Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt

Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt

Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt

... of these cells. Density of neutrophils in synovial tissues of patients with OA and RA The presence of HNP1-3 prompted us to study the den- sity of elastase-positive neutrophils in synovial tissues ... defensins from synovial tissue/ cells and density of synovial neutrophils. (a) Levels of human neutrophil pep- tides 1-3 (HNP1-3) in superfusate o...
Ngày tải lên : 12/08/2014, 14:22
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Báo cáo y học: " α Tumor necrosis factor-α and muscle wasting: a cellular perspective" docx

Báo cáo y học: " α Tumor necrosis factor-α and muscle wasting: a cellular perspective" docx

... degradation. The marked protein is then degraded by the 26S-proteasome complex, by an ATP-dependent process. In catabolic states, the activity of the ubiquitin/ proteasome pathway is increased by upregulation ... that involves phospho- rylation and proteasomal degradation of the NF-κB- inhibitory protein, Iκ-Bα [13]. NF-κB activity in the cell nucleus peaks within...
Ngày tải lên : 12/08/2014, 18:20
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Báo cáo y học: "Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte" pptx

Báo cáo y học: "Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte" pptx

... promotes further expression of cytokines and chemokines by synovial cells and chondro- cytes, thereby sustaining a renewal of local inflammatory mediators (reviewed in [9,10]). The presence of TNF-α ... morphology. The MAPK/ERK pathway is thereby at least partially involved in regulating the aggrecan and type II collagen genes and in remodeling of the cytoske...
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes" ppt

Báo cáo y học: "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes" ppt

... was involved in the design of the study, performed all the experiments and wrote the manuscript. PB was involved in performing cell cultures, flow cytometry and gel shift assays, and reviewed the ... design of the study and reviewed the article critically. AC was involved in the conception and design of this study, in the interpretation of data an...
Ngày tải lên : 09/08/2014, 10:20
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Báo cáo y học: "Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis" pptx

Báo cáo y học: "Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis" pptx

... expression levels of TIARP mRNA and proteins were detected in splenocytes on day 7 (the onset of arthritis). In joints, the expression of TIARP mRNA and protein was correlated with joint swelling (days ... These findings suggest that the systemic upregulation of TNFα and TIARP is involved in the early phase of the disease and that TIARP expression in arth...
Ngày tải lên : 09/08/2014, 14:22
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Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx

Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx

... manuscript critically for important intellectual content. BK was involved in the conception and design of the study, analysis and interpretation of the data, and did most of the drafting of the manuscript. ... van den: Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of...
Ngày tải lên : 09/08/2014, 14:22
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Báo cáo y học: "α Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification" pps

Báo cáo y học: "α Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification" pps

... http://arthritis-research.com/content/7/3/R439 123 decrease in the hypervascularity typical of SpA and a reduction of the synovial lining hyperplasia, indicating that infliximab also modulates the structural synovial charac- teristics of the disease. ... acceptable safety profile in the chronic treatment of rheumatoid arthritis. Not only did the therapy turn ou...
Ngày tải lên : 09/08/2014, 06:23
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Báo cáo y học: "Tumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells" ppt

Báo cáo y học: "Tumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells" ppt

... abolished the DNA-protein binding activity induced by HBO. Exogenous addition of TNF-a significantly increased the DNA-protein binding activity. To study whether the visfatin expression induced by HBO ... HBO-induced visfatinproteinexpressionin human CAECs. Thirdly, JNK kinase and AP-1 transcrip- tion factor are involved in the signaling pathways of visfa- tin inductio...
Ngày tải lên : 10/08/2014, 05:21
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Báo cáo y học: "Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-B-dependent pathwa" pptx

Báo cáo y học: "Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-B-dependent pathwa" pptx

... pyrimidine s for DNA and RNA synthesis and accu- mulation of AICAR. AICAR, by inhibiting enzymatic deamination of adenosine and adenosine monopho- sphate, is proposed to increase availability of ... signaling. Conclusions: These find ings provide another mechanism by which TNF-a sustains macrophage numbers in inflamed tissue and identify a further point of clinical com...
Ngày tải lên : 12/08/2014, 15:22
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Báo cáo y học: "Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease" doc

Báo cáo y học: "Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease" doc

... characterized by a chronic inflammatory process, in which the pro-inflammatory cytokine Tumor Necrosis Factor (TNF)-α is considered to play a role. In the present study the putative involvement of TNF-α ... would further enhance the strength of these kinds of stud - ies. The gene polymorphism of TNF-α +489G/A was de- scribed for the first time in 1996 and...
Ngày tải lên : 12/08/2014, 18:20
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