... microorganisms. More than 80antimicrobial peptides have been isolated from only 12species of the Phyllomedusinae subfamily, belonging to the genera Agalychnis, Hylomantis, Pachymedusa, and Phyllomedusa. ... and operated under the control of masslynx 3.5 software(Waters) [46].Solid-phase peptide synthesis and purificationSynthesis and purification of the peptides were performedby the platform ‘Inge´nierie ... for other agonists [20], the interaction of DRS-DA4, presumably with FPRL-1, led to the activation of the ERK1 ⁄ 2 MAPK pathway, but not to that of the p38 MAPK pathway. The chemotaxis datasuggested...