Báo cáo y học: " Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivators" pdf

... cited.Research Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivatorsAmber T Washington1, Gyanendra Singh2 and Ashok Aiyar*1,2AbstractBackground: Many pathogens ... con-centrations of paraquot, and (D) β-mercaptoethanol. Transactivation is expressed as a percent of expression under control conditions. Chelation of zinc, oxygen tension and oxidative stress ... activity, without any effect on Tat. Conversely, thioredoxin reductase 1 (TRR1) reduces Tat's function without any effect on EBNA1.Conclusions: We conclude that oxygen partial pressure and oxidative...

Báo cáo y học: "The immediate effects of local and adjacent acupuncture on the tibialis anterior muscle: a human study'''' pdf

... electromyography registra-tion of isometric dorsiflexion.To ensure the quality of the signal, we determined the rootmean square (RMS) of the rest position at 10% to 15% of the isometric contraction ... Neuropsychobiology and Motor Behavior, Department of Biomechanics, Medicine and Rehabilitation of the Locomotor System, School of Medicine – University of São Paulo, Ribeirão Preto (USP-RP), Avenida dos Bandeirantes ... integral part of Chinese medicine and is widely practiced in China and other countries [1] totreat conditions [2] and diseases such as myofascial painsyndrome [3], muscle spasticity after stroke...

Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx

... 8:53-54.9. Simpson GM, El Sheshai A, Rady A, Kingsbury SJ, Fayek M: Sertraline as monotherapy in the treatment of psychotic and nonpsychotic depression. J Clin Psychiatry 2003, 64:959-965.10. ... participated in its study and coordination. All authors read and approved the final manuscript.Author Details1Yonago Medical Corporation, Yonago Clinic, Yonago, Tottori, Japan, 2Yakumo Hospital, ... treatment of delusional depression: a pilot double-blind controlled study. J Clin Psychiatry 2000, 61:26-29.7. Furuse T, Hashimoto K: Fluvoxamine monotherapy for psychotic depression: the potential...

Báo cáo y học: "Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis" potx

... and curcumin and IL-1β on the viability and proliferation of primary chondrocytes in vitroEffects of resveratrol and curcumin and IL-1β on the viability and proliferation of primary chondrocytes ... itself.Figure 7 Effects of resveratrol and curcumin on IL-1β-induced inhibition of collagen type II and Sox-9 production in chondrocytesEffects of resveratrol and curcumin on IL-1β-induced inhibition of collagen ... phosphorylation and degradation, and inhibition of nucleartranslocation of NF-κB. The modulatory effects of curcumin and resveratrol on IL-1β-induced expression of cartilage specificmatrix and...

Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf

... as: Baune and Eyre: Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report. Journal of Medical ... 4:6http://www.jmedicalcasereports.com/content/4/1/6Page 4 of 4CAS E REP O R T Open AccessAnti-inflammatory effects of antidepressant and atypical antipsychotic medication for thetreatment of major depression and comorbidarthritis: ... which eventually led to a remission of pain and depression and tonormal general function.IntroductionPatients with major depression often suffer comorbidphysical disorders [1] of which some...

Báo cáo y học: "Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor" potx

... antibody levels. Pulmonary involvement wasassessed by computed tomography, forced vital capacity, and the ratio of carbon monoxide diffusion capacity tohemoglobin. Systolic pulmonary artery pressure ... particularly those of the dihydro-pyridine type such as nifedipine, are of major importance forthe treatment of Raynaud's phenomenon in SSc patients[15] and may have beneficial effects on cardiac ... deter-mined by Doppler echocardiography, and left ventricularejection fraction, by radionuclide ventriculography. Thecontrol subjects were healthy nonsmokers from the labora-tory staff.Study designPatients...

Báo cáo y học: "Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis" pps

... Intriguingly, RA patients responding to adalimumab treatment display ‘normalized’ levels of CD86 only on memory B cells, but not on naïve B cells, and reduced expression of FcγRIIB only on naïve ... low auto-antibody titres expressed higher levels of this receptor.  irdly, they also report an increased frequency of CD86, usually up-regulated upon activation, on memory and naïve B cells ... regulation of humoral responses, and that the defects in this system could contribute to the development of autoimmunity.  ere is evidence that FcγRIIB preferen-tially limits activation of high...

Báo cáo y học: "Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study" pptx

... their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation.Oncogene 2004, 23:9247-9258.56. Sylvester ... that of diclofenac and is humanspecific [34]. The main metabolite of aceclofenac is 4-hydroxy-aceclofenac. The other metabolites, namely diclofenac and 4-hydroxy-diclofenac, account for only ... ibuprofen, cause anti-inflammatory effects independent of COX activity and prostaglandin synthe-sis inhibition [45-47]. These effects are mediated through inhi-bition of certain transcription...

Báo cáo y học: "Gender-specific effects of HIV protease inhibitors on body mass in mice" ppt

... ovariectomy. Ritonavir did notinfluence weight gain in the ovariectomized female mice,suggesting an interaction at the site of action of ritonavir and ovariectomy in the ability of the two to ... properly cited.AIDS Research and Therapy 2007, 4:8 http://www.aidsrestherapy.com/content/4/1/8Page 8 of 8(page number not for citation purposes)Authors' contributionsMW conceived the study ... Relationship of serum adi-ponectin and leptin concentrations with body fat distributionin humans. Obes Res 2003, 11(3):368-372.10. Lonnqvist F, Arner P, Nordfors L, Schalling M: Overexpression of the...

Báo cáo y học: "Ex vivo effects of flavonoids extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behcet''''s disease" pptx

... IL-12 production may be partially mediated by the action of flavonoids through IL-4 induction as both IL-4 and IL-12 have shown to have antagonism effects. IL-4 exerts strong inhibition on Th1-mediated ... inflammatory processes involving the regulation of the synthesis of inflammatory cytokines (IL-2 TNF-α, IL-1β) and chemokines (CXCL8, CXCL10, CCL2). The effect of flavonoïds on cytokine modulation constitutes ... response by recruitment and activation of different cell types. The involvement of cytokines and chemokines in ABD pathogenesis is reflected by the increase of their concentrations in sera of...

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