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báo cáo khoa học: " Improving introspection to inform free will regarding the choice by healthy individuals to use or not use cognitive enhancing drugs" doc

báo cáo khoa học:

báo cáo khoa học: " Improving introspection to inform free will regarding the choice by healthy individuals to use or not use cognitive enhancing drugs" doc

... not for citation purposes)Harm Reduction JournalOpen AccessCommentary Improving introspection to inform free will regarding the choice by healthy individuals to use or not use cognitive enhancing ... path into and to transcend the objective/subjective barrier and the mind/body problem.Whatever the fate of these specific hypotheses, discussion of cognitive enhancing drugs for healthy individuals ... Because the mind is subtle and individual, the cost-benefit ratio islikely to vary on an individual basis. Cognitive enhancing drugs intended for healthy peopleought to be drugs of choice. Informed...
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Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx

Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx

... against the final coordinates) due to the poor quality of the maps, andrefinement with refmac5 [29] stalled at R-factors of 26 and30%. This may be due to real disorder in the crystal as the mean ... the mean B-factor from the refinement was rather high(78.5 A˚2) – as was the Wilson B-factor (77 A˚2). It shouldbe noted that the data did not show signs of twinning andother possible ... between the flap subdomain and the active siteis analogous to the third metal, Mn2+, found inMtSTP [9]. In order to bind the metal ion, the flapdomain moves away from the core and the main...
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Báo cáo khoa học:

Báo cáo khoa học: "Improving Decoding Generalization for Tree-to-String Translation" docx

... Generalization for Tree -to- String Translation Jingbo Zhu Tong Xiao Natural Language Processing Laboratory Natural Language Processing Laboratory Northeastern University, Shenyang, China Northeastern ... was trained on the target-side of the bilingual data and the Xinhua portion of English Gigaword corpus. The beam size for beam search was set to 20. The base feature set used for all sys-tems ... solution, the most representative work is the forest-based translation method (Mi et al. 2008; Mi and Huang 2008; Zhang et al. 2009) in which a packed forest (forest for short) structure is used to...
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Báo cáo khoa học:

Báo cáo khoa học: " Improving Machine Learning Approaches to Coreference Resolution" potx

... throughout the paper. Unlessotherwise noted, reported differences are at the 0.05 level or higher. The chi-square test is not applicable to F-measure.is guided solely by inspection of the features ... required to determine the reasonfor this.Moreover, the Hand-selected Features produce the highest scores posted to date for both the MUC-6 and MUC-7 data sets: F-measure increases w.r.t. the Baseline ... reported to date on these data sets for the full NP coreference problem.1 The rest of the paper is organized as follows. Insections 2 and 3, we present the baseline corefer-ence system and explore...
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Báo cáo khoa học:

Báo cáo khoa học: "Improving Tree-to-Tree Translation with Packed Forests" potx

... beconfusing by just using a span to refer to a node. In addition,some nodes will often have the same labels and spans. There-fore, it is more convenient to use an identity for referring to anode. The ... the effectiveness of our ap-proach. We concatenated the small corpus weused above and the FBIS corpus. After remov-ing the sentences that we failed to obtain forests,2Note that even we used ... rule. Then, the de-coder runs on the translation forest. We use the cube pruning method (Chiang, 2007) to approxi-mately intersect the translation forest with the lan-guage model. Traversing the...
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báo cáo khoa học:

báo cáo khoa học: " Improving eye care for veterans with diabetes: An example of using the QUERI steps to move from evidence to implementation: QUERI Series" ppsx

... Subsequently, this information was used to identify how the PRSS might be tailored to function ateach site. It also was used to provide a platform for dis-cussing the potential advantages or disadvantages ... extracted for this subset to determine the status of those in the high-risk group, such as whether avisit was made within the recommended timeframe. The plan was for the eye clinic to use this information ... check-out forms were used at the two sites can- not be fully assessed due to incomplete informationabout the number of patients or patient visits while the forms were in use. Discussion The QUERI...
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Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

... to be less likely, because LRP1has been shown to be not regulated by cellular choles-terol levels [33], and therefore cannot account for the observed increased binding of [125I]TC-PCSK9 to HepG2 ... this range. The calculated Kdvalue for PCSK9-D374Y binding to the high-affinitysites was 125 ± 20 nm. Other investigators havereported an apparent Kdfor binding of PCSK9-D374Y to the ECD of ... binding of PCSK9 to the low-affinity form of LDLRs is followed by aslow conformational change of the ligand–receptorcomplex to the higher-affinity state, whereas this con-formational transition...
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Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: photosynthetic electron transfer from photosystem I to NADP+ doc

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: photosynthetic electron transfer from photosystem I to NADP+ doc

... one-electronreduced form, the semiquinone, because the midpointpotential for reduction of the oxidized state to the semiquinone, Eox ⁄ sq, is more negative than that forreduction of the semiquinone to the ... cofactor in the modulation of the redoxpotentials of the Clostridium beijerinckii flavodoxin.Glutamate-59 is not responsible for the pH dependencybut contributes to the stabilization of the ... potentials. Theymight be interpreted as being caused by a modificationin the accessibility of the flavin, but more generallycan be explained by a conformational change in the orientation of the interacting...
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Tài liệu Báo cáo khoa học: Identification of differentially expressed genes of the Pacific oyster Crassostrea gigas exposed to prolonged thermal stress docx

Tài liệu Báo cáo khoa học: Identification of differentially expressed genes of the Pacific oyster Crassostrea gigas exposed to prolonged thermal stress docx

... function, and changes in the expres-sion of genes from these clusters can be used to formulate hypotheses as to how different tissues andwhole organisms respond to particular biotic or abioticstresses. ... France). Sequences were then analyzed using BlastXalgorithm available from the National Center for Biotech-nology Information (NCBI) and the EST sequences werethen submitted to its dbEST and GenBank ... gigas) were exposed to 25 °C for 24 days(controls to 13 °C) to explore the biochemical and molecular pathwaysaffected by prolonged thermal stress. This temperature is 4 °C above the summer seawater...
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Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx

Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx

... exception offormaldehyde, none of the aldehydes affects the absorbanceof PAR. The data for the reaction of MT with formalde-hyde were corrected for the absorbance changes in the absence of ... ofthese aldehydes for the biological effects of ingestedethanol and lipid peroxidation, respectively.In order to explore whether or not acetaldehydereleases zinc from other zinc–sulfur coordination ... by activating the transcription factor Nrf2 [24]. Nrf2translocates to the nucleus when released from the pro-tein Keap1, a zinc metalloprotein with Zn–SCysco-ordination and the sensor for...
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