Báo cáo y học: " Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA Study" doc

... al.: Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA Study. Arthritis Research & Therapy 2010 12:R42.Submit your next manuscript ... Investigators:Argentina: Sergio Toloza, Santiago Aguero, Sergio Orellana Barrera, SoledadRetamozo, Hospital San Juan Bautista, Catamarca; Paula Alba, Cruz Lascano,Alejandra Babini, Eduardo Albiero, Hospital ... Magdy,Hany Aly, Hatem Saeid, Ahmad Nagm, Al-Azhar University, Cairo; Nihal A Fathi, Assiut University Hospital, Assiut; Esam Abda, Zahra Ebraheam, AboSohage University Hospital, Sohage.Estonia: Raili...

Báo cáo y học: "External validation of a modified model of Acute Physiology and Chronic Health Evaluation (APACHE) II for orthotopic liver transplant patients" docx

... Care Department, King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia4Chairman, Hepatobiliary Sciences and Liver Transplantation Department, King Fahad National Guard Hospital, ... Hospital, Riyadh, Kingdom of Saudi Arabia5Chairman, Intensive Care Department, King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia6Director of Liver Transplantation, University of ... resistance,an increase in cardiac output, a decrease in pH, an increase in lactate, an increase in potassium, and a prolongation ofprothrombin time [16,17]. Although some of these abnormali-ties...

Báo cáo y học: "Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells" ppt

... 48 hlater by trypsinization and were washed in phosphate-buffered saline and fixed for 15 minutes in paraformalde-hyde (1% in PBS) for in situ incorporation analysis. Inter-phase preparations ... Zamboni1, Yoichi Iwanaga2 and Kuan-Teh Jeang2Address: 1Department of Biology, University of Padua, Padua, Italy and 2Laboratory of Molecular Microbiology, NIAID, NIH, Bethesda, Maryland, ... telomericrepeats may also be transiently added to de novo interstitialchromosomal breaks leading to their stabilization andpreventing further exacerbation of damage [22]. Accord-ingly, DNA-ends or DNA-breaks...

Báo cáo y học: "Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy" ppt

... Matsui T, Shimada K, Ozawa N, Hayakowa H, Hagiwara F,Nakyama H, Sugii S, Ozawa Y, Tohma S: Diagnostic utility ofanti-cyclic citrullinated peptide antibodies for very early rheu-matoid arthritis. ... interpretation of data and was the main contribu-tor to the preparation of the manuscript. SGM contributed to the acquisition and analysis of the data and to the preparationof the manuscript. AB ... a statistical evaluationof these data. Changes in anti-mutated citrullinated vimentin titres during infliximab therapyOf the 80 patients with anti-CCP antibodies, 23 started inflix-imab therapy...

Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx

... Nevertheless, these data highlight the role played by PTP-α as a key upstream regula-tor of integrin-mediated signalling, linking ECM signals tocell migration and Src-FAK signalling.Integrin-mediated ... illustrating the importanceof cytokine-mediated activation, as well as accumulatingevidence for stable alterations in the intracellular signallingof RA-SFs. Thus, a recent study linked cytokine-mediatedexpression ... production[13]. In addition, PTEN, a tyrosine phosphatase that inter-acts with FAK and negatively regulates integrin-mediatedcell spreading, is not expressed in RA-SFs of the mostsuperficial lining layer...

Báo cáo y học: " Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab the" pdf

... citation purposes)early RA in our study was too small for a statistical evaluationof these data. Changes in anti-mutated citrullinated vimentin titres during infliximab therapyOf the 80 patients ... Matsui T, Shimada K, Ozawa N, Hayakowa H, Hagiwara F,Nakyama H, Sugii S, Ozawa Y, Tohma S: Diagnostic utility ofanti-cyclic citrullinated peptide antibodies for very early rheu-matoid arthritis. ... Bombardieri M, Papa N, Cinquini M, Magrini L, Tin-cani A, Valesini G: Decrease of anti-cyclic citrullinated peptideantibodies and rheumatoid factor following anti-TNF-alphatherapy (infliximab)...

Báo cáo y học: "Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis" pot

... using gapdh (glyceraldehyde-3-phosphate dehy-drogenase) as an internal reference.Table 1Clinical data of five patients with rheumatoid arthritis at the time of joint surgery a Patient Disease ... upstream protein of the Akt signalingpathway in RA FLSs. However, in vivo, abundant intracellularanti-apoptotic apparatuses generated by external survival/growth signals appear to overcome the ... has a pro-apoptoticrole in RA FLSs.Introduction Rheumatoid arthritis (RA) is a chronic inflammatory disorderthat involves mainly joint synovium. One of the major charac-teristics of RA synovium...

Báo cáo y học: "Novel multiplex technology for diagnostic characterization of rheumatoid arthritis" pdf

... biomarker assay in stratify-ing RA into clinically relevant subtypes. The ability to clas-sify RA patients in an automated and reproducible mannerpaves the way for further studies aimed at attaining ... stratify RA patients in an automated andreproducible manner paves the way for the development of assays that can guide RA therapy.Introduction Rheumatoid arthritis ( RA) is a systemic inflammatorycondition ... from this analysis. Autoantibody reactivity was assessed on the IMPACT platform and cytokine levels were measured in a bead-based assay run on the Luminex platform. For assays run on the IMPACT...

Báo cáo y học: "Marked disability and high use of nonsteroidal antiinflammatory drugs associated with knee osteoarthritis in rural China: a cross-sectional population-based survey" ppt

... completed an interviewer-based questionnaire, evaluating knee painand associated disability, analgesia, and health services use, and obtained bilateral standardized weight-bearingknee ra diographs.Results: ... from all study participants accord-ing to the Declaration of Helsinki.ParticipantsTrained health professionals administered the surveyquestionnaires, as it was anticipated that many study par-ticipants ... participated in the concept and design of the study, and the acquisitionand interpretation of the data. MF participated in the concept and design of the study, data interpretation, and helped draft the...

Báo cáo y học: "Do we need a critical care ultrasound certification program? Implications from an Australian medical-legal perspective"

... accepting the fee, the doctor has a contractual duty to provide a AbstractMedical practitioners have a duty to maintain a certain standard of care in providing their services. With critical care ... it is inevitable that ultrasound will become an indispensable tool in the next few years. In fact, many ICUs nowadays have an ultrasound machine available in their units, or at least accessible ... perform a vaginal hysterectomy that was beyond the capacity of the registrar in question. As a result of poor surgical skills, the patient’s fallopian tube was entrapped in the suture line and later...

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