... purposes)
Rapamycin reverses hypoxia-induced thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 6
Rapamycin reverses hypoxia-induced thickening of the right ventricular ... purposes)
Rapamycin attenuates hypoxia-triggered thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 4
Rapam...
... find-
ings in the lung in vivo, determination of pulmonary
function is an essential tool. Existing methods for measur-
ing respiratory function in mice in vivo include invasive
and noninvasive ... responsiveness (AR) in intact,
spontaneously breathing BALB/c mice.
Methods: Using noninvasive head-out body plethysmography and the decrease in tidal
midexpiratory flow (EF
50
),...
... number, and the date of
drug dispension. Since January 1 1989 all data from
North Jutland County have been stored in a
prescription database maintained by the Department
of Clinical Epidemiology, ... 30 days before conception and six months
post-delivery. In the first analysis, cases were defined
as boys with hypospadias recorded in the HDR
during the first six months post-de...
... sites of chymotrypsin. D-Chymotrypsinogen is a
chimera constructed to contain a trypsinogen propeptide
instead of the Cys1–Cys122-linked wild-type chymotryp-
sinogen peptide. D-Chymotrypsinogen also ... of
mammalian chymotrypsins and trypsins.
The enzyme that was used in this study, rat
chymotrypsin B, is highlighted by bold type.
The loops are boxed and labelled. Chymotryptic
and try...
... islets and liver of fetal, suckling
and adult rats
We studied the enzyme activities of two protein complexes
involved in the respiratory chain: succinate dehydrogenase
(complex II) and cytochrome ... in the c oncentrations of rat live r cyclic AMP and
of serum glucose, free fatty acids, insulin, pancreatic and
totalglucagoninthemanandintherat.J. Lat. Clin. Med. 82,
957±967.
5. M...
... on the brain imaging, involving the left insu-
lar and anterior temporal cortex, two brain regions fre-
quently involved in aphasic syndrome but also in FAS, a
cerebrovascular origin must be ... on the brain imaging, involving the left insular and
anterior temporal cortex, two brain regions frequently involved in aphasic syndrome but also in
FAS, a cerebrovascular origin must be c...
... subdimensions
(that is, hyperactivity and inattention). This finding may
reflect the inability to assess the multidimensional atten-
tion deficit hyperactivity disorder through only five items
different in nature ... cannot stay
still for long' and 'I am constantly fidgeting or squirming'.
These findings indicated that the aforementioned items
create a subdimension within...
... alter
the binding with selectins because the latter bind several
glycoproteins [53]. HYA and other GAGs could decrease
cytokine gene expression directly [54] or indirectly by
binding the CD44 ... Medicine, University of Messina, Messina, Italy
3
Department of Experimental and Clinical Medicine and Pharmacology, School of Medicine, University of Messina, Messina, Italy
Corresponding auth...
... metalloproteinase (MMP)
expression and activation in the medium were analysed by
gelatin zymography, proteoglycan release by the
dimethylmethylene blue assay, and cell viability by the
Cytotox 96
®
assay. ... c-fos and c-jun and by proinflammatory
cytokines that are known to be involved in arthritic dis-
eases [4,5], such as interleukin-1 and tumour necrosis
factor α (TNF-α). TN...
... Phar-
macokinetics and pharmacodynamics of IFN-beta 1a in
healthy volunteers. J Interferon Cytokine Res 2000, 20:857-
866.
28. Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y,
Yamamoto A, Pando ... per injection per mouse), limited hyperplasia of
the intimal lining layer and cell infiltration of the synovial sublining were
detected and a decrease in bone erosions was ob...