Báo cáo y học: " Randomised controlled trial of the clinical and cost effectiveness of a specialist team for managing refractory unipolar depressive disorder" ppt

Báo cáo y học: "Randomized controlled trial design in rheumatoid arthritis: the past decade" docx

... expected in the near future. The FinRaCo (Finnish RA Combination Therapy) [56] trial introduced the paradigm of ‘treating to target’: allowingtherapeutic titration in those not achieving a prespecified ... over the past decade in trial design in RA. These include the following:ã Establishment of a clear regulatory path to demonstrateefficacy of a new therapeuticã The use of pure placebo beyond ... changes in HAQ-DI (from baseline to 6 and12 months) were –0.54 in patients who received combinationtherapy for the entire trial compared with –0.30 in thosereceiving combination therapy only during...

Báo cáo y học: "Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65" pptx

... ananti-inflammatory type [26]. This relative deviation of the cytokine response, caused either by decreased Th1-typecytokines and/ or by enhanced Th2-type cytokines leading to the regression of an autoimmune ... anti-inflammatory cytokines over pro-inflammatory cytokines in response to Bhsp65 To test and compare the T cell proliferative and cytokine response to the disease-related antigen Bhsp65 of Celastrus-treated ... treatmentfacilitated the secretion of the anti-inflammatory cytokine IL-10over the pro-inflammatory cytokine IFN-γ, resulting in the over-all skewing (immune deviation) of the cytokine response to ananti-inflammatory...

Báo cáo y học: "CD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro model" pdf

... domain linked to a glycosyl-phosphatidylinositol anchor showed no significant change in Table 1Effect of anti-CD47/IAP, anti-TSP-1, and anti-SIRPα on mechanically induced changes in human articular ... articleCD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro modelMahmoud Orazizadeh1,3, Herng Sheng Lee2,3, Bianca ... signal-regulatory protein -alpha (SIRPα) by human articular chondrocytes and molecular associa-tions of CD47/IAPExpression of thrombospondin-1 (TSP-1) and signal-regulatory protein- alpha (SIRPα) by human...

Báo cáo y học: " Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study" potx

... cigarette smoking associates with reduced BMI and BF in patients with RA and heavy smoking associates with lower muscle mass. Smoking cessation appears to associate with increased BMI, BF, and waist ... identify potential associations of smoking with body weight and composition of RA patients. Methods A total of 392 patients (290 females) with RA wereassessed for body mass index (BMI), body fat ... energyexpenditure (REE) and enhanced muscle catabolism [2]. Suchchanges may lead to rheumatoid cachexia (that is, involuntaryloss of fat-free mass [FFM] with a proportional increase of body fat [BF]) in...

Báo cáo y học: "Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study" pdf

... for statistical analysis.Results Dietary intake and fatty acid profilesThe mean dietary intake of total energy, carbohydrate, protein and fat is shown in Table 2. Compared with the Swedish FoodRecommendations ... Engvall IL, Elkan AC, Tengstrand B, Cederholm T, Brismar K, Haf-strom I: Cachexia in rheumatoid arthritis is associated with inflammatory activity, physical disability, and low bioavailableinsulin-like ... AN, Papavasiliou EC, Lourida ES, Alamanos Y, KostaraC, Tselepis AD, Drosos AA: Atherogenic lipid profile is a featurecharacteristic of patients with early rheumatoid arthritis: effect of early...

Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps

... clearly separated by the proximity of the cells to the joint space and the bone respectively, alignment of the chondrocytes along the arcades of Benninghoff [29] and by the appearance of hypertrophic cells. ... differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transferAndre F Steinert1,2, Benedikt Proffen1, Manuela Kunz1, Christian Hendrich1, ... compare the effects of BMP-4 and BMP-2 expression on chondrogenesis of primaryMSCs and to investigate whether levels and extent of hyper-trophy in vitro is influenced by the choice of transgene.Materials...

Báo cáo y học: " Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays" pptx

... original work is properly cited.Method Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arraysMelissa H Pespeni*1, ... as: Pespeni et al., Restriction Site Tiling Analysis: accurate dis-covery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays Genome Biology 2010, 11:R44 Pespeni ... withindel polymorphisms, we used these signal intensity cut-Figure 1 Restriction site tiling analysis identifies polymorphisms and genotypes individuals by hybridization to a custom microarray. Fifty...

Báo cáo y học: " Stress response regulators identified through genome-wide transcriptome analysis of the (p) ppGpp-dependent response in Rhizobium " docx

... showing the rsh mutant to be (p)ppGpp-deficient.However,duetothesensitivityoftheassay,thepre-sence of trace amounts of (p)ppGpp in the rsh mutant,possibly resulting from the presence of an ... high up in the hierarchy of interconnected regulators in E. coli, controlling the expression and/or function of many other regulators such as Lrp, the cAMP receptor protein CRP, the inte-gration ... prominent role for the alarmone in the general stress response of R. etli during free-livinggrowth and symbiosis [30]. In order to obtain new insights into the molecularbasis of adaptat ion of...

Báo cáo y học: "Platysma motor branch transfer in brachial plexus repair: report of the first case" pot

... purposes)Journal of Brachial Plexus and Peripheral Nerve InjuryOpen AccessCase report Platysma motor branch transfer in brachial plexus repair: report of the first caseJayme Augusto Bertelli*Address: ... AbstractBackground: Nerve transfers are commonly employed in the treatment of brachial plexus injuries. We report the use of a new donor for transfer, the platysma motor branch. Methods: A patient ... period of only 3 years, which may be a shortinterval for cortical integration of the hypoglossal to the musculocutaneous nerve transfer. The current study con-trolled the patient for 8 years...

báo cáo khoa học: "Randomised controlled trial of tailored interventions to improve the management of anxiety and depressive disorders in primary care" pdf

... 6:75http://www.implementationscience.com/content/6/1/75Page 6 of 8 STUD Y PRO T O C O L Open AccessRandomised controlled trial of tailored interventions to improve the management of anxiety and depressive disorders in primary careHenny Sinnema1*, ... 21:1103-1112.doi:10.1186/1748-5908-6-75Cite this article as: Sinnema et al.: Randomised controlled trial of tailored interventions to improve the management of anxiety and depressive disorders in primary care. Implementation ... depressive disorders in general practice in the Netherlands.Methods/designObjectives The primary aim of this RCT is to det ermine the effec-tiveness of tailored interventions to improve the imple-mentation...

Báo cáo y học: " Randomised controlled trial of the clinical and cost effectiveness of a specialist team for managing refractory unipolar depressive disorder" ppt

... 10:100http://www.biomedcentral.com/1471-244X/10/100Page 5 of 11 STUD Y PROT O C O L Open Access Randomised controlled trial of the clinical and cost effectiveness of a specialist team for managing refractory unipolar depressive disorderRichard ... general practitioners and p sychother-apy services in England and Wales.2. Euroqol 5 D [32] as a measure of quality of li fe and costs from health and social care and societyperspectives measured ... group the participant has been randomised to at the end of 12months treatment. At the end of the study, theseguesses will be compared against chance.Statistical analysisStatistical analysis for...

Báo cáo y học: " Simultaneous monteggia type I fracture equivalent with ipsilateral fracture of the distal radius and ulna in a child: a case report" docx

... Monteggia injuries of the elbow and ipsilateral distal radius and ulna fractures are very rare. Case Presentation: A unique case of a type I Monteggia fracture equivalent with ipsilateral fracture ... Mon-teggia injury with distal diaphyseal fracture of the radius [5]; 11 cases of Monteggia fracture dislocation with frac-ture of the ipsilateral radius and ulna [6]; three epiphysealfractures (distal ... showing a Monteggia type I equivalent elbow injury before and after internal fixation.Radiographs showing a Salter-Harris type II distal radius fracture before and after wiringFigure 2Radiographs...

Báo cáo y học: " Some ABCA3 mutations elevate ER stress and initiate apoptosis of lung epithelial cells" pptx

... as: Weichert et al.: Some ABCA3 mutations elevate ER stress and initiate apoptosis of lung epithelial cells. Respiratory Research2011 12:4.Submit your next manuscript to BioMed Central and take ... the ER, caused significant increase of the ER stress and early and late apoptosis markers in the A549cells (Figure 4, 5 and 6). The ER stress caused by R280Cmutation was slightly lower and ... consequence of the ER stress caused by com-plete or partial ER retention of the ABCA3 protein.Discussion ABCA3 mutations cause surfactant deficiency and fatalrespiratory distress syndrome in full-term...

Báo cáo y học: "Randomised controlled trial of school-based humanistic counselling for emotional distress in young people: Feasibility study and preliminary indications of efficacy" pot

... properly cited.ResearchRandomised controlled trial of school-based humanistic counselling for emotional distress in young people: Feasibility study and preliminary indications of efficacyMick ... controlled trial of school-based humanistic counselling for emotional distress in young people: Feasi-bility study and preliminary indications of efficacy Child and Adolescent Psy-chiatry and Mental ... trial comparing six weeks of humanistic school-based counselling versus waiting list in the reduction of emotional distress in young people, and to obtain initial indications of efficacy.Methods:...

Báo cáo y học: " Asymmetric histone modifications between the original and derived loci of human segmental duplications" pptx

... genes and pseudogenes does not, however,fully account for the asymmetry in the profile of histone modifications. Conclusion: The first systematic analysis of histone modifications between segmental ... parental SDs(Tables 2 and 3). The asymmetric distribution of genes, however, cannot fullyaccount for the asymmetric profiles of histone modifications described above. Firstly, the asymmetrical pattern ... R105Research Asymmetric histone modifications between the original and derived loci of human segmental duplicationsDeyou ZhengAddress: Institute for Brain Disorders and Neural Regeneration, The Saul...

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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống chuyên đề điện xoay chiều theo dạng Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Nghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt nam Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDE Phát hiện xâm nhập dựa trên thuật toán k means Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúng Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tin Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP