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Báo cáo y học: " Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1" docx

Báo cáo y học:

Báo cáo y học: " Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1" docx

... Access Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1Qian Wang, Tao Tao, Yanjing Zhang, ... without other RBSDV proteinsor RNAs. P6 recruits P9-1 to VLS by direct protein- pr otein interaction. This is the first report on the functionality ofRBSDV P6 protein. P6 may be involved in the process ... expressing bait protein BD -P6 and prey protein AD -P6 were transformed into Y1 87 and AH109 strains, respectively. Making surethere was no transcriptional activation or toxicity ofBD -P6 for yeast...
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Báo cáo y học: " An overview of treatment response rates to various anti-viral drugs in Pakistani Hepatitis B Virus infected patients" doc

... treatment response and the risk fac-tors of the currently recommended therapies againstHBV infecti on especially combination therapy of inter-feron and lamivudine in Pakistani isolates. These futureprospects ... increased severity and less response to interferontherapy. This poses a great challenge for physicians and researchers and further studies are needed to describe the outcome of the current therapies ... analogues are shown to beassociated with minimum side effects as compared to the standard INF and PEG-INF therapies. These i ncludeshort term adversed effects like myopathy, neuropathy and lactic acidosis...
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Báo cáo y học: " A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions" pptx

... sites in Akv-2XY were inserted between the 5'LTR and gag and between the env and the 3'LTR. (b) The Akv -Y provirus contained IRES-EYFP in the U3 region of the LTR. (c) The Akv-2XY provirus ... clones of GC4 infected by Akv -Y and Akv-2XYFigure 5Flow cytometry analysis of clones of GC4 infected by Akv -Y and Akv-2XY. The profile of AYGC.2A2 was representative of all Akv -Y infected GC4 ... Nils, Conroy Jeffrey, Hamilton Greg, Hindle AnnaKatherine, Huey Bing, Kimura Karen, Law Sindy, Myambo Ken,Palmer Joel, Ylstra Bauke, Yue1 Jingzhu Pearl, Gray Joe W., Jain AjayN., Pinkel Daniel,...
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Báo cáo Y học: Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe pdf

Báo cáo Y học: Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe pdf

... glutathione–Sepharose beads and after washing in lysis buffer the proteins bound to the beads were analyzed by SDS/PAGE and Western blotting using anti-GST Ig (lanes 1 and 2) and anti-Ha Ig(lanes 3 and 4). (B) ... expresses Ntp1p and Tps1pfused at their C-terminus to Ha6H and GST epitopes,respectively, and in both cases the synthesis is regulated bytheir own genomic promoters. The Tps1p fusion protein isactive ... sugar to play its diverse functional roles during the life cycle.Consequently, the study of the enzymes involved in trehalose metabolism and the subtle regulation of theiractivities at the molecular...
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Báo cáo y học: "Self-rated health showed a consistent association with serum HDL-cholesterol in the cross-sectional Oslo Health Study" pptx

... could in part be explained by the difference in exposure time of factors influencing SRH. In young people, some negative factors may not yet have had time to severely or permanently influence ... used only to identify the type of lipids. In men (top panel) LDL- and HDL-cholesterol, as well as TG concentration increased from the young (30 years) to the middle age group (40 and 45 years). ... health rating alternatives ‘poor’ and ‘not very good’ were grouped together as ‘Poor’, thus forming three groups to be used in the correlation analyses: Poor, Good and Very good. The sex and age...
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Báo cáo y học: "Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease" ppsx

... cells in pathogen-induced chronic inflammatory joint diseases. Any inflammation will cause the induction of chemokine and cytokine production in several tissue-associated cells in the joint, including ... stimulatory signal leads neither to the release of cyto-toxic effector molecules from CTLs, such as perforin and Table 2Interferon-γ production by cytotoxic T lymphocyte lines after incubation ... co-stimulation of cytotoxic T lymphocyte (CTL) lines by Lip-OspA can be inhibited by anti-Toll-like receptor (TLR)-2 monoclonal antibodyDirect co-stimulation of cytotoxic T lymphocyte (CTL) lines by Lip-OspA...
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Báo cáo y học: "Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians" potx

... microsatellitedetermine the variable number of aspartic acid residues in the amino-terminal end of the asporin protein. Asporin binds directly to the growth factor transforming growth factor beta and inhibitsits ... genotyped the samples and participated in the design and analysis of the study, MP-S, ML and JJG-R evaluated the patients, and AG coordinated the study and participated in itsdesign and analysis.Acknowledgements The ... by affected joint and by sex.Our results, together with reports from the United Kingdom and Greece, indicate that the stretch of aspartic acid residues in asporin is not an important factor in...
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Báo cáo y học: "Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data" ppsx

... seen in preterm infants exposed to indomethacin prior to delivery [27,28]. These complications are thought to berelated to the extent to which the individual NSAID selectivelyinhibits cyclooxygenase ... drugs, systemic lupus erythematosus and pregnancy. J Rheumatol 1998, 15:607-610.63. Lindquist NG, Ullberg S: The melanin affinity of chloroquine and chlorpromazine studied by whole body autoradiography.Acta ... age and birthweight to unexposed infants whose mothers did have RA.These preliminary findings suggest that the maternalunderlying disease or factors other than exposure to tumornecrosis factor...
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Báo cáo y học: "Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis" docx

... well as the repletion kinetics ofswitched MemB in the blood and their migration into joints arelinked to inflammatory activity. In the following sections, we willdiscuss the impact of these ... cellnumbers in another biopsy study [23]. In summary and accord-ing to the recently formulated 'roadblock hypothesis' [34], his-tology data after RTX draw the picture of an ongoing processof ... 2Histological preparations from RA synovitis in the early B cell reconstitution phase after RTX. Haematoxylin-eosin staining and immunohistochemistry for synovial B cells during the early peripheral...
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Báo cáo y học: "Progression of metastatic castrate-resistant prostate cancer: impact of therapeutic intervention in the post-docetaxel space" pps

... growth to prostate cancer cells.Interestingly, however, in mo del systems they may beinhibited by antiandrogens targeted to the ligand-bindingdomain, such as MDV3100 (see below) [20]. Hypotheti-cally ... thought to be derived from synthesis of the androgens directly in prostate cancer cells due to anupregulation of the enzymes necessary to synthesizeandrogens such as testosterone and dihydrotestostero ... of other signaling pathwaysmayplayaroleintheemergenceofCRPC.Theinterac-tion of endothelin-1 (ET-1) with the G -protein coupledendothelin-A (ETA) receptor has been implicated in car-cinogenesis,...
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