... PD.
In this population-based study, we investigated whether
sequence variations in the PINK1 gene play a role in the
late-onset form of PD. A recently described variation
(Q115L) of the PINK1 gene ... mutation
screening.
Conclusion
Investigations of other genes involved in the mitochon-
drial pathway of the PINK1 gene are necessary to evaluate
the e...
... measurements of the reference ceramic
then 32 measurements of the sample) was obtained for each sample.
The absorbance spectrum, represented as a log value(1/R), was ob
-
tained by averaging these ... LGS
measurement was obtained, on the same longitudinal axis at the pe-
riphery of the tree. Chemical analyses and shrinkage measurements
were performed on these extreme str...
... HAD inhibitors. To
check for covalent modifications of the enzyme, the
effect of the inhibitor on the molecular mass value of
HAD was measured; instead of an adduct increase, or
no change, the ... destroys
the information on the size of the protein and the connectivities of the pep-
tide fragments, but it has no size limit for protein digestion. In contras...
... 10 min.
The affinity of elastin for NE or Pr3 was assessed by
adding a constant concentration of enzyme to increas-
ing concentrations of elastin, stirring for 10 min,
centrifugating the suspensions ... suppress the elas-
tase-inhibitory capacity of alpha 1-proteinase inhibitor
in vitro. J Clin Invest. 66, 987–995.
24 Bieth JG (1984) In vivo significance of kinetic const...
... synthesis.
In this type of synthesis, units of recorded speech
are appended. By using recorded speech, many of
the voice qualities of the person recording the
speech remain in the resulting ... segments of speech. Appending larger the units of
speech results in smoother, more natural sounding
synthesis, but requires many hours of recording,
often by a traine...
... protein band, thus pointing to
the absence of a covalently bound flavin moiety in the
recombinant product. Moreover, as in the case of
the plant l-galactono-1,4-lactone dehydrogenase [12],
the ... cell signaling.
L-AA is therefore involved in a wide array of crucial
physiologic processes, including: biosynthesis of colla-
gen and other hydroxyproline ⁄ hydroxylysine-c...
... multifunctional protein that plays a key
role in binding chitin, and thus in participating in the
structuring of the organic framework, at the same time
as finely interacting with the mineral phase. It is ... be essential for the control of
the biomineral formation [1]. In particular, it is
assumed to interact in different ways with the mineral
phase at the na...
... underspecifi-
cation formalism can be compact, i.e. in the worst
case, the USR of a set of readings become exponen-
tially large in the number of scope-bearing operators.
In the case of RTGs, this worst case ... dis-
joint, i.e. neither dominates the other.
We take the hard backbone of D to be the ordinary
dominance graph B(D) = (V, E
T
E
D
) obtained by
removin...
... trig-
gering receptor kinase activity and signaling pathways
involving the binding of ezrin to ezrin–radixin–moesin
proteins, and thus actin cytoskeleton binding and Ras
activation. HGF elicits metastatic ... [22,23]. The rather short cytoplasmic tail
of CD44 binds to ankyrin and ezrin–radixin–moesin
proteins, providing a link to the cytoskeleton, as well
as to merlin, which abr...
... with these findings, CT26 cancer cells significantly increased LFA-1 expression in non-
hypoxic avascular micrometastases at their earliest inception within hepatic lobules in vivo; and angiogenesis ... not for citation purposes)
Background
During the earliest stages of the hepatic metastasis proc-
ess, microvascular arrest and residency of disseminated
cancer cells results in...