Báo cáo khoa hoc:" Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210" pptx
Báo cáo khoa hoc:" Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210" pptx
... 1 of 11(page number not for citation purposes)Journal of Negative Results in BioMedicineOpen AccessResearch Despite WT1 binding sites in the promoter region of human and mouse nucleoporin ... identified in the promoter region of the human GP210 gene, experimental modulation of WT1 expression did not influence expression of GP210. Therefore, WT1 is probably not regulating GP210 expression. Instead, ... targetgenes for WT1. This could include the gene for GP210, butpresumably not other nucleoporins. In the only previ-ously reported nucleoporin promoter region, of mouse nup358, several binding sites...
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Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx
... possibility; however, the inhibition of PI3K with LY294002 and the inhibition of FASwith cerulenin caused the disappearance of droplets and prevented the formation of new droplets duringexposure to ... the b-oxidation of FFAs; and ⁄ or(d) NPs could modulate the expression of proteinsinvolved in the retention of lipids in LDs, such as lip-ases or other LD-associated proteins. We have shownthat ... the mechanisms involved in the down-regulation of fatoxidation by NPs require further investigation.Fat accumulation and the down-regulation of the b-oxidation of FFAs were induced in PC12 cells...
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Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx
... effect of bending strainThere are several indications of a redistribution of the strains exerted on the oligonucleotide by the bend: partial unstacking of some adenine, thymine and guanine bases and ... SREfos and SREGfos,on the one hand, and SREGGfos, on the other hand,consists in the distinct strains acting on the helix ply of these oligonucleotides. Conversion between the bent and linear ... those resultingfrom the formation of a sharp bend in the DNAoctamer duplex (HMG box) due to binding of the human SRY–HMG protein. The decrease in tem-perature results in striking similarities...
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Báo cáo khoa học: Key substrate recognition residues in the active site of a plant cytochrome P450, CYP73A1 ppt
... mutagenesis of the involve-ment of some of these residues in the docking and catalysis of cinnamic acid. The impact of the active site mutations on the binding and metabolism of cinnamic acid ... positioning of CA. Mutation of all arginines led to a significant loss in protein stabilitysuggesting that they are involved in protein fold structurerather than binding of the substrate. The overall ... affect the binding of cinna-mate and the coupling of the hydroxylation reaction [9].This effect was probably due to a direct interaction of itsside-chain with the aromatic ring of the substrate....
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Báo cáo khoa học: A novel G-quadruplex motif modulates promoter activity of human thymidine kinase 1 docx
... experimentally demon-strated. In the case of the c-MYC promoter, it wasshown that the purine-rich strand of DNA in the nuclease-hypersensitive region of the promoter canadopt different intramolecular G-quadruplex ... G-quadruplex forming sequences, had changes in the presence of G-quadruplex -binding ligands in twodifferent human cell lines [36].A role of G-quadruplex motifs in the transcription of specific genes ... change in the promoter activity of pTK1 suggests involvement of the G-quadruplex motifformed by TKQ1 in regulating TK1 expression. Inter-estingly, to the best of our knowledge, TKQ1 is the first...
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Báo cáo khoa học: " Radiation-induced skin injury in the animal model of scleroderma: implications for post-radiotherapy fibrosis" ppt
... is not a suitable model to study the effects of radi-ation in case of scleroderma. Further studies are requiredto elucidate the role of FBN-1 in controlling TGF-β1 sign-aling in TSK mouse. The ... 0.05).Consistent with the expected association of transforming growth factor beta-1 (TGF-β1) with latetissue injury, levels of the cytokine were significantly higher in the skin of the C57BL/6 mouse compared ... skin and correlated them with the level of tissue injury and fibrosis. Both free (active) and total TGF-β1 was higher in C57BL/6 mouse skin at all time pointsafter radiation compared to the...
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Báo cáo khoa học: " Intensity Modulated Radiotherapy (IMRT) in the postoperative treatment of an adenocarcinoma of the endometrium complicated by a pelvic kidney" pot
... that, in case of a relapse and need for new chemotherapy regimens, maintaining asmuch functioning marrow as possible presents anotheradvantage of using IMRT. Roeske and cols have shown the main ... irradiatedto a dose of 40 Gy or one third to a dose of 28 Gy.As noted on the DVH (figure 3) these parameters havebeen respected in the present case. The literature does not define the optimal treatment ... fine RT technique can help avoiding. Intensity Modulated RT(IMRT) enables the treatment of the target volume while protecting normal tissue. It thereforereduces the incidence and severity of...
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báo cáo khoa học: "Evolutionary relationships based on in the Sativa group of Oryza isozyme data" docx
... established early in the history of domestication of rice and maintained because of selfing and selection.part. Both axis allowed for the distinction of the positive and negative ... shows the results on the first plane of an analysis including the Asianstrains of O. rufipogon and the collection of 40 varieties of O. sativa. The variabi-lity of wild ... strains, irrespective of life forms. It includes the 3 strains originating in New Guinea with South Asian affinity.2) O. rufipogon, Chinese (CA) : From China, including...
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báo cáo khoa học: " Placenta increta causing hemoperitoneum in the 26th week of pregnancy: a case report" ppt
... Trophoblastic islands in the myometrium(haematoxylin and eosin, original magnification × 40).Figure 3 Fresh red blood cells in the rupture line of the uterine wall (haematoxylin and eosin, originalmagnification ... hemor-rhage, uterine rupture and inversion, and invasion of the urinary bladder, are all related to the site of placentalimpl antation, the depth of myometrial invasion, and the width of abnormally ... considered impossible to save the uterus, especially in terms of another possible preg-nancy. Because the quantity of intra-abdominal bloodremoved was considerable and the uterine rupture wasconsidered...
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Báo cáo khoa học: "Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus" pdf
... study.Conclusions: Together, the findings from this study have provided a detail profiling of the human membranetrafficking cellular genes and the mechanistic insight into the interplay of these host genes ... to the late endoso mesby this time point. The fluorescent staining was moreintense at the perinuclear region. The involvement of endosomal trafficking of internalized DENV particleswas further ... clathrin-coated pits and that actin polymerizationmay be involved in moving endocytic vesicles into cyto-sol after they are pinched off from the plasma mem-brane [58]. The actin -binding m...
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Từ khóa: Báo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngThơ nôm tứ tuyệt trào phúng hồ xuân hươngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ