Báo cáo y học: " Genetic predisposition to chikungunya – a blood group study in chikungunya affected families" pot

... susceptibility/resistance to chikungunya in the chikungunya affected families.During outbreak of chikungunya in Andhra Pradesh,India, a total of 100 chikungunya affected families fromnearby villages of ... Community Medicine, Government Medical College, Anantapur – 518001. IndiaEmail: Sudarsanareddy Lokireddy - l_suda2003@yahoo.co .in; Vemula Sarojamma - vemula_saroja@yahoo.co .in; Vadde Ramakrishna* ... consent and identified Blood groups by using commercial blood group kit containingAnti -A, Anti-B and Anti-D monoclonal antibody reagents.Statistical analysis was performed by using GraphPadInStat...

Báo cáo khóa học: Genetic approaches to the cellular functions of polyamines in mammals potx

... animal modelshave not fully translated to clinical practice apparently due to the sophisticated compensatory mechanisms aimed atmaintaining polyamine homeostasis [25,26]. In fact, poly-amines ... depleted pancreaticpolyamine pools came from experiments showing that the in ammatory process could be totally prevented, as judgedby histopathology and plasma a- amylase activity, by a prioradministration ... exists that assigns speciﬁcroles to the polyamines in general and to individualpolyamines in particular. The polyamines, especially sper-midine and spermine, interact with DNA with reasonablespeciﬁcity....

Báo cáo y học: "Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab" ppsx

... fordaily practice, since discontinuation of therapy at certainintervals, such as after 1 or 2 years of therapy, may become a standard approach. Payers and patients may want to make sure that further ... closer to indicating anacceptable state.ConclusionTherapy with infliximab has definite long-term clinical effi-cacy and safety in patients with AS. Patients who discon-tinue therapy are likely ... forassessment of their clinical disease state and the time to relapse (TtR). Relapse was defined as a Bath AnkylosingSpondylitis Disease Activity Index (BASDAI) value ≥ 4[10]and a physician's...

Báo cáo y học: " Varied sensitivity to therapy of HIV-1 strains in CD4+ lymphocyte sub-populations upon ART initiation" docx

... virus strainsdemonstrate varied sensitivity to therapy, as shown from studying two strains within a dual HIV-1 infectedindividual.BackgroundAntiretroviral therapy (ART) has proven to be successfulagainst ... 2007,24:1596-1599.25. Nabatov AA, Pollakis G, Linnemann T, Kliphuis A, Chalaby MI, Paxton WA:Intrapatient alterations in the human immunodeficiency virus type 1gp120 V1V2 and V3 regions differentially modulate ... Within the naïvesubset the V3 charge decreased systematically in allpatients (p = 0.05), indicating that characteristics suchas co-receptor usage may be involved in viral selectionfollowing initiation...

Báo cáo y học: "An intervention to improve paediatric and newborn care in Kenyan district hospitals: Understanding the context" ppsx

... study hospitals at baselineare illustrated in Additional File 1 and their location in Figure 1.Structure and service organisation Study hospitals had generators and for the main part wereable ... board. Thedistrict hospital often provides primary and inpatient careservices to a surrounding urban and nearby rural catch-ment area and, in principle, also provides referral care andinpatient ... have higher inpatient paediatric mor-tality. For indicators related to the process of hospital care,intervention group hospitals and control group hospitalsfared equally badly in general at...

Báo cáo y học: " Genetic characterization of wild-type measles viruses isolated in China, 2006-2007" doc

... of study design, data collection and analysis.Author Details1WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology & Genetic Engineering, National Institute ... derived by auto-mated sequencing and the BigDye terminator v3.0 chem-istry according to the manufacturer's protocol in bothsense and antisense strands by an automated ABIPRISM™ 3100 DNA Sequencer ... gen-otype H1 viruses compared to those isolates. ComparedChina vaccine strain, the 719th nucleotide of H1 wildstrains in China was changed from G to A in amino acidmutation from Ser to Asn....

Báo cáo y học: "Genetic and environmental influence on lung function impairment in Swedish twins" pot

... is shown for unadjusted data (% pred), data adjusted for packyears (PY) and data adjusted for pack years and respiratory symptoms (PY + SYM).Hallberg et al . Respiratory Research 2010, 11:92http://respiratory-research.com/content/11/1/92Page ... for pack years (PY) anddata adjusted for pack years and respiratory symptoms (PY + SYM).Hallberg et al . Respiratory Research 2010, 11:92http://respiratory-research.com/content/11/1/92Page ... smoking andsymptoms was found to be larger in men than in women. The total variance decrease was due to a reduc-tion attributed to genetic variance in women, and sharedenvironmental variance in...

Báo cáo y học: "Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis" pps

... release of pro-inflammatory cytokines and chem-okines, leukocyte accumulation, angiogenesis, and theANOVA: analysis of variance; CI: confidence interval; ELISA: enzyme-linked immunosorbent assay; ... these measures werethen analyzed as raw data [19]. According to data distributionand number of groups, a parametric (analysis of variance[ANOVA], t test) or non-parametric (Kruskal-Wallis, Mann-Whitney) ... area by inflammatory cells;3 = severe inflammation and massive invasion of adjacent tis-sues by pannus [17]. Other sections were scored for loss ofsafranin-O staining as a measure of cartilage...

Báo cáo y học: " New approaches to the modulation of inflammatory processes in airway disease models" pdf

... two to three years. Lyn kinase was also discussed as a novel target forinflammatory airway diseases.Keywords: airway diseases, animal models, chronic obstructive pulmonary disease, new approaches, ... cardiovascular interaction. In a study using human bronchial epithelial and sputumcells, Dr G Chipappara (Institute of Respiratory Patho-physiology, Italina national Research Council, Palermo,Italy) ... presented data on their PDE4 inhibitor, BAY 19-8004, in a smoking animal model and claimedgreater anti-inflammatory efficacy than with a steroid. Asta Medica (now known as Elbion) alsodescribed a new...

Báo cáo y học: "The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever" ppsx

... levels of uPA (c) and uPA receptor (uPAR) (d).uPATHBDPAIFactor VIIIuPA receptorFibrinogenDay 0Day 1Day 2Day 3Day 4Day 5Day 6(b) (a) ELISA - uPA urokinase plasminogen activator 024681012141618200123456Day ... chemokine ELISAsCytokine/chemokine levels in monkey sera/plasma wereassayed using commercially available ELISA kits according to manufacturer's directions. Cytokines/chemokines assayedincluded ... inducibleprotein-10, guanylate binding protein-1 and -2). Animals hadno detectable clinical illness at days 1 and 2, were feeding nor-mally, had normal physical activity patterns on days 1 and 2,and...

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