... Abraham
Unfortunately, in 2051 we will still have to deal with
endotoxin being released by Escherichia coli, but by then we
will be able to determine who will do poorly and who will do
well. By appreciating ... proteomics. By
2051 we will be able to identify which proteins are being
expressed, to what levels, how high or how low the protein
levels are in various cell typ...
... skills will be combined.
Surgery will become less invasive as imaging techniques
become more revealing.
Indeed, the next frontier in imaging will be to reveal not only
anatomy but also physiology ... it. In the future
we will have a better understanding of ‘host–microbial
Commentary
The International Sepsis Forum’s controversies in sepsis: how
will sepsis be...
... norepinephrine is
counterbalanced by an increased venous capacitance
Commentary
The International Sepsis Forum’s controversies in sepsis: my
initial vasopressor agent in septic shock is norepinephrine ... to be elevated
and patients receiving norepinephrine showed a statistically
and clinically significant decrease in levels. In another study
[14] treatment with a combinat...
... could be given to norepinephrine, but
these are exceptional cases.
Commentary
The International Sepsis Forum’s controversies in sepsis: my
initial vasopressor agent in septic shock is dopamine ... The International Sepsis Forum’s
controversies in sepsis: my initial vasopressor agent in septic
shock is norepinephrine rather than dopamine. Crit Care
2003, 7:3-5.
3....
... patient. Hayes and
Commentary
The International Sepsis Forum’s frontiers in sepsis: high cardiac
output should be maintained in severe sepsis
Jean-Louis Vincent
Head, Department of Intensive Care, ... 4 Vincent
Introduction
Sepsis is associated with systemic, mediator-induced
alterations in oxygen utilization, including increased oxygen
demand, altered oxygen extraction, a...
... by a
Commentary
The International Sepsis Forum’s frontiers in sepsis: high cardiac
output should not be maintained in severe sepsis
Vinay K Sharma
1
and R Phillip Dellinger
2
1
Attending Physician, ... VO
2
in septic patients [30].
In a more recent study [31], increasing doses of
phenylephrine in septic patients were shown to result in a
linear increase in MAP withou...
... Recombinant Human Activated Protein C
Worldwide Evaluation in Severe Sepsis; SAPS II: Simplified Acute Physiology Score II; SIRS: Systemic Inflammatory Response Syndrome; SSC:
Surviving Sepsis ... PROGRESS was an international
registry. Previous analyses of DrotAA -treated patients have
been registries for individual institutions or countries [7-15]. In
all cases, including PROGRE...
... the Insti-
tute for Evaluative Research in Orthopaedic Surgery at
the University of Bern, Switzerland, allows online and
offline data entry. All information is sent in an encrypted
fashion and in ... setting; this because of the modularity
how data can be recorded. The consistent use of the sys-
tem assures a stringent internal quality assurance, and
more interesting, an external qu...
... eagerly awaited [62].
Marcos Intraglietta (La Jolla, CA, USA) presented an
emerging alternative hypothesis to the dogma of maintaining
oxygen delivery by maintaining oxygen carrying capacity (i.e.
RBC ... varying tidal volume as would happen
physiologically) is an interesting new concept. It has been
shown to improve recruitment and to reduce interleukin-6
levels, and therefore may reduce lun...
... polysomes [7].
Homing activity of the I-DirI protein has been demonstra-
ted by Dir.S956-1 intron mobility studies involving genetic
crosses between intron-containing and intron-lacking
Didymium isolates ... splicing. They constitute one class out of fewer
than 10 classes of naturally occurring ribozymes [1].
Group I introns vary considerably in complexity. Most
introns contain only the seq...