Báo cáo y học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" ppsx
Báo cáo y học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" ppsx
... determine the direction of an effect. This applies to hypotheses C and D. Because (A) the number of applied changes is hypothesised to beinfluenced by the presence of the right conditions and (B)an ... organisa-tion, and external change agent support (for informationStudy model: hypothesised relations between conditions, applied changes and outcomesFigure 1Study model: hypothesised relations between conditions, ... available of 94% of the operating theatre productiv-ity teams, 82% of the pressure ulcer teams, 78% of the waiting list teams, 50% of the wound infection teams,41% of the medication safety teams, and...
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báo cáo khoa học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" doc
... applies to hypotheses C and D. Because (A) the number of applied changes is hypothesised to beinfluenced by the presence of the right conditions and (B)an increase in the number of applied changes ... organisa-tion, and external change agent support (for informationStudy model: hypothesised relations between conditions, applied changes and outcomesFigure 1Study model: hypothesised relations between conditions, ... available of 94% of the operating theatre productiv-ity teams, 82% of the pressure ulcer teams, 78% of the waiting list teams, 50% of the wound infection teams,41% of the medication safety teams, and...
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Báo cáo y học: "Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays" potx
... ARRHYTHMO, (b) CIRCADIAN CLOCK ASSOCIATED1, (c) LATE ELONGATED HYPOCOTYL, and (d) EARLY FLOWERING3. The top half of each panel displays the Watson strand and the bottom half the Crick strand. ... (At2g38325) and MIR390B (At5g58465) were reliably detected by the AtTILE1arrays, neither was found to exhibit a circadian rhythm (Addi-tional data files 1 and 2). On the other hand, the abundance of the ... used the Arabidopsis ATH1 array. In these studies, more than 75% of the protein coding transcripts assayed were found to cyclewhen driven by various conditions of photocycles and/ orthermocycles...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... Bouriotis1,21Department of Biology, Division of Applied Biology and Biotechnology, University of Crete, Greece;2Institute of Molecular Biology and Biotechnology (IMBB), Enzyme Technology Division, and the 3Institute ... replacement of Gly261 by Ala in mutantG261A resulted in an enzyme with slightly lower stability.On the other hand, in the double mutant G261A /Y2 69A the additional replacement of Tyr269 by Ala restores ... G261A/ Y2 69A designed on the basis of side-chain packing criteriafrom a modelled structure of the enzyme resulted in restor-ation of the energy of activation to the levels of the nativeenzyme and...
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Báo cáo Y học: Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides Binding mode of vitamin K derivatives pptx
... unambiguously clear, the posi-tions of the protons in the protein binding site wereautomatically assigned byFLEXX. In cases of ambiguities(hydrogens of the h ydroxyl groups, the N-bound proton of the ... orientation of the naphthoquinone ringsystem, i.e. the calculated protein–ligand complexes showtwo hydrogen bonds between the carbonyl oxygens of the quinones a nd the amide nitrogen of AlaM260 and the imidazole ... analysis theydetermined the binding free energy, enthalpy and entropy of the ubiquinone to the QB-site.Methyl substituted 1,4-naphthoquinones have gainedsubstantial i nterest a s they bind...
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Báo cáo y học: " Exploring the optimum approach to the use of CT densitometry in a randomised placebo-controlled study of augmentation therapy in alpha 1-antitrypsin deficiency" pptx
... and January 2007. Two of the authors of the manuscript (MW and CD) are employees of Talecris and participated in the design of the study, in the col-lection, analysis and interpretation of ... to the design of the study, in the analysis and interpretation of data, and drafting of the manuscript.AD was responsible for the Danish arm of EXACTLE and reviewing/contributing to writing the ... region.These data are of critical importance; not only do theyprovide information on the natural history of emphysemaprogression, but they may also influence the design and interpretation of future...
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Báo cáo khoa học: "Exploring the Sense Distributions of Homographs" docx
... replaced by the concordances of the instances of w1. Regarding the interpretation of the results,if the ratio between s3 and s4 should turn out tobe similar to the ratio between s1 and s2, then the influence ... can proba-bly be enlarged by increasing the size of the cor-pus. However, further investigations are neces-sary to verify this claim.With the approach based on the concordances of the homographs ... ±300, the number of correct cases (201)outnumbers the number of incorrect cases (63) bya factor of 3.2. Note that the increase of incorrectcases is probably mostly an artefact of the sparse-data-problem...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
... residue for the final family isgiven in Fig. S1. Fig. 3A shows the family of 40 structures and Table 1 contains a summary of statistical data indica-ting the quality of the 40 models and the average ... computers. Quality assessment of the structurePROCHECK[36] and PROCHECK-NMR [37] programs wereused to check the stereochemical quality of the peptidestructure and provide the elements of the secondarystructure, ... syndrome, inflammatory dis-eases, pre-eclampsia or preterm labour, anxiety and depres-sion and a potentially great number of other disorders.We have previously described the synthesis and the biological...
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Báo cáo Y học: Reconstructing the replication complex of AcMNPV pdf
... with2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k libraryor 1.0 lg of each plasmid of the overlapping lef library asdescribed by Passarelli ... aportion of the origin of replication hr5. Two-hybrid yeastconstructs were generated by PCR of each lef and insertioninto the EcoRI and XhoI sites of plasmids PJB4-5 and PEG202, respectively, using ... by insertion of PCR products into the BglII and PspAI sites of plasmid phsp70HAHisVI+ containing the 5¢ terminal amino acid sequence RYPYDVPDYARA. The sequence YPYDVPDYA constitutes the haemaggluti-nin...
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Báo cáo Y học: Optimizing the delivery systems of chimeric RNA . DNA oligonucleotides Beyond general oligonucleotide transfer ppt
... endosomes and be transported easily in the cytoplasm. Fourth, theyshould enter the nucleus easily. For transfection in vivo,thisis one of the most important hurdles. Finally, cytotoxity isanother ... problem. Only low or nontoxic deliverysystems could be used in humans. Therefore, we must testdifferent delivery systems on RDOs, and try to lower theircytotoxity and improve their efficiency.FUTURE ... (dioleoylphosphatidylethanolamine) has the ability to form nonbilayer phases and promote destabiliza-tion of the bilayer of the endosome membrane. DOPE isadded to cationic liposomes and other delivery systems...
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