... study may havebeen inadequate. It might take longer for IFN-γ levels todecline to negativity after treatment [21]. However, in high incidence countries where recurrent exposure iswidespread, ... responses remain robust even after antigenload declines with therapy. Interestingly, some individu-als had a transient decline in T cell responses shortly aftertreatment, but much higher responses ... phenomenon, and raises concernsabout efficacy of conventional preventive therapy in highincidence settings with recurrent exposure. Furtherresearch is needed to study T cell kinetics during...