... emphasis away from
linkage analysis and microsatellite markers towards SNP
genotyping and different analytical strategies based on
association and haplotype analysis [31–34]. Association
analyses ... pharmaceutical industry [4].
Asthma is a genetically complex disease that is associated
with the familial syndrome of atopy and increased levels of
total serum IgE [5,6]. Asthma and atopy...
... Medical Case Reports has
published the case of a 22-year-old lactating woman
who presented with four months of amenorrhea asso-
ciated with signs of virilization. The patient was diag-
nosed as having ... For example, ‘chemotherapy and
radiotherapy’ are indicated in the branch of the ‘fishbone’
that shows the cause of ovarian failure, a potential cause
for secon dary...
... of the analysis was
63 years (17–81 years), and 76% were female. A cohort of
171 healthy individuals matched on the basis of age, sex and
origin were used as a healthy control group. All protocols ... the classification of the disease,
were enrolled in the study. The 101 patients represented an
ethnically homogeneous cohort of Caucasian RA patients. The
median (r...
... plexity of the
infl ammatory process: the shedding of membrane
IL-18Rα as a marker of enhanced proteolytic activity; the
activation and release of IL-18 by the infl ammasome as a
marker of innate ... Matsunaga K, Sakazaki Y, Sawada M, Oda H, Takenaka S-I,
Imaoka H, Kinoshita T, Honda S, Ida S, Fukuda T -A, Aizawa H: Soluble
interleukin-18 receptor complex is a...
... antioxidant
capacity [17]. Unfortunately, Abboud and colleagues did not
report any of these measurements, and thus the impact of
oxidative or nitrosative stress on the catecholamine clearance
remains ... In
addition, other authors have emphasized that the sepsis-
related enhanced formation of nitric oxide and the superoxide
radical O
2
-
accelerates catecholamine deactivation du...
... cycle of che-
motherapy were included in the toxicity analysis. Hema-
tological toxicity grade ≥ 2 was observed in 22 patients,
and grade 3/4 wa s seen in 12 patients. Hepatotoxicity
grade ≥ 2 was ... histology, and o ther baseline
characteristics were evaluated by logistic regression. Sur-
vival was calculated by Kaplan-Meier method, and the
log-rank test was used to determine the...
... LMP1-CD40 induces increased secretion of inflammatory cytokines and b-chemokines.Human
inflammatory cytokine quantitation was performed by cytometric bead array (CBA). Cytokine concentrations from three ... with
LMP1 and LMP1-CD40 adjuvanted virus. Human inflammatory cytokine
quantitation was performed from the culture supernatants by cytometric
bead array (CBA). P values are shown for an...
...
increase in absence days/yr. A 10-day increase in ab-
sence days per annum (scale score ranging from 0-220
days/yr) yielded an increase in disability pension risk
of approximately 35% (Cochran-Armitage ... Study (DWECS) and the
national register on social transfer payments
(DREAM). DREAM is a register based on data from
the Danish Ministry of Employment, the Ministry of
S...
... that the probability of
the parse of a equals
1/3, and the
probability of the
parse of ab equals 4/9. The parse of a can exhaustively
be generated by applying rule
(2),
while the parse of ... language, .almost every input
string of reasonable length gets an unmanageably large
number of different analyses. Since most of these
analyses are not perceive...