... and not lactose, is the natural substrate of the system. Thus, GGal taken up by the Mgl trans-porter will induce expression of the lac operon, and sopromote further uptake and utilization of ... kind of protein is exemplified by the Thermus thermophilus protein, PDB entry 2B3B [28]. The mode of binding the monosaccharide is completelydifferent in terms of orientation of the sugar, and ... observed, bound in the loops following the first helices of domains 1 and 2, respectively. The EF-hand-like calcium site of domain 2 was describedearlier, and tight binding of the ion was shown...