel B, Analysis of haplotypes according to the most parsimonious evolutionary analysis, where two main huTRIM5α groups can be defined according...
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Báo cáo y học: "Role of selective V2-receptor-antagonism in septic shock: a randomized, controlled, experimental study" pot
... ST each) without significant differencesamong groups.Laboratory variables of organ function and argininevasopressin plasma levelsAlanine aminotransferas e and aspartate aminotransferaseactivity ... placebo;cP < 0.05 versus baseline; n = 7 each. ALT, alanine aminotransferase; AST, aspartate aminotransferase; AVP,arginine vasopressin.Figure 3 Arterial base excess (a) and arterial lactate ... thaninfus ion of placebo and AVP in restoring cardiovascularand renal functions in early ovine septic shock. Open-label norepinephrine was additionally titrated to main-tain mean arterial...
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Báo cáo y học: " Diagnosis of invasive bronchial-pulmonary aspergillosis in patients with chronic obstructive respiratory diseases" pptx
... Treatment of Cancer/National Institute of Allergy and Infectious Diseases Mycoses Study Group; IBPA, invasive bronchial-pulmonary aspergillosis; IPA, invasive pulmonary aspergillosis. Competing interestsThe ... Central Ltd Diagnosis of invasive bronchial-pulmonary aspergillosis in patients with chronic obstructive respiratory diseasesPierre Bulpa* and Alain DiveSee related research by He et al., ... limits the possibility of collecting histological evidence of IPA. In a recent study with the largest series of IPA in patients with chronic obstructive pulmonary disease, none of the 53 cases...
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Từ khóa: báo cáo khoa học y họcbáo cáo y họcbáo cáo y học cổ truyềnbáo cáo y tế học đườngmẫu báo cáo y tế học đườngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ