... Vatamaniuk OK, Bucher EA, Ward JT & Rea PA(2001) A new pathway for heavy metal detoxificationin animals. Phytochelatin synthase is required forcadmium tolerance in Caenorhabditis elegans. ... basic function, globally assumed to be related to metal homeostasis and ⁄ or metal-redox metabolism,may have been at the root of the appearance of MTs inliving organisms [6], and also one of ... 5¢-CGTGGATCCATGGCTTGCAAGTGT-3¢ (upstream) and 5¢-GCTCGAGTCGACTTACTCACAACACTTGTC-3¢ (downstream) andC-terminal fragment (residues 28–75), 5¢-CCGCGTGGATCCAAGTACTGCTGT-3¢ (upstream) and 5¢-CGACTCGAGTTAATGAGCCGCAGC-3¢...