... adiponectinemia in human obesity are, in the end, a summation of all of these effects. Interestingly, in rodents, the amelioration of glucose intolerance and insulin resistance observed following ... able to find any pro-inflammatory effect of 2-AG (data not shown). According to that, we can conclude that the anti-inflammatory effect of SR141716A is not due to the blockade of 2-AG binding. ... due to inverse agonism or to antagonism of tonically active endocannabinoids, we analysed whether or not LPS induces the formation of 2 endocannabinoids, 2-arachidonoyl glycerol (2-AG) and...