... Helsinki, Helsinki, Finland,
5
Department of Internal Medicine/
Respiratory Medicine and Allergology, Sahlgrenska Academy, University of Gothenburg, Sweden and
6
Division of Clinical Physiology ... Helsinki-bronchodilation responses, determinants, and
intrasession repeatability of FEV1, FEV6, FVC, and forced
expiratory time A report from the FinEsS-Helsinki II study....
... possibly a
consequence of the decrease in the incidence of mental disorders as a result of the
development of an integrated and community-based mental health system, which in
turn may have led to ... explanations to the findings in the 16-64 and 65+ age bands. In theory,
fewer hospital admissions may just reflect a decrease in the general prevalence...
... http://arthritis-research.com/content/7/2/R268
R270
ability of antithrombin to inhibit thrombin. This finding helps
to explain why RA occurs and develops in joint tissue,
because the inflamed RA synovium is uniquely rich in free
HA and other GAGs, ... of
antithrombin. However, such binding did not stimulate the
activity of antithrombin as did heparin and heparan; in...
... in a vari-
ety of systems. This pyridine derivative is the oldest syn-
thesised and reported specific inhibitor of Rho-kinase
family enzymes. Y2 7632 inhibits ROCK activity by com-
petitive binding ... immunohistochemistry reagents and labora-
tory space. Dr F Henle instructed EF in the use of the image analysis soft-
ware. Prof B Stark of the Department of Plastic...
... high intensity by IgG from SSc
patients were analysed by using Pathway Studio soft-
ware. Interestingly, most of these proteins were involved
in the transforming growth factor b (TGF-b)pathway
(Additional ... protein (far upstream element-binding protein 2);
LMNA: lamin A/C; PCBP2: poly(rC)-binding protein 2; PRDX2: peroxiredoxin 2; RB1: retinoblastoma-associated protein; RBBP4: retinob...
... Tax1 and Tax2 are
found in the nucleus and in the cytoplasm in different
proportions: Tax1 being more abundant in the nucleus,
while Tax2 is more prone to be found in the cytoplasm
[16,35]. In the ... was also fused
to the N-terminus of the GFP (NES1-EGFP). In the
absence of a Tax NES sequence, the GFP protein is nearly
equally distributed between...
... varying
responses to INO. Besides, a limitation may include the intra-
variability and intervariability of the animal lung injury model.
On the contrary, most parameters of the inflammatory media-
tors measured ... animals. The aim of the study
was to compare physiological and biochemical events to try to
elucidate the mechanisms of response and nonrespon...
... of DTD activity, either due to knockout of the
DTD gene or by dicoumarol enzyme inhibition, causes an
increase in quinone dependent toxicity [12,35]. The cells
inability to break the redox cycling ... most potent
inducer. DHNQ also induced the activities of glutathione
peroxidase and γ-glutamylcysteine synthetase, the rate-
limiting enzyme in the glutathione synthe...
... from the complications caused by the
initial insult.
Few patients underwent dialysis in the present study, similar to
the frequency of dialysis (11%) reported by Clermont and
coworkers [20] in ... diag-
nosis of which is usually based on clinical findings, is the most
common cause of ARF in the hospital and in the ICU [3]. ATN
may occur after ischaemic or nep...
... haemodynamics may be
considered a major weakness of the study. However, the
intention was to investigate the immediate effects of early
intubation in an emergency situation, and under these
conditions ... in the given
respiratory situation most of the patients did profit from
intubation in terms of S
CVo
2
, but - strikingly - in patients with
low S
CVo
2
before...