báo cáo khoa học: " Connectedness of healthcare professionals involved in the treatment of patients with Parkinson’s disease: a social networks study" pot

... of healthcare professionals involved in the treatment of patients with Parkinson’s disease: a social networks studyMichel Wensing1*, Martijn van der Eijk2, Jan Koetsenruijter1, Bastiaan ... each with other, or havingheard of. ’ Having professional contact was defined in the questionnaire as ‘ having had professional contactabout at least one patient with PD who you are treating(including ... partici-pant and another box to indicate whether this personwas involved in professional contacts so far. Knowingeach other was defined in the questionnaire as ‘knowing the face, having talked to each...

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... moreimportant in the brain because it has an extraordi-narily diverse population of cells. The role of malonyl-CoA and other intermediarymetabolites is an exciting area of research and poten-tially ... in various organ systems. Even in organismslacking a brain, such as Caenorhabditis elegans, the nervous system plays a key role in maintaining energybalance [1–4]. In more advanced, mammalian ... feeding behavior and body weight. ACC, acetyl-CoA car-boxylase; AMPK, 5¢ AMP kinase; CPT, carnitine palmitoyltransfer-ase; FAS, fatty acid synthase; MCD, malonyl-CoA decarboxylase;OAA, oxaloacetate;...

báo cáo khoa học: "R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature" ppt

... of anthracyclines in the management of patients with FL. We conducted a meta-analysis of relevantliterature comparing the two treatment arms for FL with response being the final endpoint. Patients and Methods: ... stage 1. To make the data accurate and comparable across all four studies,we reassigned patients into two broad stages: early stage(Ann-Arbor stages I and II) and late stage (Ann-Arborstages ... testing the efficacy of maintenance therapy by rituximab may provide impor-tant data in the field of the best induction in patients with follicular lymphoma. In summary, we conclude that treatment...

Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx

... the minimal transcrip-tionally active fragment and are required simulta-neously to maintain transcription. The PHF3 protein was recovered in initial analysesand also contains a TFS2M domain ... protein domain architectures thatshare a canonical bipartite nuclear localization signaland a PHD domain (Zn ﬁnger) at the N-terminalregion. The long isoform also contains transcription fac-tor ... KS, Carlone DL, Jacobsen BM, Flodin A &Skalnik DG (2000) Cloning of a mammalian transcrip-tional activator that binds unmethylated CpG motifsand shares a CXXC domain with DNA methyltransfer-ase,...

Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf

... Gokhale, R.S., Agarwalla, S., Santi, D.V. & Balaram, P. (1996)Covalent reinforcement of a fragile region in the dimeric enzymethymidylate synthase stabilizes the protein against chaotrope-induced ... subunit of the tetrameric d-crystallin shows a surface with several convexand concave areas as indicated by a , ÔbÕ and ÔcÕ, which participate in subunit association. Two neighboring subunits (A and ... secondary structural changesare minimal. The drastic increase of hydrophobic patchesstrongly suggests that there is a molten globule intermediate[26]. This may be the reason why an off-pathway inter-mediate...

Báo cáo khoa học: Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells pptx

... to the increased Sp1 binding to GC boxesand DNase II promoter activity. Other mechanisms, suchas interactions with other factors, may also be involved in increasing the DNA binding and transcriptional ... 95 kDa were detected. The intensity of the 105 kDa band was signiﬁcantlyincreased in the PMA treated cells than in the control cells,whereas that of the 95 kDa band was not changed(Fig. 5A) . ... binding protein-1 (SREBP-1;ATCC). The probe was then added and the mixture wasincubated for a further 30 min at room temperature andimmediately loaded onto a 5% nondenaturing polyacryl-amide...

báo cáo khoa học: " Cold- and light-induced changes in the transcriptome of wheat leading to phase transition from vegetative to reproductive growth" pot

... abundance of a) TaAGL33 and b) TaAGL42: a comparison of array data (normalised intensity) of the three varieties at 3, 5 and 9 weeks post-germinationFigure 6Bar diagrams of transcript abundance of a) ... orthologues, or are functionalequivalents, of Arabidopsis genes involved in the four path-Bar diagram of TaVRN1 transcript abundance: a) a comparison of array data of the three varieties at 3, 5 and 9 ... was also an increase in tran-script abundance in leaf tissue of the winter varieties, butfrom a lower initial level. The same pattern of increase wasseen in the controls.Intergrative pathwayIn...

Báo cáo khoa học: " Mechanical ventilation and lung infection in the genesis of air-space enlargement" pptx

... consolidation, 5 to 15 non-coincident aeratedfields observed at a magnification of ×4 were analyzed oneach histological section. Mean alveolar area was determinedas the average area of the aerated ... alveolar area was measured in aerated lung regions (left panel), and mean bronchiolar area was measured in aerated and non-aerated lung regions (right panel). Data are expressed as median and ... mechanically ventilated for a maximum of 60 hours orless if they died before. ZEEP was maintained and FiO2 (frac-tion of inspired oxygen) was increased in order to maintainarterial partial...

Báo cáo y học: "Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled trial" ppt

... removal of apophysis [29]. A recent literature review concluded that due to novalid or reliable data being available regarding calcanealapophysitis causation and no clinical trial comparing treatment ... such as calcaneal apophysitiscreates uncertainty for clinicians a ttempting to pursuean evidence-based treatment approach. These trials, andother similar trials, are needed to h elp clinicians ... completed with the Australian NewZealand Clinical Trial Registry ACTRN12609000696291.ConclusionPosterior heel pain associated with a clinical diagnosis of calcaneal apophysitis is a common...

Báo cáo y học: " Sustained favorable long-term outcome in the treatment of schizophrenia: a 3-year prospective observational study" ppsx

... approval was obtained ateach regional site prior to initiation of the study, and the study was conducted in accordance with the ethicalprinciples that have their originintheDeclarationofHelsinki ... amount of privacy where they live, the waythings are in general between them and their family, and the protection they haveagainst being robbed or attackedSatisfaction with social life SCAP-HQ ... active acquaintances, level of social activity, involved social network, social initiatives, social withdrawal, socio-sexual relations, extent of occupational role functioning, level of accomplishment,degree...

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