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Báo cáo y học: "Pro/con clinical debate: Are steroids useful in the management of patients with septic shock" ppt

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Báo cáo y học: "Pro/con clinical debate: Are steroids useful in the management of patients with septic shock" ppt

... new orongoing infection. You wonder whether steroids might helpfacilitate his recovery.CommentaryPro/con clinical debate: Are steroids useful in the management of patients with septic shock?Frank ... Walley The debate surrounding the use of corticosteroids in septic patients has continued for over 30 years. Two meta-analyses in the mid-1990s seemed to put an end to the controversy. The conclusions ... repair of sepsis-induced dysregulation of vasomotor tone using low-dose corticosteroids is reasonableand appropriate.Con: steroids are not useful in the management of septic shockKatherine G...
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Báo cáo y học: "Low-concentration, continuous brachial plexus block in the management of Purple Glove Syndrome: a case report" pps

... veinresulting in disruption of the endothelial-intercellularjunctions and seepage of the drug into the interstitialspace [1]. Extravasation of the highly albumin-bound (70-90%) phenytoin increases the ... the advantage of blocking the sympathetic innervation of the upper limb,thus improving the perfusion and relieving the ischaemicpain associated with vasospasm [11].Because of tissue injury ... immediate discon-tinuation of the infusion and removal of the intravenouscatheter [1]. The diagnosis of PGS is based on the characteristic clinical findings and a high index of suspicion when...
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Báo cáo y học: "Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis" pdf

... have identified an increase in proteolytic activity within the glomerulus coinciding with the development of proteinuria in the (NXB×NZW)F1mouse model of systemic lupus erythematosus.Here we ... with evidence of central nervous systeminvolvement. There are reports indicating a central role forMMPs in increasing permeability of the blood-brain barrier in inflammatory settings [52], which ... Candidatemediators of such changes include enzymes and signallingsubstances involved in maintaining the delicate balancebetween synthesis and breakdown of the proteins andproteoglycans that make up the ECM.Although...
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Báo cáo y học: " HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic interventio" ppsx

... quantities of Vpr. 2). Vpr promotes the binding of the PIC (including MA, integrase (IN) and proviral DNA) to importins andnucleoporins, thereby facilitating nuclear entry of HIV-1 provirus into the ... found in brains of patients sufferingfrom HIV-D [155]. The presence of TNF-a protein andmRNA in patients with HIV-D has been reported to sig-nificantly correlate with the severity of symptoms in these ... coated with renal tubular epithe-lium [177]. In vivo, FGF-2 likely increases the invasion of inflammatory cells into renal tissue, leading to renalinjury. Interestingly, Vpr has been implicated in...
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Báo cáo y học: "Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomised controlled trial" pdf

... haemody-namic instability (five patients) , one refusal to continue in the study and nine complications were related to the ventilator and the automatic mode of weaning. In six of the patients, the ... during the weaning process. In some, instead of the pressure supportdecreasing gradually, it increased for a while and thendecreased until the point of extubation. In the manual mode of weaning ... as the patients re-assume their capability to breathe on their own, the weaning process starts. The success of the weaning dependsmore on the patients& apos; ventilatory capability than on the...
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Báo cáo y học: "Spinal manipulative therapy versus Graston Technique in the treatment of non-specific thoracic spine pain: Design of a randomised controlled trial" potx

... spine pain [11]Definition of non specific Thoracic spine painMidline back pain – for the purposes of this trial, the pain will be bound by the lateral margins of the thorax laterally and the ... the person requesting the randomisation hasconfirmed that they wish to proceed with entry into the trial. The participants will be analysed in the groups towhich they are randomised using intention ... old with a primarycomplaint of thoracic pain (Figure 1: Mannequin defining the area of thoracic pain) and with no contraindicationsto manual therapy or Graston Technique.Upon making an appointment...
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Báo cáo y học: "Is smaller high enough? Another piece in the puzzle of stress, strain, size, and systems" pdf

... (VA/Q) areas,indicating sustained derecruitment of the lungs. Thisphenomenon has also been demonstrated in the clinical setting by Richard and colleagues [7] in ARDS patients whilereducing the ... the concept of setting PEEP according to a table becomes evident, and in the present study, what is very probably a ‘false’ PEEPreduction (obviously triggered by the increase in the PaO2/FiO2[arterial ... Ideally, however, one venous double-lumencannula would ensure the vascular access, and a small pumpthat is very easy to handle may be integrated into the systemas a single-use product, delivering...
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Báo cáo y học: "Assessing food appeal and desire to eat: the effects of portion size & energy density" pptx

... studyinvestigating ‘opinions about food’ in the Denver Metroand Northern Colorado areas. No further informationregarding the purpose of the study was given. Indivi-duals were excluded if they had a visual ... level of fullnessand interactions where included in the repeated mea-sures analyses of vari ance model when testing the effect of portion size on ratings. In the case of a significantinteraction, ... more of a generalized, stable feeling. Finlayson and colleaguesreported differences in liking and wanting ratings whenindividuals were in differing energy states [16,17].Therefore, we hypothesize...
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Báo cáo y học: "Pro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis" ppt

... noobvious signs of infection, you wonder whether antibiotics are useful in the patient’s management. ReviewPro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis ... attractive as it may allow the use of prophylaxis without the risk of inducing superinfec-tions through the use of long-term broad-spectrum antibi-otics.These data support our opinion that patients ... necrosis[4].Pooling of the data from these 183 patients by Bosscha andcolleagues in a meta-analysis resulted in a group of 95 patients treated with prophylactic antibiotics and88 patients without [5]. These...
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Báo cáo y học: " Pro/con clinical debate: The use of prone positioning in the management of patients with acute respiratory distress syndrome" potx

... positioning.CommentaryPro/con clinical debate: The use of prone positioning in the management of patients with acute respiratory distresssyndromeJohn J Marini* and Gordon Rubenfeld†*Professor of ... feelobliged to offer some therapy, any therapy, to a patient in imminent danger of dying [16].As is often the case in critical care, a therapy that looks greatfrom a basic science standpoint does ... reduction in the risk of death, and there is certainly a possibility that a larger studywould yield positive results. Neither of these are verypersuasive arguments for using a therapy. The real...
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