... human and mouse mitotic centro-mere-associated kinesin (MCAK) (Fig. 4) [17–19]. Kine-sin family proteins generally contain the motor domain in the N- or C-terminal of the primary sequence, and the 01234567812345roundRecovery ... predicts the direction of walking on micro-tubules. MCAK belongs to the Kin I subfamily and itsmotor domain, unlike most kinesins, is in the interior of the protein. Moreover, the protein localizes ... [4], the P-selectin receptor[8] and a-glucosidase [29]. With the exception of the last two, the in vivo molecular targets for these effectshave yet to be elucidated. Interestingly, the bindinganalysis...