Báo cáo y học: "Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled trial" ppt
Báo cáo y học: "Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled trial" ppt
... this article as: James et al.: Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled ... prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled trialAlicia M James1*, Cylie ... required.Thisstudyaimstocomparetwoclinicallyapplied treatment options for the management of posterior heel pain associated with the clinical diagnosis of calcaneal apophysitis. Method Study DesignThis is a factorial randomised controlled trial;...
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Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx
... migration selectively [20]. In that study a highly specific neutralizing antibody againstIL-8 was administered in several types of acuteinflammatory disease, including lipopolysaccharide/IL-1induced ... (pro)inflammatory mediators suchas cytokines and matrix metalloproteinases [3]. Increasedexpression of inflammatory chemokines has been found in many inflammatory disorders, including hepatic ... blockade in inhibiting chronic synovial inflammation, there are somepossible pitfalls that could hamper the clinical use of thisapproach. Of particular importance is the redundancy of the system,...
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báo cáo hóa học: "Bayesian aggregation versus majority vote in the characterization of non-specific arm pain based on quantitative needle electromyography" pot
... as (2). In order to apply the above equations, the mean andcovariance are calculated using all of the MUPTs avail-able for training separated by class. The per-class meanand covariance may ... affected individuals lacks any clear diagnosticcriteria. In fact, the Harrington c riteria [4] define non-specific forearm pain as a pain in the forearm that failsto meet the diagnostic criteria for ... likely to be the most infor-mative overall, and further exploration of these features in a non-parametric analysis is warranted.We intend therefore to proceed to an analysis of thesedata using...
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Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... using a formulabased on data from 187 primary PAH patients in the NationalInstitutes of Health Registry, and was compared with predicted survival. The study indicates that bosentansubstantially ... bosentansubstantially increases survival, with survival estimates at1 year and 2 years of 96% and 89% compared with ViewpointCold hands — strained heart? Advances in the management of Raynaud’s phenomenon and ... therapy for PAHincreases the importance of diagnosis and monitoring of thiscomplication. Furthermore, since many principles of PAHmanagement translate to the management of RP, this raises the...
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Báo cáo y học: "MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis" pps
... and in mMLN51, 5'-TAATACGACTCACTATAGGGTACTCGTAAGATGGCG-GACCGG-3' and 5'-TAATACGACTCA CTATAGGG-TACTCTGCCTCTCCCCAGTCAC-3'. The siRNA sequenceswere selected in size ranging ... AJ292072). The oligonucleotides used for the dsRNA synthesis were, in hMLN51, 5'-TAATACGACTCACTATAGGGTACTCGTAA-GATGGCGGACCGG-3' and 5'-TAATACGACTCACTAT-AGGGTCCGTCCCCACTTTGCCTC-3', ... patients had visible joint ero-sions by radiography of the hand, and all satisfied the diagnos-tic criteria of the American College of Rheumatology (formerly the American Rheumatism Association) for...
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Báo cáo y học: "Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity" pdf
... and thereby the cata-bolic potential of the culture [6]. Gelatinase activity at 7, 11,and 17 days after catabolic treatment was compared with gelatinase activity after 7 days of IGF treatment, ... situ car-tilage degradation are new and have not been widely available.Only assays for measuring collagen type II degradation havebeen available in enzyme-linked immunosorbent assay (ELISA)formats ... (ELISA)formats [6,20-22]. Although assays for measuring sulphatedglycosaminoglycans (S-GAGs) are available, these assays donot distinguish between synthesis and degradation of the pro-teoglycans...
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Báo cáo y học: "AIT test has no problem in the detection of anti-ribosomal P" ppsx
... was a form of HEp-2 cell that was transfected with cDNA encoding human Ro60. A human macrophage cell linecalled the IT-1 cell line was first introduced at the AmericanCollege of Rheumatology ... Korea.Currently, IT-1 is being used under the name of the autoimmune target (AIT) test and it participates in the qualitycontrol program run by the Korean Society of LaboratoryMedicine [3]. In 1999 and ... anti-ribosomal P (anti-Rib-P) in the pictures they revealed. In addition to the anti-Rib-P that Mahler and colleagues mentioned, limitations of the HEp-2 cell line in the detection of autoantibodies...
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Báo cáo y học: " AIT test has no problem in the detection of anti-ribosomal P – authors’ response" docx
... antibodies. By contrast, many laboratories rely onHEp-2 cell substrates that are widely available as FDA andCE approved diagnostic kits from a variety of manufacturers. In their study, Jearn and Kim identified ... perform remarkably better. In the context of contemporary diagnostic assays such asWB, ELISA or multiplexed addressable laser bead immuno-assays, therefore, the data presented by Jearn and ... identified sera with anti-Rib-Preactivity based on a double immunodiffusion (ID) assay, andthen used these sera to determine the positivity and stainingpatterns in the AIT test. This method raises...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... reg-ulatory enzyme in the pathway. Malonyl-CoA serves as the basic chain-elongating substrate for the formation of long-chain saturated fatty acids catalyzed by FAS.It should be noted that cytoplasmic ... acetyl-CoA car-boxylase; AMPK, 5¢ AMP kinase; CPT, carnitine palmitoyltransfer-ase; FAS, fatty acid synthase; MCD, malonyl-CoA decarboxylase;OAA, oxaloacetate; TCA, tricarboxylic acid.M. J. Wolfgang ... – the sole precursor of fatty acids. The initial and committed step of de novofatty acid synthesis is the carboxylation of acetyl-CoAto form malonyl-CoA, catalyzed by ACC – the key reg-ulatory...
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Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"
... 1). Alterna-tively, a partial (Figure 2) or normal cementation of the spacer into the femoral canal provides the advan-tage of rotational and axial stability [3]. A normal ce-mentation has the ... strongly vary. In case of patient incom-pliance or inability to put partial weight bearing on the operated extremity, the patient should be rather considered as a candidate for a resection arthroplasty ... available hip spacers containing a substantial stainless steel central core with experi-mental spacers containing Steinmann pins, intrame-dullary nails with two lag screws and Charnley prostheses,...
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