báo cáo khoa học: "Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials" ppt
báo cáo khoa học: "Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials" ppt
... al.: Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials. Journal of Experimental ... 9RESEARCH Open AccessMagnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trialsFederica Cuppone1†, ... regard to the magnitude of the benefits and the overallsafety profile.Methods: A literature-based meta -analysis to quantify the magnitude of benefit and safety of adding bevacizumab to chemotherapy...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... One of the biggest challenges to the field is the lack of experimental tools to investigate intermediarymetabolites and lipids in general [54]. The application of ultrasensitive ... fatty acids. The initial and committed step of de novofatty acid synthesis is the carboxylation of acetyl-CoA to form malonyl-CoA, catalyzed by ACC – the key reg-ulatory enzyme in the pathway. ... leptin and ghrelin, as well as other hormones ⁄ cytokines,interact with their cognate receptors on neurons within the CNS that project to higher brain centers and to peripheral tissues to affect...
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Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc
... presenting the pulse of Src activity in the plane of the inactive and active fractions, si and s1. If the duration of the stimulus exceeds the critical value, the trajectory in the (si, ... transition from the Offstate to On state (in the bistability domain). Regardless of the slope, the active Src fractions increase during the Off to On transition, whereas the value of the inac-tive ... 2009 The Authors Journal compilation ª 2009 FEBSparameters and, for clarity of exposition, we present the analysis of the Src cycle in terms of Eqns (6–8).Intrinsic regulatory properties of the...
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Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx
... 4¢-phosphopantothenicacid, CTP and cysteine. The synthesis of PPC occurs in two half reactions starting with the formation of 4¢-phosphopantothenoyl-CMP (activation of the carboxyl group of 4¢-phosphopantothenate). ... synthetase. The proposed intermediate of the (R)-4¢-phospho-N-panto-thenoylcysteine synthetase reaction, 4¢-phosphopantothe-noyl-CMP, was characterized by MALDI-TOF MS and itwas shown that the ... synthesized in five steps fromD-pantothenate. The Dfp flavoprotein catalyzes the synthe-sis of the coenzyme A precursor 4¢-phosphopantetheinefrom 4¢-phosphopantothenate and cysteine using the...
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Báo cáo khoa học: A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A pot
... consists of 52 bp, similar to the case for mouse STAT5A. Therefore, we examinedwhether the splicing variant was expressed in the human brainstem. To minimize the amplification of STAT5B, the analysis ... STAT5A, similar to the case for the b-isoforms. It has been reported that the phosphorylated b-isoforms form heterodimers withfull-length STATs and decrease their activities [18].These heterodimers ... domain.STAT5A b-isoforms and STAT5B b-isoforms aregenerated by insertion of intron 18, and lack only the transactivation domain [18,20]. These STATb-isoforms are phosphorylated on the tyrosine residueafter...
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Báo cáo khoa học: Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris ppt
... (Table 2). These reveal the reversible activity of the transketolase and transaldolase reactions when P. pastorisis grown on glycerol. On the other hand, the wealth of information obtained for pathways ... molecule. The carbon skeletons of the intermediates of the glycolysis, TCA cycle and pentose phosphate pathway are represented by circles, squares and triangles, respectively. The numbering of the ... pastoris [34]. However, the 13C-labeling pattern arisingfrom the action of the glyoxylate cycle and the efflux of oxaloacetate (OAA) from the mitochondria cannot bedistinguished [18]. Hence, the...
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Báo cáo khoa học: Sodium pump a1 and a3 subunit isoforms mediate distinct responses to ouabain and are both essential for survival of human neuroblastoma docx
... different to that of the a1 isoform. The basis for these differentenvironments is may be due to differences in the struc-ture of the two proteins. The primary structures of the human a1 and a3 isoforms ... regions of the two proteins. These mightlead to specific targeting of each isoform to differentmicro-environments of the plasma membrane or to isoform-specific interactions with other proteins of the micro-environments. ... a1ora3 isoforms. The recentdemonstration that the a1 isoform is recruited to the plasma membrane via interaction of adaptor protein 1with Tyr255 of this isoform supports this hypothesis, and demonstrates...
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Báo cáo khoa học nông nghiệp " Selection and development sweet potato varieties with high root quality for food processing in Northern and Central of Vietnam " MS4 pot
... from the Center of Weather Forecast of Thanh Hoa are shown in Tables 4 and 5. - In the first stage of growth in October until November, the weather was relatively good for the sweet potato plant ... potato varieties were 25.65% of HT2 and 25.38% of VC01. The values were much higher than those of Hoang Long (21.29%) and the local (20.49%). On the other hand, in the same varieties, the dry ... Among the six locations, the S1 and S5 seemed most suitable for the new sweet potato varietes to grow. In the total yield of S1, VC 04-24, VC 02-193 and VC68-2 reached upto 33.27, 29.11 and 26.31...
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Báo cáo khoa học nông nghiệp " Achievements and lesson learnt from implementation of the project "Sustainable community-based forest development and management in some high-poverty areas in Bac Kan Province" " pot
... people on the rights to access to the community forest lands, the rights to harvest and the responsibility to protect the community forest is considered as the most important activity for the success ... socioeconomic and culture conditions - Capacity building for local people on the rights to access to the community forest lands, the rights to harvest and the responsibility to protect the community forest ... communities the confidence to contribute and invest labor and other inputs to the protection and development of community forest lands for overall local benefit; Lessons learnt: - The border of community...
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Báo cáo khoa học: "Prior surgical intervention and tumor size impact clinical outcome after precision radiotherapy for the treatment of optic nerve sheath meningiomas (ONSM)" docx
... SA, SR and SC collected the data. SC and SA evaluated the dataset and performed statistical analysis. SC, SA, SR, TW and JD wrote and edited the manuscript. All authors read and approved the manuscript.Conflict ... safety margin for the planning targetvolu me (PTV). The median PTV was 9.2 ml. Radiother-apy planning for FSRT was performed using the Voxel-plan®software developed at the German Cancer Research ... surgeryappear to present with more severe and irreversiblesymptoms, whereas patients in the radiation-only groupsuffer from symptoms caused by compression of the ONSM of normal tissue structures. In the...
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Từ khóa: Báo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ