Báo cáo y học: " Forefoot pathology in rheumatoid arthritis identified with ultrasound may not localise to areas of highest pressure: cohort observations at baseline and twelve months" ppt
Báo cáo y học: " Forefoot pathology in rheumatoid arthritis identified with ultrasound may not localise to areas of highest pressure: cohort observations at baseline and twelve months" ppt
... soon. Forefoot pathology in rheumatoid arthritis identified with ultrasound may not localise to areas of highest pressure: cohort observations at baseline and twelve monthsJournal of Foot and ... bursitis of the forefoot in patients with early rheumatoid arthritis. J Rheumatol 1998, 25:229-230. 1 Forefoot pathology in rheumatoid arthritis identified with ultrasound may not localise to areas ... detectable forefoot soft tissue pathology may be unrelated to peak forefoot pressures and suggest that patients with RA may biomechanically adapt to soft tissue forefoot pathology. In addition,...
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Báo cáo y học: " Autoantibody profile in rheumatoid arthritis during long-term infliximab treatment" pdf
... inflamed rheumatoid synovium and the local environment may favoursynovial RF production [40], we can speculate that thereduction in inflammatory lymphoplasmacytic infiltrate in rheumatoid synovium ... Arthritis with Concomitant Therapy Study Group: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy ... (according to ACR 20 criteria) in RF and anti-CCP antibody titreseither at baseline or at 78 weeks.Figure 1Changes in disease activity in 30 patients with rheumatoid arthritis at different times during...
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Báo cáo y học: "Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis-induced specific antinuclear and antiphospholipid autoantibodies without autoimmune clinical manifestations: a two-year prospective study" potx
... Prospectiveevaluation of the frequency and clinical significance of antineutrophil cytoplasmic and anticardiolipin antibodies in community cases of patients with rheumatoid arthritis. Rheu-matology (Oxford) ... TG autoantibodies at baseline. Patients with RAremained positive during infliximab treatment and at the 1-year intervals of methotrexate treatment. Only one patient(1 of 21, 4.8%) in the infliximab-treated ... role of the disturbance of the cytokine network in suchinduction has already been demonstrated for anothercytokine, interferon γ, inducing the development of autoan-tibodies in patients with...
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Báo cáo y học: "Homing chemokines in rheumatoid arthritis" doc
... with RA, infiltrating T and B lym-phocytes accumulate underneath the synovial lining layer and organize into lymphocyte aggregates with germinalcentres (GCs) [19–21]. These ectopic lymphoid ... predominant infiltratethe inflamed synovium, is consistent with their highly dif-ferentiated state [11–16]. These inflammatorychemokine receptors are prominently expressed oneffector T lymphocytes ... cells) that mediate a type 1inflammation such as RA. Interestingly, it has also beendemonstrated that the RA synovial memory CD4+T lym-phocytes express high levels of the chemokine receptorCXCR4,...
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Báo cáo y học: "B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response" docx
... comparison of patients positive and negative for RA-associated HLADRB1 alleles.Patients and methodsNinety-four patients with long-standing RA according to the 1987 American College of Rheumatology ... isotypes, and concentrations of circulatingimmune complexes. For details on standard laboratorytests and the flow cytometric analysis performed, seeSupplementary material.The determination of ... Jr: Somatic mutation and CDR3lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals. JClin Invest 1995, 96:831-841.17. Randen...
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Báo cáo y học: "Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis" pps
... RA-induced and RA therapy-inducedhyperhomocysteinemia to CHF risk in RA has yet to becompletely elucidated.Inflammatory cytokines In patients with overt CHF, levels of inflammatory cytokines(TNF-α, ... effects of inflammatory cytokines (and rheumatoid arthritis therapies) on the myocardia of rheumatoid arthritis patients areincompletely understood.IntroductionUnique cardiac complications of rheumatoid ... Activation of the immune system and inflammatory activity in relation to markers of atherothrom-botic disease and atherosclerosis in rheumatoid arthritis. JRheumatol 2002, 29:875-882.105. Yxfeldt...
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Báo cáo y học: "Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs." pot
... Progression and repair in radiographs of hands and forefeet in early rheumatoid arthritis. J Rheumatol 1995, 22:1048-1054.7. Rau R, Herborn G: Healing phenomena of erosive changes in rheumatoid arthritis ... Feldmann M, etal.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J ... A, et al.: Min-imal clinically important difference in radiological progression of joint damage over 1 year in rheumatoid arthritis: preliminaryresults of a validation study with clinical experts....
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Báo cáo y học: "Epigenetic modifications in rheumatoid arthritis" pptx
... galectin 3-binding protein, thuscontributing to the activated phenotype of RASFs. Theincreased activity of LINE-1 was associated with genomichypomethylation in RASFs. In accordance, very recent ... plays a central role in theinduction of genes involved in immunity and inflammation,including cytokines, chemokines, adhesion molecules,receptors, and inducible enzymes such as COX-2 and inducible ... density and infiltration of inflammatory cells is ahallmark of RA. Although the initiating events are elusive, it hasbeen shown that the interaction of RASFs with invadingmacrophages, lymphocytes,...
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Báo cáo y học: "Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy" ppsx
... In our study, CT of the sinuses was performedonly to investigate symptoms. Sinus aspergilloma may remainasymptomatic for several years, however, and may thereforebe underestimated.Sinus involvement ... often a maxillarysinus. Aspergilloma has been found in 3.7% of patients under-going surgery for chronic inflammatory sinusitis [12].Sinus aspergilloma is often asymptomatic and may thereforebe ... fungal sinusitis may spread intracranially and, on the other hand, indolent inva-sive aspergillosis may be well tolerated. Evaluating the risk of progression to invasive disease is crucial in patients...
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Báo cáo y học: "Rituximab treatment in rheumatoid arthritis: how does it work" pdf
... auto-antibodies (rheumatoid factor and anti-citrullinated proteinantibodies), which can be found already in the preclinicalphase of the disease; the presence of lymphocyte aggre-gates containing B cells, ... known that B cells havedifferent functions that may be relevant in the pathogenesis of RA, which include antigen presentation, stimulation of T cells,cytokine production and production of autoantibodies. ... are often surrounded by largenumbers of plasma cells, in the inflamed synovium; and experimental studies showing, for instance, the effects of immune complexes containing rheumatoid factor on...
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