Báo cáo khoa học: "Molecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniae using cDNA microarrays" doc

Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt

... existing in faeces from the skunk silkworm, Bombyx mori. J Sericult Sci Japan 47, 161–165.6 Inokuchi T & Yoshitake N (1978) Abnormality of amino acid metabolism in the mutant -skunk of the K. ... acts in the third step of leucine degradation and the sku mutant accumulates branched-chain amino acids in haemolymph, this mutant may be useful in the investigation of unique branched-chain aminoacid ... cDNAsequences using the RACE method in both strainsrevealed the presence of a single point mutation in 1337 nucleotides of BmIVD. In the sku mutant, the 1127th guanine from the start codon was...

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

... various chemokines stimu-lated mainly by in ammatory cytokines, including IL-1b, TNF-a andIFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning ... subclasses include the CC chemokines (where the cysteines are neighboring) and the CXC chemokines (where the cysteines are separated by oneamino acid). The CXC chemokines mainly act on neu-trophils ... caninduce autocrine ⁄ paracrine stimulation of these cells, leading tojoint destruction. Chemokines in the joints of patients T. Iwamoto et al.4450 FEBS Journal 275 (2008) 4448–4455 ª 2008 The Authors...

Báo cáo khoa học: Molecular mechanisms of the phospho-dependent prolyl cis ⁄ trans isomerase Pin1 docx

... destabilizing the double bond character of the pThr-Pro bond [26].Further evidence is available for the catalytic mecha-nism of Pin1 resembling more closely that of the other prolyl cis ⁄ trans isomerases, ... molecular mechanisms of the enzyme action. Most importantly,we want to critically review the evidence that Pin1 would or would not act as a prolyl cis ⁄ trans isomerase. Molecular mechanisms of Pin1 ... dependence of Pin1, be it for binding or for prolyl cis trans isomerization,therefore await further structural elucidation.Structural features of Pin1 substratesConcerning the function of Pin1, ...

Báo cáo khoa học: Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis Functional analysis of the promoter identiﬁes a calcium sensitive region required for basal activity doc

... Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis Functional analysis of the promoter identiﬁes a calcium sensitive region required for basal activity Natercia Conceic a o1, ... 5Â-CGGGATCCCAATCTGTTGCTAATTAGG-3Â)andthe3Â specic oligonucleotides (5Â-GAAGATCTACCACACCTCCTCATCTCC-3Â) for ampli-cation of the region from )180 to )36 and (5Â-GAAGATCTAACTAGATTTTACCATTGG-3Â) for amplication of the region from ... three copies of double stranded oligonucleotidesspanning the region from )70 to )36 of t he xMGP promoter (5Â-GATCCAGGGGAGGGAAAACAAGGAGATGAGGAGGTGTGGT-3Â,and5Â-GATCTACCACACCTCCTCATCTCCTTGTTTTCCCTCCCCTG-3Â)as...

Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc

... structures of the wild-type, single- and double-mutant EhPGKs in aclosed conformation will certainly help to clarify the molecular arrangement in the guanine ring binding siteduring the binding of ... kinase gene for the correspondingamino acid residues present in the adenine nucleotide-dependent phospho-glycerate kinases and the recombinant proteins were puriﬁed. Kinetic anal-ysis of the ... and Val341 (patch C). The corresponding reported amino acid residuesinvolved in adenine binding in the other crystallizedproteins, as well as in the EhPGK identiﬁed in the predicted model, were...

Báo cáo khoa học: Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation pdf

... 2007 The Authors Journal compilation ª 2007 FEBS Molecular dynamics of the DNA- binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation M. ... the deformability required for the formation of the Early protein 2 C-terminal DNA- binding domain DNA complexes of var-ious types is based not only on the rigidity of the base sequences in the DNA ... characterize the two proteins, together with the different structural andconformational features of the spacer regions in the DNA target sequences, indicate diverse mechanisms for the recognition of the...

Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc

... Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis Roxane ... by the cell envelope of M. tuberculosis and to virulence [3–6]. Nevertheless, their precise molecular mechanisms of action are still unknown, and the speci-ﬁc roles of the various members of the ... strain were present in the spleen of these mice. For the determination of the number of PMM56 bacteria present in the spleen of these four mice, we thus chose avalue of 50 CFU per spleen. The...

Báo cáo khoa học: Molecular cloning of the ecdysone receptor and the retinoid X receptor from the scorpion Liocheles australasiae pot

... 2007)doi:10.1111/j.1742-4658.2007.06139 .x cDNAs of the ecdysone receptor and the retinoid X receptor were cloned from the Japanese scorpion Liocheles australasiae, and the amino acidsequences were deduced. The full-length ... acids. The amino acid sequence of the L. australasiae ecdysone receptor was similar to that of the ecdysone receptor- A of the soft tick, Ornithodoros moubata (68%) and to that of the ecdysone receptor- A1 ... Liocheles australasiae ecdysone receptor; LaEcR-A, Liocheles australasiae ecdysone receptor A-isoform; LaRXR, Liocheles australasiae retinoid X receptor; PonA, ponasterone A;RXR, retinoid X receptor; ...

Báo cáo khoa học: Molecular analysis of the interaction between cardosin A and phospholipase Da Identiﬁcation of RGD/KGE sequences as binding motifs for C2 domains pdf

... Taken together our results indicate that the C2 domain of plant phospholipase Da can act as a cardosin A- binding domain and suggest that plant C2 domains may have an additional role as RGD ⁄ KGE-recognition ... of both motifs and in particular their basic residues was fur-ther emphasized by the complete lack of interaction between the C2 domain and the double mutated(AGD ⁄ AGE) cardosin A. The docking ... -trans-ferase-fused phospholipase Da constructs were performed. Results revealedthat the C2 domain of phospholipase Da contains the cardosin A- binding activity. Further assays with mutated recombinant...

Báo cáo khoa học: "Molecular cloning of the cDNA of canine homeodomaininteracting protein kinase 2" ppsx

... stage. The study about the nucleotide sequence of canine HIPK2was performed for the development of cancer therapybecause the attack rate of cancer has been increaseddepending on longevity of pets ... Activation of HIPK2 leads to the selectivephosphorylation of p53, resulting in growth arrest and the enhancement of apoptosis. In this study, the canine HIPK2 cDNA fragments were obtained, and theiroverlapping ... and the enhancement of apoptosis[3]. Overexpression of HIPK2 leads to an increase of p53 protein expression or stability [19]. The research of p53 is being conducted to find the mechanisms of...

Báo cáo khoa học: "Molecular dissection of the quantitative inheritance of wood property traits in loblolly pine" pps

... been made toward the molecular dissection of the quantitative inheritance of wood property traits in loblolly pine (Pinus taeda L.) and several other forest tree species. QTL mapping experiments ... Diagram of the three-generation P. taeda pedigrees used in QTL mapping experiments. D.B. Neale et al .Wood property QTLsOriginal articleMolecular dissection of the quantitative inheritance of wood ... completely unknown. The focus of our research is to identify the genes control-ling wood property traits in loblolly pine (Pinus taeda L.), the most important timber species in the US. Our initial approachtoward...

Báo cáo khoa học: "Molecular characterization of the Great Lakes viral hemorrhagic septicemia virus (VHSV) isolate from USA" pot

... of the Novirhabdovirus genus. The termini of the viral genome have conserved sequences at the 3'-end (CAUAG/UU) and 5'-end (G/AAUAUG) asother members of the Novirhabdovirus genus. The ... and codingregions of several other strains of VHSV have been deter-mined later [10]. In this study, we characterized the entiregenome of the Great Lakes VHSV isolate MI03GL from muskellunge, ... about the viral hemorrhagic septicemia virus (VHSV) isolates used in this study for comparison and phylogenetic analysis (Continued) the DNA sequenced (Fig. 1). The complete genomesequence of...

Báo cáo khoa học: "Molecular characterization of the virulent infectious hematopoietic necrosis virus (IHNV) strain 220-90" doc

... in other IHNV strains. The first 15 of the 16 nucleotides at the 3’- and 5’-termini of the genome are complementary, and the first 4 nucleotides at 3’-ends of the IHNV areidentical to other ... Vakharia1*AbstractBackground: Infectious hematopoietic necrosis virus (IHNV) is the type species of the genus Novirhabdovirus,within the family Rhabdoviridae, infecting several species of wild and hatchery ... 7:10http://www.virologyj.com/content/7/1/10Page 9 of 11 RESEARC H Open AccessMolecular characterization of the virulent infectious hematopoietic necrosis virus (IHNV) strain 220-90Arun Ammayappan1,2,...

Báo cáo khoa học: "Molecular characterisation of virulence graded field isolates of myxoma virus" pot

... 7:49http://www.virologyj.com/content/7/1/49Page 3 of 12 RESEARC H Open AccessMolecular characterisation of virulence graded field isolates of myxoma virusKevin P Dalton*, Ines Nicieza, Aroa ... al.: Molecular characterisation of virulence graded field isolates of myxoma virus. Virology Journal 2010 7:49.Submit your next manuscript to BioMed Centraland take full advantage of: ã Convenient ... onlarge numbers of virus isolates are essential to differenti-ate the types of circulating MV -isolates and to identifynew emergent strains which might have differentdegrees of virulence. Hampered...

Báo cáo khoa học: "Molecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniae using cDNA microarrays" doc

... AccessResearchMolecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniae using cDNA microarraysJakob Hedegaard1, Kerstin Skovgaard2, Shila Mortensen2, ... Determination of their specific roles during infection may lead to a better understanding of innateimmunity in pigs. Competing interests The author(s) declare that they have no competing inter-ests.Authors' ... serofibrinous pleuritis [1]. Infection of the porcine lung with A. pleuropneumoniae has previouslybeen reported to result in a local production of proinflam-matory proteins or mRNA encoding the...

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