... adipogenesis, andincreased insulin sensitivity when on the HF diet.Thus, we show, for the first time, that PGD2isinvolved in the activation of adipogenesis and regula-tion of insulin sensitivity ... were increased in TG mice by the HF diet.mRNA expression of adipogenic genes in WAT of TG miceWe measured the amounts of PGD2 in WAT after6 weeks of the HF diet. WAT of TG (S55) mice con-tained ... levels of adipogenic genes, includingseveral PPARc-target genes, the transcription of which is enhanced in adipogenesis [31,32]. The expres-sion levels of PPARc, fatty acid-binding protein 4,Human...