báo cáo khoa học: " Intervening in global markets to improve access to HIV/AIDS treatment: an analysis of international policies and the dynamics of global antiretroviral medicines markets" potx

... as: Waning et al., Intervening in global markets to improve access to HIV/AIDS treatment: an analysis of international policies and the dynamics of global antiretroviral medicines markets Globalization ... distribution, and reproduction in any medium, provided the original work is properly cited.Research Intervening in global markets to improve access to HIV/AIDS treatment: an analysis of international policies ... designed and coordinated the study, participated in data cleaning and data analysis, and was the lead author on this paper. ED, LS and SM contributed to data analysis and writing of the manuscript....

Báo cáo khoa học: "Recombination in West Nile Virus: minimal contribution to genomic diversity" ppt

... Kunjin virus) sequences. The 6 distinct lineages are maintained and are delineated by red brackets. Branch lengths are proportional to distance (the number of nucleotide changes), and the distance ... a change in the topology of the trees, but a decrease in the distance, or number of changes, which separates the daughter (AnMg798) and minor parent (KN3829) sequences from each other in the recombinant ... wasmaintained to allow confirmation of the recombinationevent by examining the similarity existing between the minor parent and recombinant sequences represented bydifferences in the overall topology...

Báo cáo khoa học: "Mortality in over 350,000 Insured Swedish dogs from 1995-2000: I. Breed-, Gender-, Age- and Cause-speciﬁc Rates" pptx

... withexact denominators (the sum of each animal'stotal time of observation) and all deaths in the numerator. If a dog left the insurance during ayear for reasons other than death, it was ... especiallyestimates of survival to certain ages, is infor-mative for current and prospective owners of abreed and for veterinarians and researchers.Comparing similarities and differences in pat-terns of mortality ... important to take into account the age pat-tern of disease and possible differences in agedistribution across groups when examiningcompeting causes of death, as in this and the companion paper...

báo cáo khoa học: " Overweight in the Pacific: links between foreign dependence, global food trade, and obesity in the Federated States of Micronesia" ppt

... quan-tities, and these dietary changes led to dramaticallyincreased prevalence of overweight and obesity. The following section examines the role of the tuna indus-try in Micronesian behavior and health. ... amap of Micronesia). Spain was the first nation to colonizeMicronesia; they arrived in 1886 and controlled the islands until Germany took over in 1899. The Japanesearrived 15 years later and ... Health at the 6th Open Meeting of the Human Dimensions of Global Envi-ronmental Change Research Community in Bonn, Germany. Lastly, I would like to thank Francis X. Hezel, SJ and an anonymous...

Tài liệu Báo cáo khoa học: Changes in purine speciﬁcity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2 pptx

... the adenine and guanine of cAMP and cGMP as primary ligands.Previous experiments investigating cGMP binding to GAF domains of mammalian PDEs were designed on the basis of the mPDE2 GAF domain ... FEBS to the mammalian PDE GAF domains. cAMP is the ligand for these cyanobacterial tandem GAF domains, and cAMP binding results in stimulation of the C-terminal catalytic domain [7–9]. To date, ... is the major interaction site for the adeninemoiety. In b1, an arginine residue (Ile417 in rPDE2)binds to N1 and a threonine (Ser419 in rPDE2) inter-acts with N7 and the N6amino group. The...

Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc

... significant binding of bis-ANS to any of the particles, with the exception of T45S, which bound asmall amount of bis-ANS, increasing, by twofold, the emission of the probe (Fig. 7B). M88V and WT ... different from those of other simple icosahedralviruses [13]. The main chain of the protein subunit foldsinto a five stranded antiparallel b-sheet (strands bC–bG)facing the interior of the phage particle, ... hydrophobiccore (M88V) and the other in the protein–RNA interaction(T45S), decrease the stability of the capsid. Our findingsilluminate the role of packing in the icosahedral lattice of the virus capsid.Experimental...

Tài liệu Báo cáo khoa học: "Experiments in Semantic Classification" pptx

... dictionary defining the meanings of words, without any human intervention (say by scanning text mechanically, and sorting and evaluating the results obtained mechanically). In practice one ... for other parts of speech have been and can be constructed. An important fea- ture of this method of indicating the meanings of words is indeed that it can be applied to any kind or class of ... making can depend on them. There seems to be no way of giving rules for determining whether one word “makes one think” of another or not, and there are similar difficulties in defining the...

Tài liệu Báo cáo khoa học: Histones in functional diversification Core histone variants pdf

... site of H2B interaction, bind to the minor groove on the out-side of the superhelix (Fig. 3A). Thus, N-terminal tailsare involved in deciding the DNA–histone interactions, and to keep an intact ... variants of H2B and H1 are known, which playimportant roles in spermatogenesis. How can smallchanges in the primary sequence of one of the histonesintroduce a change in the overall structure of ... well as in regions ﬂanking HMR loci. Theseregions prevent the ectopic spread of the repressorproteins Sir2 and Sir3 into the ﬂanking euchromatin,as Sir proteins are found to extend beyond the...

Tài liệu Báo cáo khoa học: Changes in rat liver mitochondria with aging Lon protease-like activity and N e-carboxymethyllysine accumulation in the matrix doc

... with two intense signals of 70 and 50 kDa, while the bands at 60 and 150 kDavanished.With oxyblot (Fig. 4C), antibodies stained carbonylatedproteins mainly in band ranges of 30–60 and 70–120 ... 1)contained 14 bands intensely stained over an apparentrange of 10–170 kDa, with the most prominent band at60 kDa (lane 1). In the 27-month-old preparations (lane 2)only eight main bands are stained, ... damagedprotein and/ or a decrease in the amount of this protein in the matrix. We have not detected any signiﬁcant modiﬁca-tion in the amount of this protein in the matrix. We canconclude that the decrease...

Tài liệu Báo cáo khoa học: " Multimodal In-Car Dialogue" docx

... opera-tors of the dialogue manager which implementconversation acts (Blaylock and Allen, 2005). The model is then specialized to a domain byinheriting and instantiating domain-speciﬁc types and instances ... sentence planning rules in the PATE system to build the templates, and a set of XSLT trans-formations to yield the output strings. Output in German and English is produced by accessing dif-ferent ... extension of the Information State Up-date approach (Traum and Larsson, 2003) to the multi-modal setting.Novel aspects in turn planning and realizationinclude the comprehensive modeling in a sin-gle,...

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