báo cáo khoa học: " Moving research into practice: lessons from the US Agency for Healthcare Research and Quality''''''''s IDSRN program" ppt
báo cáo khoa học: " Moving research into practice: lessons from the US Agency for Healthcare Research and Quality''''s IDSRN program" ppt
... number not for citation purposes)Implementation ScienceOpen Access Research article Moving research into practice: lessons from the US Agency for Healthcare Research and Quality's IDSRN programMarsha ... Interview protocols for AHRQ staff focused on their role in IDSRN, the under-lying rationale for the program, their perspectives onimplementing research into practice, and their views of IDSRN& apos;s ... answer two key research questions:1) Was IDSRN successful in supporting the operationaluse of research findings and moving research into prac-tice, either within IDSRN or externally? and 2) What...
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Tài liệu Báo cáo khoa học: Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus – biochemical characterization and homology modeling doc
... ribose and Ca2+ into the binding site ofSsCU-NH was performed using, as a starting reference, the position of the sugar and of the metal in the crystallo-graphic template 1YOE. The two ligands ... of the program, setting the highest level of optimization. The quality of the mod-els and their stereochemical properties were analyzed using the programs procheck [65] and prosaii [66], and the best ... against the PDB [57] database. A further search for suitable tem-plates was made with the servers SAM-T02 [58,59] and FUGUE [60] and gave the same results, therefore confirm-ing the correctness of the...
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Báo cáo khoa học: Sulfide : quinone oxidoreductase (SQR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity pdf
... Dueren, Germany). For cDNA synthesis, the first-strand synthesis kit for RT-PCR (Invitrogen) was used.Hybridization probe, cloning and heterologousexpressionStandard molecular and biochemical ... substrate other than sulfide and quinone, and, for the SQR from S. pombe, cyanide-independentactivity has been described [27]. However, the Kmvalues for sulfide and quinone of 2 mm reported for S. ... and other marine invertebrates, such as the ribbed mussel Geukensia demissa, are sulfide toler-ant [5], however, and can even use electrons from sulfide for mitochondrial ATP production [6]. The electrons...
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Báo cáo khoa học: Bacterial b-peptidyl aminopeptidases with unique substrate specificities for b-oligopeptides and mixed b,a-oligopeptides pptx
... activities of the two BapA enzymes for the firstfive peptides were quantified by HPLC of the residual substrate; the reactions of the other substrates were analyzed by measuring the formation of the dipeptide ... exchangechromatography and hydrophobic interaction chromatogra-phy according to the previously published procedure for the wild-type 3-2W4 BapA [17]. The two final steps of the protocol, the elution from the hydrophobic ... analysis of the purified enzymes 3-2W4 BapA and Y2 BapA. According to the gel, the molecular masses of the a-subunits and b-subunits were 26.6 kDa and 13.4 kDa, respec-tively, for 3-2W4 BapA, and 26.8...
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Báo cáo khoa học: A novel metallocarboxypeptidase-like enzyme from the marine annelid Sabellastarte magnifica – a step into the invertebrate world of proteases pdf
... glutamic acid from the peptide was observed and, after 60 min, the newC-terminus residues formed and tryptophan and ala-nine were further released, as shown by the trimmingscale: 1716, 1587 and 1329 ... isolated from marine invertebrates, and in not one case have the whole or extended sequences been disclosed. Thiswould be the case for the two CPAs and CPBs isolated from the hepatopancreas of the ... SmCPactivity The concentrations used in the assays were 329 nM for the enzyme SmCP and 0.1 mM for the substrate AAFP, at pH7.5 and 25 °C The enzyme, after EDTAtreatment and dialysis against metal-freebuffer...
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Báo cáo khoa học: Recent insights into cerebral cavernous malformations: the molecular genetics of CCM pot
... seemed confusing [1].Three CCM genes have been mapped and identifiedin the recent years. These molecular genetics data haveprovided useful information for clinical care of the patients and were ... vitro studies and in vivo CCManimal model studies have helped to unravel the func-tional roles of these proteins and are be the focus of the two accompanying minireviews by Faurobert and Albiges-Rizo ... in the next future to identify the molecular anomalies of CCM patients ‘without’mutations.Conclusions and future The recent identification of the three CCM genes is animportant step towards the...
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Báo cáo khoa học: Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138 pot
... the only other changes visible areshifts in the position of nevirapine for bothRT(Lys101Glu) and RT(Glu138Lys), with the biggestmovement observed for the drug in the latter mutant.Previous ... between the carb-oxyl of Glu138 and the inhibitor. It would thus beexpected that there is an accompanying reduction inbinding affinity for PETT-2 for the Glu138Lys muta-tion. In fact the EC50 and ... and the inhibitors [24]. Movementof the Lys101 side-chain away from the NNRTIpocket on mutation to glutamic acid, as observed for the nevirapine complex, would thus cause loss ofcontacts and...
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báo cáo khoa học: " A typology of practice narratives during the implementation of a preventive, community intervention trial" docx
... gained from the sub-jective meanings of the CDOs (gathered via field diary and interviews) and the concepts they use to understand theirpractice [21]; much of the CDOs' practice (and programimplementation ... ofvalue for adjusting the intervention were raised withinmemos and in meetings between the EcoPRISM research team and the PRISM research team. The PRISM research team also monitored PRISM process and ... positionthemselves in the telling of the story and the context of the story telling occasion [22] This approach to handling the data is consistent with the phenomenological aim ofunderstanding the...
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Tài liệu Báo cáo khoa học: "Automatic Collection of Related Terms from the Web" pptx
... from the compiled corpus.2. Selection by scoringTo select the top N (= 30) terms from the list Lby using a scoring function. For the scoring function of a term x, we use the following function, ... query. In case the query is a term, its hitis the number of pages that contain the term on the Web. We use the following notation.H(x)= the number of pages that contain the term x” The number H ... in Table 2 shows the result.S: the target term was collected by the system.F: the target term was removed in the filtering step.A: the target term existed in the compiled corpus,but was not...
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Báo cáo khoa học: A new phospholipase A2 isolated from the sea anemone Urticina crassicornis – its primary structure and phylogenetic classification pptx
... placozoans (Trichoplax), and mollusks (Cras-sostrea and Mytilus), and also in the only knownvertebrate PLA2, that of the sea lamprey (Petromy-zon marinus). Furthermore, the Asn27 PLA2s can ... Japan).RACE5¢-RACE and 3¢-RACE were performed on the RACE-ready cDNA prepared from previously isolated total RNAwith the GeneRacer Kit (Invitrogen, Carlsbad, CA, USA). For the 3¢-RACE reaction, the GeneRacer ... 37 °C for another 3 h. Cells were thenpelleted, and inclusion bodies were isolated. Refolding ofUcPLA2was performed following the protocol used for refolding of ammodytoxins [39]. The refolded...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ