... low-
income countries among 111 editorial board members in
five leading medical journals, including the Annals of
Internal Medicine, BMJ, JAMA, the Lancet and the NEJM.
Each of the five journals ... with the
British Medical Journal (BMJ) and The Lancet providing
four times more coverage of diseases affecting primarily
poor countries than the New England Journal...
... containing atRE in the presence of
1m
M bipyridine (B) and liposomes containing atRE, in the presence
of 1 m
M bipyridine and 6 mM FeSO
4
(C). The generated retinoids
were analyzed by HPLC. The ... contribute to
providing chromophore to melanopsin to maintain
their light sensitivities. The expression and function of
RPE65c in other cell types in the retina remains to...
... residues directly involved in ligand
binding, presumably abolishing the interaction with
signaling partners. The remaining mutations alter
amino acids located outside the ligand-binding pocket
and ... pro-
tein kinase B (PKB)]. In AKT, a cysteine substitution
of the corresponding R25 in the pleckstrin homology
(PH) domain also results in loss of function [16,17],
thereby...
... reaction of the luciferin ⁄ luciferase mixture, energy
donor (ATP) and oxygen results in the emission of light.
The intensity of the bioluminescence was detected using a
luminometer, and the mitochondrial ... McClain DA,
Litwin SE et al. (2002) Insulin signaling coordinately
M. F. Essop et al. Metabolic gene switching in murine female heart
FEBS Journal 274 (2007) 5278–5...
... integrin-dependent
cell volume sensing and signaling integrates into the
overall context of insulin signaling. Similarly, sensing
of glutamine-induced hepatocyte swelling by integrins
feeds into ... hepatocyte swelling [12,13], insu-
lin-induced hepatocyte swelling is registrated by the
integrin system, leading to a Src-dependent activation
of the p38-type MAPK and thereby inhibit...
... the densities correspond to the N- and
C-terminal helices of the c ring, respectively. The
C-terminal helices show a clear handedness, and two
of the rings face in the opposite direction in the
membrane ... of the
ion-binding site. Therefore, the c ring of A. woodii has
only 10 membrane-buried negative charges that are
essential for binding the ion and also for...
... Follistatin, Chordin and Noggin
[12]. These proteins are antagonists of BMP and other
members of the TGF-b family, binding to and inhibit-
ing these signaling molecules from binding to their
receptors ... protein 2 in the early devel-
opment of Xenopus laevis. Mech Dev 52, 357–370.
7 Fainsod A, Steinbeisser H & De Robertis EM (1994)
On the function of BMP-4 in patterning...
... within the intermembrane space, and the
proteolysis must therefore represent a loss of 2 kDa
from the N-terminus. Given there are seven arginine
and lysine residues spread through the N-terminal
stretch ... most of the protein
components are integral in the membrane, most of these mitochondrial pro-
teins behave as if they have a-helical transmembrane domains, rather than...
... categories.
M
ethod
C
* there is telephone and the books on the desk.
Eb: The word in the beginning of the part which
should be replaced.
Ee: The word in the middle or the end of the part
which ...
word and the one preceding/ the targeted word
and the one following/ the targeted word and the
two preceding/ the targeted word and the two fol...
... development of
the game situation. In the Figure 5, we have illus-
trated this in the same way we did for the case of
interruption. The left hand side of the solid line is
lower than that of the ... that interruptions raise the importance score
gain by reacting sharply to the sudden increase of
the importance score.
Abbreviation
If the two most import...