... GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularlywithin the injured or diseased brain. In the case of GIF, the protein has many neuroprotective ... within the brain. Furthermore, the discovery and continued investigation of this brain-spe-cific MT isoform has led to intense interest in the roles of the entire MT family in the brain, with particularfocus ... (MT)-III:generation of polyclonal antibodies, comparison withMT-I+II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer’sdisease brains. J Neurotrauma 16,...