báo cáo khoa học: " Opiate users'''''''' knowledge about overdose prevention and naloxone in New York City: a focus group study" doc

báo cáo khoa học: " Opiate users'''' knowledge about overdose prevention and naloxone in New York City: a focus group study" doc

... specifically naloxone; 2) understanding and perceptions of naloxone; 3) potential comfort level with naloxone administration; and 4) feedback about increas-ing the visibility and desirability of a naloxone ... dopesickness, and fear of police. All of these areasreveal some benefits and challenges to naloxone trainingas a critical arena for overdose prevention, and offerimportant insights for improving overdose ... otherwiseremain disconnected. Opiate users' strong feelings about withdrawal symptomspost -naloxone also indicates that they may ignore warn-ings against continued opiate consumption after an over-dose...

Báo cáo khoa học: "bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study" pptx

... retrieve data frominaccurate patient charts, and pathology divisions, at least in our institutions, lack an appropriate database, whichwould facilitate the access to patient charts using pathol-ogy ... of patients in terms of pri-mary diagnosis and location of tumor and first metastasis.Mean age at initial diagnosis was 43 years, ranging from16 to 74 years, with a median of 42 years. Mean ... regimens thatincluded the following drugs: dacarbazine (DTIC), car-mustine (BCNU), verapamil, cisplatin and tamoxifen, in varying combinations and for one to five treatment cycles.One patient...

báo cáo khoa học: " How to integrate individual patient values and preferences in clinical practice guidelines? A research protocol" pptx

... that enable and facilitate patient involvement in medical decisionmaking. In this study, patient preference is defined as theappraisal of an individual who is informed and knowl-edgeable about ... probabilities and severity of theeffects and risks of interventions, and about process and outcome aspects of healthcare. For example, a choicemaybemadebetweenasurgicalorapharmaceuticalapproach ... Mulley A, Ruland C, Sepucha K, Sykes A, Whelan T: International Patient DecisionAids Standards (IPDAS) Collaboration. Developing a quality criteriaframework for patient decision aids: online international...

Báo cáo khoa học: "INTEGRATING MULTIPLE KNOWLEDGE SOURCES FOR DETECTION AND CORRECTION OF REPAIRS IN HUMAN-COMPUTER DIALOG*" potx

... which pattern matching, syntactic and semantic analysis, and acoustic analysis can be helpful in detect- ing and correcting these repairs. We use pattern matching to determine an initial set ... of varying lengths, it pulled out 500 as possibly containing a repair and missed 97 sentences actually containing a repair. Of the 500 that it proposed as containing a repair, 62% actually ... detection and correction of repairs by combining pattern matching, syntactic and semantic analysis, and acoustics. This paper extends work reported in an earlier paper *This research was supported...

báo cáo khoa học: " Sexual and injection-related risks in Puerto Ricanborn injection drug users living in New York City: A mixed-methods analysis" doc

... stage forcontinued syringe sharing within this group. Despiteample access to free and sterile injection supplies in NYC, sharing paraphernalia is mostly an actioninformed by habits, trust and ... 8:28http://www.harmreductionjournal.com/content/8/1/28Page 9 of 11Additionally, we categorized anyone below 30 years ofage as a young IDU.Data analysis examined differences in sociodemo-graphics, sexual and injection-related risks, and diseaseoutcomes ... migrants.Seventy-nine percent were monolingual Spanishspeakers.Table 2 presents factors associated with past-yearunprotected sex with a casual/exchange partner and receptive syringe sharing. In bivariate analysis,...

Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in ﬁbrinolysis and plasmin-induced cell detachment and apoptosis docx

... Montes R, Paramo JA, Angles-Cano E & Rocha E(1996) Development and clinical application of a new ELISA assay to determine plasmin-alpha2-antiplasmincomplexes in plasma. Br J Haematol 92, ... decrease in plasmin formation, to a decrease in plasmin bindingor to a combination of the two. We demonstrate thatboth mAb 34D3 and mAb A1 0.2 inhibit plasminbinding to cells (Fig. 5A) and ﬁbrin ... kringles. Thus, in Lys-plasminogen and plasmin, kringles 1 and 4 act as independent and complementary domains, both able to supportbinding and activation. We conclude that Glu- ⁄ Lys-plasminogen...

Báo cáo khoa học: GlnK effects complex formation between NifA and NifL in Klebsiella pneumoniae docx

... protein NifA in combination with the alternativer54-RNA polymerase [3,4]. In the free-living Klebsiellapneumoniae, Azotobacter vinelandii and Azoarcus sp. B H72,NifA transcriptional a ctivity ... Molecular Clon-ing: a Laboratory Manual, 2nd edn. Cold Spring HarborLaboratory Press, New York. 36. Berger, D.K., Narberhaus, F. & Kustu, S. (1994) The isolatedcatalytic d omain of NIFA, a bacterial ... (5¢-CACACAGGAAACAGAATTCCCGGG-3¢, sense primer (NifLE-coRI); 5¢-CAATGTCCTGAAGCTTACATAAGGCTTCAC-3¢, antisense primer (NifAHindIII). The 3.1 kb PCRproduct was cloned into t he EcoRI and HindIII...

Báo cáo khoa học: Selectivity of pyruvate kinase for Na+ and K+ in water/dimethylsulfoxide mixtures docx

... K+thatcouldbeassayedin100% water, K+induced a strong activation that exhibitedsaturation kinetics; Na+induced a relatively small enhance-ment of activity that was far from saturation. In water/dimethylsulfoxide ... (10 lM).Assay of pyruvate kinase activityThe formation of pyruvate was measured at 25 °Cinacoupled system with lactate dehydrogenase and NADH[30]. In water or in the binary water/dimethylsulfoxidesystem, ... Sodium-potassium-activatedATPase of mammalian brain regulation of phosphatase activity.Biochim. Biophys. Acta 382, 437–456.27. Swann, A. C. (1983) Brain (Na+,K+)-ATPase. Opposite eﬀects ofethanol and dimethyl...

Báo cáo khoa học: The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides pot

... vivomeasurements.MATERIALS AND METHODSCell cultureHuman cell lines HEK293 (embryonal kidney), 15PC3(prostate cancer), MiaPacaII (pancreatic carcinoma), T24(bladder carcinoma), HeLa (cervical carcinoma) and HTB82 ... methods, at least 90% transfection ef®ciency wasobtained, and the cells displayed little variation in stainingintensity. All cell lines showed a similar uptake and distribution, as shown in Fig. ... ®nding that antisense ODNs can bevery effective in inhibiting gene expression in the brain [44±46]. In both fetal and adult b rain, t he main 1.2-kb RNaseH2 mRNA can not (or hardly at all)...

Báo cáo khoa học: Kinetic hybrid models composed of mechanistic and simpliﬁed enzymatic rate laws – a promising method for speeding up the kinetic modelling of complex metabolic networks pptx

... fastequilibrium maintained among the mononucleotides,dinucleotides and trinucleotides by adenylate kinase and guanylate kinase, respectively. This increase in AMP or GMP is accompanied by enhanced degrada-tion ... face ofbiochemistry over decades – is currently considered toAMPNADAMPNADHATPGMPXMPIMPXanthosineInosineHypoxanthineGuanineGuanosineAdenineAdenosineAdenylo-succinateXanthineR1PR1P ... do notinclude all reactions that have been reported in theTable 5. Ranking of saturation parameters for hepatocyte purinemetabolism. Average ranking of saturation parameters according totheir...

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