báo cáo khoa học: " Predictors of HIV infection and prevalence for syphilis infection among injection drug users in China: Community-based surveys along major drug trafficking routes" pps

... 1 of 11(page number not for citation purposes)Harm Reduction JournalOpen AccessResearch Predictors of HIV infection and prevalence for syphilis infection among injection drug users in China: ... characteristics and risk behaviors associ-ated with HIV positive injecting drug users in Xinjiang,China. J Infect 2007, 54(3):285-290.19. Wu Z: Recent trends of injecting drug use and related HIV infection ... this community-based survey to assess the prevalence of HIV and syphilis and predictors for HIV infections.MethodsStudy sitesThis study was conducted in three sites along major drug (heroin) trafficking...

Báo cáo khoa học: Roles of adenine anchoring and ion pairing at the coenzyme B12-binding site in diol dehydratase catalysis pptx

... cobalamin-bind-ing site [18] and an adenine-binding pocket [21] for Ado-Cbl. A modeling study using X-ray structures suggestedthat the tight binding of AdoCbl to both of these sitesinduces ... chain OHgroup of Sera224 and N3 of the adenine ring of thecoenzyme adenosyl group is important for activation of the Co–C bond in the absence of substrate as well.On the other hand, ion pairing ... structure of the diol dehydratase–adeninylpentylcobalamin com-plex revealed that the adenine moiety of adenosylcobalamin is anchored in the adenine-binding pocket of the enzyme by hydrogen bonding of...

Báo cáo khoa học:" Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection" pptx

... (BAL and US1).d not determined.Kinetic of the expression of p24gag in supernatants of cotton rat cell clones after HIV- 1 infectionFigure 2Kinetic of the expression of p24gag in supernatants of ... condoms' for the prevention of HIV infection: evaluation of novel agentsagainst SHIV(89.6PD) in vitro and in vivo. Aids 2001,15:1563-1568.28. Bourne N, Bernstein DI, Ireland J, Sonderfan AJ, Profy ... thiscontinues to be a major obstacle for studying HIV- 1 infection and pathogenesis, as well as for theurgent development and evaluation of effective anti -HIV- 1 therapies and vaccines. Previously,...

Báo cáo khoa học: " Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection" pdf

... (BAL and US1).d not determined.Kinetic of the expression of p24gag in supernatants of cotton rat cell clones after HIV- 1 infectionFigure 2Kinetic of the expression of p24gag in supernatants of ... detection in the supernatant of infected cells, [2]detection of episomal viral cDNA in infected cells, [3]demonstration of viral DNA integration into the genome of the cells, and [4] production of infectious ... thiscontinues to be a major obstacle for studying HIV- 1 infection and pathogenesis, as well as for theurgent development and evaluation of effective anti -HIV- 1 therapies and vaccines. Previously,...

Tài liệu Báo cáo khoa học: Role of hydroxyl group and R/S conﬁguration of isostere in binding properties of HIV-1 protease inhibitors docx

... foundrotatedtoeachother.TheanglesbetweenplainsofP3¢phenyl rings are 98° for OE and SE inhibitors, and 38° for OE and RE inhibitors. The S3¢ groups of OE and REinhibitors having a similar orientation phenyl rings form asimilar ... in uence onconformation of inhibitor main chain. Thus, differentinhibitors differ not only in t he binding afﬁnity, bu t a lso in the degree o f freedom of the inhibitor inside the bindingtunnel. ... distance of projections of opposite Sdatoms of M et46 and Met146).Ó FEBS 2004 HIV- 1 Protease Inhibitors (Eur. J. Biochem. 271) 4457Inhibitor binding. The inhibitor OE b inds into the p roteasebinding...

Tài liệu Báo cáo khoa học: Effect of sequence polymorphism and drug resistance on two HIV-1 Gag processing sites pdf

... vari-ation in HIV- 1 protease, Gag p7 and p6, and proteasecleavage sites within Gag/Pol polyproteins: amino acid substitu-tions in the absence of protease inhibitors in mothers and childrenÓ ... residues of the S1¢subsite (R ¼ 0.98). The ﬁt of various P1¢ residues into theS1¢ binding site of HIV- 1 PR is shown in Fig. 2. The resultsTable 3. Processing of peptides representing wild-type and ... Copeland, T.D., Wondrak, E.M. & Oroszlan,S. (1991) Comparison of the HIV- 1 and HIV- 2 proteinases usingoligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins....

báo cáo khoa học: " Seroprevalence of HIV, hepatitis b, and hepatitis c among opioid drug users on methadone treatment in the netherlands" ppt

... hepatitis C virus infection in injection and noninjection drug users in Italy. Clin Infect Dis2003, 37:33-40.32. van Dam M: National Institute for the Environment and Health,department of Personal ... Effectiveness of methadonetreatment in reducing HIV risk behavior and HIV seroconversion among injecting drug users. AIDS 1999, 13:1807-1818.27. European Monitoring Centre for Drugs and Drug Addiction: ... countries. However, in Eastern Europe and out-side of Europe, HIV rates have increased in recent years[27] and suggest an increasing incidence of HIV infec-tion among people who inject drugs [28]....

báo cáo khoa học:" Predictors of health status do not change over three-year periods and exacerbation makes difference in Chronic Obstructive Pulmonary Disease" ppsx

... significantly higher for patients in stage IV than for patients in stages I and II, and also for patients in stage III than for patients in stage I and for patients in stage II than patients in stage I. ... increased risk of worsening in the SGRQ total score and activity domain. Our findings are in accord with Lin et al. [11], who found by multiple linear regression that the BODE index was associated ... downloaded,printed and distributed freely for any purposes (see copyright notice below).Articles in HQLO are listed in PubMed and archived at PubMed Central. For information about publishing your...

báo cáo khoa học:" Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study" ppt

... Activity of Daily Living (ADL) [10]assesses the ability of patients to perform the daily activ-ities of bathing, dressing, toileting, transferring, conti-nence and feeding. This index correlates ... assessed by the Katz index of Activity of Daily Living (ADL) [10] and a cognitive score based onthe individual components of the Lawton index of DailyLiving (IADL) [11], date of admission to the ... dependence) and the best was 6 (complete independence).The cognitive score includes the individual compo-nents of the Lawton index of Daily Living: ability toDaubin et al. Health and Quality of Life...

Báo cáo khoa học: " Evidence of HIV-1 adaptation to host HLA alleles following chimp-to-human transmission" pdf

... against foreign antigensplays a major role in exerting selective pressure on anti-genic proteins, including those of HIV- 1. The activation and characteristics of the immune responses against ... Paiardini M, Pandrea I, Lederman M, Sodora D: Under-standing the benign nature of SIV infection in natural hosts.J Clin Invest 2007, 117:3148-3154.7. Pandrea I, Ribeiro RM, Gautam R, Gaufin T, ... higher in the HIV ancestral branch than in therest of the tree (Table 3). The difference was significantonly for HLA A*6801, with a ω of 3.5 in the HIV ancestralbranch and 1.6 in the rest of the...

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