Báo cáo khoa hoc:" Soy isoflavones increase preprandial peptide YY (PYY), but have no effect on ghrelin and body weight in healthy postmenopausal women" pdf

... intake and body weight, despite significantly increased preprandial PYY concentrations. The findings indicate that PYY is nota major factor in the regulation of body weight. Prepran-dial ghrelin ... and only one study investigated effectsof isolated isoflavones on total ghrelin concentrations[19]. In addition, no long-term randomized controlledstudies have investigated whether changes in ... treatments and compared to baseline (wk4 - wk0; interaction treatmentvs. time, P = 0.634). Effect of isoflavone consumption on PYYDuring isoflavone consumption, PYY concentrationsincreased...

Tài liệu Báo cáo khoa học: DNA modiﬁcation with cisplatin affects sequence-speciﬁc DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

... [10]. In addition, interactions of the p53 protein with cer-tain response elements can be controlled by changes in DNA topology inducing formation of non-B DNAstructures within the binding sites ... moststrongly affected by DNA cis-platination, containsGG, GGG and AG motifs in one strand and GG and GTG motifs in the other, thus offering not only thehighest total number of reactive motifs among ... eliminate thesedifferences, the effects of DNA cis-platination on theprotein–DNA interactions were always normalizedwith the intensity of the retarded band resulting fromprotein binding to...

Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx

... Protein A Sepharose, in the presence of non-ionic detergent. These antigen–antibody complexeswere collected, and after rigorous washing in nonionicdetergent-containing buffer and elution of ... this interaction is not detectedby examining it indirectly through TnrA–DNA bindingassays [9,10,18]. Constitutive binding of GS to TnrA in the GlnK-deﬁcient strain provides an explanationfor ... reported that the DNA-bindingdomain of TnrA is located on its N-terminus, whereasthe C-terminus is responsible for GS binding [10]. Sixamino acids required for this interaction on the C-termi-nus...

Báo cáo khoa học: Transcript proﬁling reveals diverse roles of auxin-responsive genes during reproductive development and abiotic stress in rice pdf

... of growth and development in plants. Sev-eral recent discoveries in auxin biology, including theidentification of F-box proteins as auxin receptors, have contributed to our understanding of the ... 2009)doi:10.1111/j.1742-4658.2009.07033.xAuxin in uences growth and development in plants by altering geneexpression. Many auxin-responsive genes have been characterized in Ara-bidopsis in detail, but not in crop plants. ... ofauxin-responsive genes in reproductive development and abiotic stress signaling in rice.Results and DiscussionIdentification and overview of auxin-responsivegenesPreviously, we identified and...

Báo cáo khoa học: The calpain 1–a-actinin interaction Resting complex between the calcium-dependant protease and its target in cytoskeleton doc

... a-actinin, either in direct contact or in acomplex including the two proteins. In conclusion, our study proves the interaction betweena-actinin and calpain 1 and locates binding motifs withinregions ... calpain binding site in theC-terminal domain of smooth muscle a-actinin.Involvement of the C-terminal domain of ask in Calp1 binding In order to locate the region responsible for the binding ... 10 min-autolysed Calp1(h) and increasing ask concentrations or between coated ask and increasing Calp1 concentrations (inset). Binding was monitored at405 nm using biotin-labelled proteins...

Báo cáo khoa học " Lentinula edodes enhances the biocontrol activity of Cryptococcus laurentii against Penicillium expansum contamination and patulin production in apple fruits " ppt

... laurentii and can also contribute directly to thecontrol of patulin contamination. Moreover, LF23 extracts are not onlynon toxic for human health but better still, they can have a positive healthy effect ... demonstrated and only one study reports the inhibiting effect exerted by phytoalexinslike quercetin and, to a lesser extent, resveratrol, against patulinbiosynthesis but without considering ... °C and 90% of relative humidity. In order to evaluate the antagonistic activity of LS28 and LF23 on in vivo mould extension and patulin production in semi-commercialconditions 5 apples, inoculated...

báo cáo khoa học: " A cluster randomized trial to improve adherence to evidence-based guidelines on diabetes and reduce clinical inertia in primary care physicians in Belgium: study protocol [NTR 1369]" potx

... literature on diffusion, dissemination and sustainability of innovations in health servicedelivery and organization. London 2004.74. Carroll C, Patterson M, Wood S, Booth A, Rick J, Balain S: A con-ceptual ... including those whoreport on clinical inertia, have defined three principalsources for non-adherence to evidence-based guidelines and clinical inertia: physician factors, patient factors, and office ... for clinician education include an increasedunderstanding of principles guiding clinical care or aware-ness of specific recommendations for the patient popula-tion using a treatment and shared...

báo cáo khoa học: " Assessing the impact of the Australia-United States Free Trade Agreement on Australian and global medicines policy" pps

... Commerce, International Trade Admin-istration. In Pharmaceutical Price Controls in OECD Countries. Implica-tions for US Consumers, Pricing, Research and Development and InnovationWashington DC; 2004. ... property protection and weakening of medi-cines clinical and cost-effectiveness evaluation and/ or ref-erence pricing, necessarily involves a weakening of anation's social and economic fabric, ... threenominated trade lawyers will have the power to interpretcompliance with obligations in the AUSFTA. Article21.2(c) contains what is known in international trade lawas a non-violation nullification...

Báo cáo khoa học: "Continuously assessed right ventricular end-diastolic volume as a marker of cardiac preload and fluid responsiveness in mechanically ventilated cardiac surgical patients" pdf

... Available online http://ccforum.com/content/9/3/R226R232group makes any conclusion regarding possible differences in any of the variables between responders and nonrespondersdifficult.ConclusionDespite ... orLVEDA index. Some investigators questioned the clinical sig-nificance of correlation between RVEDV index and continu-ously assessed CI, but Durham [19] and Nelson [30] and theirgroups demonstrated ... or PCWP, as indi-cated by the weak correlation between baseline value ofLVEDA index and the resulting increase in SVITD following fluidloading (Fig. 2b). These findings are in accordance...

Tài liệu Báo cáo khoa học: a-Defensins increase lung ﬁbroblast proliferation and collagen synthesis via the b-catenin signaling pathway doc

... data indicating that a-defensin-1 and a-de-fensins-2 induce an increase in the protein content ofcyclin D and that quercetin inhibits the a-defensin-induced increase in cyclin D protein content ... and a-defensin-2 induced increases in the phosphorylationof GSK3b and b-catenin activation and that inhibitionof b -catenin activation prevented a-defensin-inducedproliferation and collagen ... levels and collagen release into culture medium induced by a-defensin-1 and a-defen-sin-2. Knocking-down b-catenin using small interfering RNA technologyalso prevented a-defensin-induced increases...

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