Báo cáo khoa hoc:" Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts" pps

... 10 of 13RESEARC H Open Access Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohortsDavid W Ellison1*, Mehmet Kocak2, Dominique ... (OS) in four European trials.(a)PFSand(b) OS by trial. Black line = SFOP; red line =CNS9204; blue line = CNS9904; and green line = AIEOP.Ellison et al . Journal of Negative Results in BioMedicine ... its reproducibility and clinical significance. In a 3-phase study, we reviewed the pathology of 229 intracranial ependymomas from European trial cohorts of infants (2 trials - SFOP/CNS9204) and...

Báo cáo khoa học: Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover pptx

... formation, indicatingthat Sec14p and the two homologues act as inhibitors of Plb1p in vivo. This observation explains at least in part thelow Plb1p activity in wild-type cells. Interestingly, theinhibitory ... temperature of 37 °C[3]; and (b) cki1 prevents reincorporation of the majority of released free choline into PtdCho via the CDP-cholinepathway [6]. On the other hand, strains bearing the cki1mutation ... level of PtdChoturnover in the strain with intact PLD1 gene and analysis of the turnover products indicate that high PtdCho turnoverobserved in SFH2 and SFH4 overexpressing cells is linkedto...

Báo cáo khoa học: "Immunohistochemical localization of calcium binding proteins and some neurotransmitters in myenteric plexus of goat stomach" doc

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báo cáo khoa học: " Taking stock of current societal, political and academic stakeholders in the Canadian healthcare knowledge translation agenda" docx

... process of planning, produc-ing, disseminating, and applying existing or new research in decision-making" [44].Using these definitions, both agencies have establishedkey funding directives ... that remains between researchknowledge and healthcare practice. Indeed, the transla-tion of basic scientific knowledge into clinical studies and the translation of clinical studies into improvements ... in 1999, CIHR has increased itsfunding three-fold in clinical research and twenty-fold in health systems research supporting its knowledge transla-tion mandate [46]. Despite these funding increases,...

báo cáo khoa học: " Taking stock of current societal, political and academic stakeholders in the Canadian healthcare knowledge translation agenda" pptx

... examination research to highlight thecomplexity and intricacy of interpreting research in amanner that guides clinical decisions, particularly whenresearch calls accepted clinical practices into ... translation of basic scientific 'bench' discoveriesinto clinical studies and the translation of clinical studiesinto improvements in health care practices remain twomajor obstacles in the ... that remains between researchknowledge and healthcare practice. Indeed, the transla-tion of basic scientific knowledge into clinical studies and the translation of clinical studies into improvements...

Báo cáo khoa học: " Early changes of CD4-positive lymphocytes and NK cells in patients with severe Gram-negative sepsis" ppt

... Calandra T, Cohen J, International Sepsis Forum Definition of Infection in the ICU Consensus Conference: The internationalsepsis forum consensus conference on definitions of infection in the intensive ... of early changes taking place in the clinical setting of a septic host is of prime importance in order tounderstand the underlying pathogenesis. The majority of clini-cal studies do not provide ... distribution, and reproduction in any medium, provided the original work is properly cited.AbstractIntroduction Our aim was to define early changes of lymphocytes and of NK cells in severe sepsis and...

Báo cáo khoa học: "Marjolin''''s ulcers: theories, prognostic factors and their peculiarities in spina bifida patients" ppsx

... appearance of ulceredges.Figure 2 Marjolin’s ulcer with sinuses extending into the thigh and labia majora. One sinus was found in the anus, and another in the vagina. Note benign appearance of ulcer ... implantation,the co-carcinogen and the initiati on and promotion the-ory; these theories include trauma as an integral part of the process of the evolution of Marjolin’sulcers[2-9].The immunologically ... worker in developing programs suited to agrowin g population of spina bifida patients, especially in the low income countries. The author also sought todescribe atypical clinical presentation of...

Báo cáo khoa học: " Histopathological changes of testes and eyes by neutron irradiation with boron compounds in mice" pps

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Tài liệu Báo cáo khoa học: Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells pdf

... enrichment in iNOS activitywithin the particulate fraction of epithelial cells.Apical distribution of iNOS in intestinal epithelialcellsTo get more insight into the localization of iNOS in intestinal ... distribution of iNOS protein and activity in vitroThe distribution of iNOS protein in the cytosol and particulate fraction was examined in DLD-1 cellsexposed to cytokines. To determine the partitioning ... association of iNOS in vivo In order to determine the distribution of iNOS in intestinal epithelial cells in vivo, experiments were con-ducted in mice injected with bacterial ﬂagellin. Flagel-lin activates...

Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in ﬁbrinolysis and plasmin-induced cell detachment and apoptosis docx

... Llinas M (1988) Lysi-ne ⁄ fibrin binding sites of kringles modeled after thestructure of kringle 1 of prothrombin. Proteins 3, 85–96.20 Thorsen S (1975) Differences in the binding to fibrin of native ... in plasmin formation, to a decrease in plasmin bindingor to a combination of the two. We demonstrate thatboth mAb 34D3 and mAb A10.2 inhibit plasminbinding to cells (Fig. 5A) and fibrin (Fig. 5B) in ... 5)thus indicating accessibility and participation of bothK1 and K4 in firmly anchoring plasmin to fibrin and cell surfaces. Because the expanded Lys-form of plasminogen may be an intermediary in plasmin...

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