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Báo cáo y học: " Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation" docx

Báo cáo y học:

Báo cáo y học: " Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation" docx

... pro-inflammatoryagents. Inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and increased tachykinin levels are ... [11]. The tachykinins, substance P and neurokinin A, arepresent in sensory afferent nerves and inflammatory cells in the airways. They may be released by a variety of stimuli(e.g. cigarette ... neurogenic inflammation in the airways [21].Furthermore, cigarette smoke-induced airway neu-trophilia was attenuated by a dual tachykinin NK1/NK2 receptor antagonist in guinea pigs [22]. The purpose...
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Báo cáo y học: " Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host disease" ppt

... primary biliary chirrho-sis, and Sjogren's syndrome, which are characterized by lym-phocyte infiltration into organs such as the kidneys, liver andsalivary glands [6]. In contrast, the parent-into-F1 ... coordination of the study, and participated in the interpretation of the results. JF participated in the HGFgene preparation and transfection. HS participated in the design and interpretation of the ... may represent a novel strategy for the treat-ment of systemic lupus erythematosus, Sjogren's syndromeand primary biliary cirrhosis.Competing interests The authors declare that they have...
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Báo cáo y học: "Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician’s mind" pdf

... evaluation of RA activity, and acute-phase reactants. The SDAI and CDAI also include the physician’s assessment of RA activity, and do not requiretransformation or weighting of the individual ... or the use of a calculator. In addition, the CDAI is the only indexthat does not include a measure of acute-phase response. All of these individual variables that are pooled in the variousindices ... variousindices have face validity in the context of measuring RAactivity. In other words, each variable, if available, is likely tobe considered in the implicit clinical assessment of RAactivity by the...
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Báo cáo y học: "Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways" ppsx

... Watanabe M, Ohsugi T, Shoda M, Ishida T, Aizawa S, Maruyama-NagaiM, Utsunomiya A, Koga S, Yamada Y, Kamihira S, Okayama A, KikuchiH, Uozumi K, Yamaguchi K, Higashihara M, Umezawa K, Watanabe ... Ishida T, Yamaguchi K,Watanabe T, Umezawa K, Urano T: In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia. Carcinogenesis ... Dewan MZ, Terashima K, Taruishi M, Hasegawa H, Ito M, Tanaka Y, Mori N, Sata T, Koyanagi Y, Maeda M, Kubuki Y, Okayama A, Fujii M,Yamamoto N: Rapid tumor formation of human T-cell leuke-mia...
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Báo cáo y học: "Phase delaying the human circadian clock with a single light pulse and moderate delay of the sleep/dark episode: no influence of iris color" potx

... AfricanAmericans had larger phase advances than Caucasians.Because we found that African Americans had a shortertau than Caucasians, which would augment phaseadvances relative to the Caucasians ... samples were shipped on dry ice to Pharma-san Labs (Osceola, WI) and radioimmunoassayed formelatonin. The sensitivity of the assay was 0.7 pg/ml and the intra- and inter-assay coefficients of ... have also administered phasedelaying light pulses on a single day. Understanding howmuch a single pulse of light can delay the circadian clockis important because practical constraints in the...
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Báo cáo y học: "Long term follow up after surgery in congenitally corrected transposition of the great arteries with a right ventricle in the systemic circulation" pot

... range 7 days - 32.0years).Coronary anatomy In 13 out of the 32 patients information on coronaryanatomy was explicitly available. In one patient a cir-cumflex coronary artery arose from the right ... coronary arterial anatomy in CCTGA [30]. Although the information in our study was incomplete, a word o fcaution may be relevant with regard to an increasedincidence of abnormal anatomy of the ... transplanta-tion. The second patient also had a dextrocardia, withadditionally mitral and aorta regurgitation, resulting in cardiac failure, finally leadi ng to cardiac transplantation.The...
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Báo cáo y học: " Magnetic resonance imaging with pathological correlation in a case of mantle cell lymphoma of the parotid gland: a case report" ppsx

... CAS E REP O R T Open AccessMagnetic resonance imaging with pathologicalcorrelation in a case of mantle cell lymphoma of the parotid gland: a case reportMayia Pilavaki1*, Anastasia Athanasiadou2, ... dis-ease at the time of diagnosis [2]. According to Argatoffet al., the isolated extranodal location of the disease hasbeen referred in 25% of cases, whereas salivary glands arerarely affected ... well-circum-scribed, partly cystic and partly solid lesions on MRI andare often located in the tail of the parotid gland. Adenoidcystic carcinoma usually presents as an infiltrating masswithahighpropensityforperineuralinvasion.OnMRIadenoid...
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Báo cáo y học: " Successful long-term monotherapy with rituximab in a patient with chronic lymphocytic leukemia of the B-cell-lineage: a case report" pdf

... with virtualdisappearance of normal leucocyte precursors and meg-akaryocytes on a bone marrow aspirate, as well as by a lack of efficacy. Although pulmonary infections are still a dan-gerous ... rituximab wastapered, with two administrations of 375 mg/m2 in Janu-ary and in April 2006. Since WBCs started to rise again 7months after the last administration, rituximab mainte-nance therapy ... severe autoimmune reactionagainst all three lineages of hematopoiesis, includingearly precursors (i.e., amegakaryocytic thrombocytope-nia). In our opinion, further chemotherapy was particularlydangerous...
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Báo cáo y học: " Ultrastructural changes of the intracellular surfactant pool in a rat model of lung transplantation-related events" pdf

... donororganhasbeenshowntoplayanimportantrolewithrespect to the pathogenesis, resulting in an interstitialand alveolar edema, injury of the blood-air barrier withfragmentation of the alveolar epitheli al lining and ... decrease in the number of Lb per cell accompanied by an increase of theluminalsurfaceareaoftheAE2cells,whichisanindirect sign of a fusion of the limiting membrane with the luminal surface. The total ... 1. The alveolarspace is filled with alveolar edema (ed) and erythrocytes (ery). The blood-air barrier is damaged as indicated by the fragmentedalveolar epithelial lining (*) including areas...
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Báo cáo y học: "Universal access: the benefits and challenges in bringing integrated HIV care to isolated and conflict affected populations in the Republic of Congo" potx

... follow rather than having to rely on clinicalassessments alone. A Sysemex machine capable of per-forming automated CD4 counts was introduced into the Mindouli laboratory. In the same logic, an automated ... sophisticated laboratoryequipment.Catalyst for engagement The introduction of HIV care, initially by an internationalNGO, acted as a catalyst for the MoH and other actors toengage and commit ... rural and remote settings where they have the potential to save lives and play a key role in helping toachieve universal access to ART in Africa.Competing interests The authors declare that they...
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