Báo cáo y học: "Effects of PM10 in human peripheral blood monocytes and J774 macrophages" doc
Báo cáo y học: "Effects of PM10 in human peripheral blood monocytes and J774 macrophages" doc
... particles may exert their pro-inflammatory effects by modulating intracellular calcium signalling in macrophages leading toexpression of pro-inflammatory cytokines. Impaired motility and phagocytic ... nacystelyn or the calmodulin inhibitor W-7. In human monocytes, PM10stimulated an increase in intracellular calcium which was reduced by verapamil, BAPTA-AM and nacystelyn. TNF-α release was increased ... result in a diminished cel-lular killing and clearance of particles and pathogens fromthe lung.The pro-inflammatory cytokine interleukin 1 (IL-1) is notnormally produced by the cells of healthy...
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Báo cáo y học: " Effects of different fibrinogen concentrations on blood loss and coagulation parameters in a pig model of coagulopathy with blunt liver injury" docx
... liver and the kidneys, were removed after death and directly fixed in 10% buffered formalin. Injured parts of the liver were cut into 3 mm thick slices. Only areas of maximum depth of injury and ... haematoxylin ascounterstain was used. A blinded pathologist subse-quently assessed the degree of injury in the liver and of fibrin deposition in vessels and microthrombi formation in all organs.Statistical ... blunt liver injury.Methods: Coagulopathy was induced in 18 anaesthetized pigs (32 ± 1.6 kg body weight) by replacing 80% of blood volume with hydroxyethylstarch 130/0.4 and Ringer's lactated...
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Báo cáo y học: " Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults" ppt
... potent inducer of CYPenzyme activity. Polymorphisms of CYP2B6 and CYP3A4 are associated with altered activity of hepatic enzyme in the liver and pharmacokinetics resulting in treatment efficacy. ... (62/65) of homo-zygous TT and 4.6% (3/65) of heterozygous TC, and 98.3% (58/59) of homozygous TT and 1.69% (1/59) of heterozygous TC in efavirenz and nevirapine groups,respectively.CYP2B6-G516T and ... by using QIAampDNA blood Mini kit (QIAGEN, Hilden, Germany) and stored at -20°C for SNP genotyping. Genotyping of alle-lic variants in CYP2B6 and CYP3A4 were carried out byreal-time PCR using...
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Báo cáo y học: "Effects of lifestyle physical activity on perceived symptoms and physical function in adults with fibromyalgia: results of a randomized trial" pdf
... activity, of moderate-intensity physical activity five to seven daysa week by integrating short bouts of activity into theday, such as increasing the amount of walking, perform-ing more yard ... accumulatedmoderate-intensity LPA five to seven days a week, and asked to increase the daily duration of LPA by five min-utes each we ek. The five-minute increase in the dailyduration of LPA was based on findings ... education and support meetings NO YESPhysical activity intervention delivered in six, one-hour meetings YES NOWear pedometer and keep a physical activity log YES NOPrescribed physical activity YES...
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Báo cáo y học: "Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice" pps
... tissues, including lung tissue [1]. Follow-ing bleomycin-induced injury in mice, mesenchymalstem cells colonized the lung and differentiate into type 1or type II pneumocytes [2,3]. In addition, human ... previously described [16]. After fixation and paraffin embedding, 5 µm-thick lung sections werecut and stained with hematoxylin-phloxine-saffron. In each mouse, 30 intraacinar vessels accompanying ... E, F and G) showed staining in the bronchi, alveolar wall, and distal vessels 5 and 15 daysafter MCTp injection.No eGFP immunostaining was detected in lung sectionsfrom chronically hypoxic...
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Báo cáo y học: "Effects of hydrogen sulfide on hemodynamics, inflammatory response and oxidative stress during resuscitated hemorrhagic shock in rats" potx
... effect of hydrogen sulfide in a murine model of acute lunginjury induced by combined burn and smoke inhalation. Clin Sci (Lond)2008, 115:91-97.31. Maines MD, Mayer RD, Ewing JF, McCoubrey WK ... Hydrogensulfide inhibits activity of three isoforms of recombinant nitric oxidesynthase. Toxicology 2007, 241:92-97.15. Ali MY, Ping CY, Mok YY, Ling L, Whiteman M, Bhatia M, Moore PK:Regulation of vascular ... equilibrate in deferoxamine-chelated Krebs-Hepes solution containing1 hydroxy-3methoxycarbonyl 2,2,5,5-tetramethylpyrroli-din (CMH, Noxygen, German y) (500 μM), deferoxamine(25 μM) and DETC (5...
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Báo cáo y học: "Effects of Flurbiprofen on CRP, TNF-α, IL-6, and Postoperative Pain of Thoracotomy"
... flurbiprofen. VAS scoring is a simple and often used method for evaluating variations in pain intensity. Subjects are instructed to indicate the intensity of the pain by marking a 100-mm line anchored ... Proinflammatory cy-tokines induce not only a local inflammation at the site of injury, but also systemic responses such as tachycardia, tachypnea, leukocytosis, and pyrexia (1). Increased levels of ... pain, Inflammatory response, Flurbiprofen Introduction Surgical trauma induces an inflammatory state characterized by the release of both proinflammatory and antiinflammatory proteins. Proinflammatory...
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Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
... between Cyt f and plastocyanin and/ or plasto-cyanin and photosystem I, and subsequently the nature of the interactions in the two lineages (hydrophobic in cyanobacteria, electrostatic in chloroplasts) ... thermodynamic analysis by laser-flash absorptionspectroscopy of photosystem I reduction by plastocyanin and cytochrome c6 in Anabaena PCC 7119, Synechocystis PCC 6803, and spinach. Biochemistry 35, ... protein plastocyanin can bereplaced by cytochrome c6, a redox protein of similar sizebut entirely different folding, in a number of eukaryoticalgae and cyanobacteria including P. laminosum...
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Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot
... these proteins can beactivated independently, suggesting that each link is func-tional [5–7]. In addition, in megakaryocytic cell lines and in primary megakaryocytes, the precursor of platelets, ... oncogene, which was in itsactivated state by constitutive binding of GTP. A number of proteins, including RAF, GAPp120, MEKK1, and phos-phatidylinositol-3 kinase (PtdIns3K) are able to interactwith ... Precipitatedproteins were resolved by 12.5% SDS/PAGE and analysed by Westernblotting using an anti-RAS Ig (top). Proteins of whole cell lysate wereresolved by 12.5% SDS/PA GE and a nalysed by Western blottingusing...
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Báo cáo y học: "Quality of life in mentally ill, physically ill and healthy individuals: The validation of the Greek version of the World Health Organization Quality of Life (WHOQOL-100) questionnaire" ppt
... consumption-related psychopathology and multi-ple acquired deficits in physical and psychological health, in social life, family, work and financial well-being [34-37].Regarding physically ill individuals, ... probablybe obtained in the facets of pain/discomfort (in the physicalhealth domain) and in experiencing positive feelings (in thepsychological health domain). Recent studies indicate thatboth of these ... [31].Aim of the study and research hypothesesThe aim of the present study was to examine the validity and reliability of the WHOQOL-100 Greek version and assess its suitability for identifying differences...
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