Báo cáo y học: " Antigen-sensitized CD4+CD62Llow memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting" pptx
Báo cáo y học: " Antigen-sensitized CD4+CD62Llow memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting" pptx
... produces Th2-type cytokines and directly induces transfer-mediated AHR. (A and B)CD4+CD62Llow memory/effector subset proliferates and produces Th2-type cytokines with antigen stimula-tion. ... proliferatedthere, then produced Th2-type cytokine, which resulted in the direct induction of AHR. They also indicated that anti-gen-pulsed memory/effector T cell phenotype might play an important role ... AHR.Discussion In the current study, we demonstrated that transfer of antigen- induced cellular immune response into naivemice reconstituted AHR in an antigen free setting. Wefound that CD4+CD62Llow Th2...
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Báo cáo y học: "Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ" potx
... suppressive activity of the T reg cells can be presented by plotting the percentage of inhibi-tion (100 × (Radioactivity in condition without T reg cells –Radioactivity in condition with T reg cells) /Radioactivity ... set of experiments we tested the importance of T reg cells in the pathogenesis of CIA by rendering wild-typemice deficient in T reg cells by treating the mice with deplet-ing anti-CD25 antibody. ... AACCTT; Foxp3-RV, TTC TCA CAA CCA GGC CAC TTG;Foxp3-TP, ATC CTA CCC ACT GCT GGC AAA TGGAGT C; TGF-β-FW, TGA CGT CAC TGG AGT TGT ACGG; TGF-β-RV, GGT TCA TGT CAT GGA TGG TGC; TGF-β-TP, TTC AGC...
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Báo cáo Y học: Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme pptx
... MCM2(169 21 2) domain interfere withthe binding of pol II and general transcription factors in vitro. (A) Theindicated amino acid substitutions were introduced into the GST-MCM2(169 21 2) peptide by ... It is thereforeunlikely that the deletion mutants were recruited to GST–TFIIS via interactions with complexes that already containendogenous MCM2.Fig. 6. Point mutations in the MCM2(169 21 2) ... ability of the MCM2(169 21 2) peptide to bindpol II and general transcription factors in vitro.Next we tested if the same mutations would interfere withthe binding of MCM2 to pol II holoenzyme in...
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Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx
... suggesting an important role in early stages ofinfection [3–6]. Vpr is involved in the transport of thepreintegration complex into the host cell nucleus, which is an important feature for infection ... Cryst. 26 , 28 3 29 1. 28 . Hutchinson, E.G. & Thornton, J.M. (1996) PROMOTIF – aprogram to identify and analyze structural motifs in proteins.Protein Sci. 5, 21 2 22 0. 29 . Rost, B. & Sander, ... therefore an interestingtarget for the development of antiviral agents. This96-amino-acid protein is an important factor for thepathogenesis of HIV [1 ,2] . Vpr is an integral part of viralparticles...
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Báo cáo Y học: Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates pptx
... due to the fact that it occurswithin the instrument’s dead time [21 ]. None of the E139FNR mutants show any detectable absorbance change in this reaction, which suggests again that the reactions ... different FNRmutants at E139 were determined for two reactionscatalysed in vitro by FNR by fitting the experimental datato the Michaelis–Menten equation.Diaphorase activity. The analysis of the kinetic ... showed interesting conformational chan-ges in the side-chain of another glutamic acid residue, E139,that in the mutant points towards the FAD cofactor in theactive centre cavity and is stabilized...
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Báo cáo y học: "Controlling Osteogenesis and Adipogenesis of Mesenchymal Stromal Cells by Regulating A Circadian Clock Protein with Laser Irradiation" pptx
... regulated by osteoblasts that differentiate from mesenchymal stro-mal cells (MSCs). MSCs are multipotent cells that can replicate as undifferentiated cells and that have the potential to differentiate ... Class I cyclobutane pyrimidine dim-mers (CPD) photolyase, although it does not exhibit photolyase activity. CRY also binds flavin adenine dinucleotide (FAD), 2, 3 consistent with CRY mediating ... rhythms are thought to confer a selective advantage to organisms by enabling them to pursue levels of activity that are optimal for growth and de-velopment and minimize susceptibility to...
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Báo cáo y học: "Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis" pps
... demonstrated that IFN-γFigure 6Cytokine concentrations in joint extracts at different time points after the induction of antigen- induced arthritisCytokine concentrations in joint extracts at different ... 4b).Safranin O stainingSafranin O staining reflects the proteoglycan content ofcartilage. Proteoglycan loss is an early marker of cartilagedestruction. The staining intensity of proteoglycans ... activity assay in joint extracts at different points of time in antigen- induced arthritis (AIA)Matrix metalloproteinase (MMP) fluorescence activity assay in joint extracts at different points...
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Báo cáo y học: "Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts" doc
... quality and magni-tude as those induced by polarized T cells. For instance, IL-8was not induced by any of the Th1 and Th2 cytokines, but wasstrongly induced by Th2 and to a lesser extent by Th1 cells ... levels induced by Th1 but not by Th2 cells (Figure6a,b). Of further interest, MCP-1 mRNA induced by Th1 cells was not significantly affected by any of the inhibitors used, butthe MCP-1 levels induced ... – an effect due to cytokines (IL-1 and TNF-α) shared by the two T cell subsets. This indicates that the biological activities of T cells do not simply mirror the cytokines that they preferentiallyproduce...
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Báo cáo y học: "Predicting outcome of rethoracotomy for suspected pericardial tamponade following cardio-thoracic surgery in the intensive care unit" ppt
... parameters including, forworst values within 24 h prior to rethoracotomy, worstvalue within and at 24 h after rethoracotomy, and forthose directly prior to and after rethoracotomy of, heartrate ... manuscript.Competing interestsThe authors declare that they have no competing interests.Received: 22 October 20 10 Accepted: 30 May 20 11Published: 30 May 20 11References1. Weitzman LB, Tinker ... the treat-ment of hypotension into account, and ranges from 0 to4 with 0 indicating normo-tension without treatment.We thus separated patients with and without a decreaseof CV SOFA score >...
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Báo cáo y học: "Unusual association of ST-T abnormalities, myocarditis and cardiomyopathy with H1N1 influenza in pregnancy: two case reports and review of the literature" pps
... rkforce takes on added importance in the setting of the H1N1 20 09 swine-origin influenzapandemic [22 ]. Inacti vated influenza vacci ne can besafely and effectively administered during any trimesterof ... amongst caregivers totarget this ‘at risk’ group aggressively with vaccination and prompt treatment.IntroductionMany previous studies have explored the link betweeninfluenza and myocarditis. Influenza ... (Figures 2 and 3) and she was started onintravenous antibiotics and zanamivir. Osteltamivir wasadded at a later date. As in our first patient, she contin-ued to deteriorate and developed severe type...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDETrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ