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Báo cáo y học: " Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis" ppsx

Báo cáo y học:

Báo cáo y học: " Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis" ppsx

... inflammation is at the heart of the pathobiology of COPD and that the inflammatory process involves both the lung (airways and parenchyma) and the systemic circulation [32-34]. The intensity of the ... perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysisWen Qi Gan1,2, SF Paul Man1,2, Dirkje S Postma3, Patricia Camp1 and ... decline.Methods: A systematic review and a meta-analysis was performed of population-based cohortstudies that had a follow-up period of at least 3 years, measured FEV1 on at least two different...
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Báo cáo y học: "Noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease: a standard of care" ppt

... treat acute respiratory failure caused by chronic obstructive pulmonary disease (COPD)exacerbations as compared with ‘usual care’. Their analysisshowed substantial and statistically significant ... early’ to treat respiratory failure due to COPDexacerbations. In an accompanying editorial, Babu and Chauhan [2] advocated the ‘timely use of non-invasiveventilation in more severe exacerbations’. ... protect their airway or handleairway secretions or accommodate a mask, are routinelyexcluded. Admittedly, these selection criteria are largelysubjective and, like the decision to intubate, they...
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Báo cáo y học: "Two-year home-based nocturnal noninvasive ventilation added to rehabilitation in chronic obstructive pulmonary disease patients: A randomized controlled trial" pot

... with all data of all patients available at the start of the home-based period included for ana-lyses and all avail able data used for analyses untilpatients dropped out. A p < 0.05 was considered ... frequency, hospitalization rate for a COPD exacerba-tion or the numb er of hospitalization d ays. However inour cohort exacerbations did not occur frequently and the majority of the exacerbations ... Activity and Restriction Scale (GARS) [ 23])), pulmonary function(FEV1, vital capacity, and lung volumes), and exacerba-tion frequency. An exacerbation was defined as an epi-sode of increased pulmonary...
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Báo cáo y học: "Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities" ppt

... other databases, such as RefSeq and Vega, and non-codingfunctional elements such as untranslated and regulatory regions. The number of variants per base pair (variantdensity) and our ability ... which are approxi mately 70% GC, had appro xi-mately half of the sequence depth of coverage as the CCDS regions, approximately 50% GC. When comparedto WGS (non-capture) data the same general biaseswere ... identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet 2010, 42:840-850.9. Bilguvar K, Ozturk AK, Louvi A, Kwan KY, Choi M, Tatli B, Yalnizoglu D,Tuysuz B, Caglayan AO,...
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Báo cáo y học: " Concomitant homozygosity for the prothrombin gene variant with mild deficiency of antithrombin III in a patient with multiple hepatic infarctions: a case report" pdf

... hepatic infarction is rare because of the richly anasta-mosing collateral arterial supply, and the dual blood sup-ply from the portal vein and hepatic artery. In this case,there was portal hypertension ... hypertension as evidenced by splenom-egaly, thrombocytopenia, and peri-gastric venous varices. The portal vein may have thrombosed and recanalised,similar to the patient's leg DVT and the hepatic ... later, he com-plained of increased lethargy with reduced appetite. A unilateral leg oedema was noticed. A gastroscopy wasnormal and a computed tomography (CT) scan con-firmed splenomegaly...
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Báo cáo y học: "A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis" ppt

... analy-sis, and helped to draft the manuscript. TRV-R participated in the acquisition and interpretation of data. LR participated in the acquisition and interpretation of data. JAM-F participated in the ... participated in the anal-ysis of the data. JM and MAG-G made substantial contributions to conception and design of the study, acquisition of data and coordination, helped to draft the manuscript and ... in the design of the study and indata analysis, and helped to draft the manuscript. CG-J performed the ultra-sonographic studies, participated in the design of the study and in data analy-sis,...
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Báo cáo y học: "Autoantibodies specific for apoptotic U1-70K are superior serological markers for mixed connective tissue disease" pdf

... and analyzed the immunoassays. DRcollected the patient sera. FH provided patient data. GPparticipated in the design of the study and in the analysis of the immunoassay results. WV conceived of ... show that autoantibodies against70Kapop are not significantly correlated with disease flares.MethodsPatient seraAll patients were seen at the Department of Rheumatology of the University Medical ... 2Longitudinal anti-70K analysis of patient T2Longitudinal anti-70K analysis of patient T2. Eighteen serum samples taken over a period of 7 years with approximately equal time intervals were analyzed...
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Báo cáo y học: " Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan" ppt

... ResearchInstitutes, Taiwan.Authors’ contributionsCJC and LIH had full access to all of the data in the study and takeresponsibility for the integrity of the data and the accuracy of the dataanalysis. ... Whitbread AK, Tetlow N, Cavanaugh JA,Blackburn AC, Masoumi A: Characterization of the monomethylarsonatereductase and dehydroascorbate reductase activities of Omega classglutathione transferase variants: ... fundingorganization played a role in the design and conducted of this study;collection, management, analysis, and interpretation of the data; orpreparation, review, and approval of the manuscript.Received:...
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Báo cáo y học: " All that glitters is not gold - founder effects complicate associations of flu mutations to disease severity" ppt

... phenoty-pic changes. The particular case of disease severity association of HA-Q310 H was proposed by Glinsky [10] based in parton the analysis of 7 Brazilian fatal cases where 3 of themhad the ... from the city of Sao Paulo) and narrow temporal window (all death case sampleswithin 1 month), it becomes clear that HA-Q310 H was actually a generally common mutation in the region at thattime ... 7:297http://www.virologyj.com/content/7/1/297Page 5 of 7Indeed, although HA-D239G is generally rare, it wasfound in 7% of all global death cases [9]. It has alsobeen shown to alter the biology of the virus [25] and mayberationallyassociatedwithseveritybyswitchinghost...
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Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps

... Hereditaryangioedema: a current state -of -the- art review, VII: Canadian Hungarian2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Ann Allergy Asthma ... syndromes, nausea, vomiting,diarrhea, and life-threatening airway swellings.Untreated airway angioe dema has an associated signifi-cant risk of dying from asphyxia. The first angioedemamay be a life-threatening ... with large phase IV clinical trials, meta analyses,data base registry validation of ap proaches including quality of life and cost benefit analyses, safety, and head-to-head clinical trials investigating...
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