báo cáo khoa học: " Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implications" ppsx

... Open Access Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implicationsHong-Feng Gou1†, Xin-Chuan Chen2†, Jiang Zhu1, Ming Jiang1, ... expression and VEGF-C expression or COX-2 and VEGF-C mRN A levels in several types o fcancer [57-59]. In our study, we did not find correla-tions between COX-2 and VEGF-C, or COX-2 and LVD. Though COX-2 ... expression of COX-2 and VEGF-C protein and the levels of lymphaticvessel density (LVD) in human gastric cancer and ana-lyze their correlations with clinicopathological character-istics and prognosis.MethodsPatients...

Báo cáo khoa hoc:"Expression of common fragile sites in two Ceboidea species: Saimiri boliviensis and Alouatta caraya (Primates: Platyrrhini)" pptx

... Slides with abnormal cells were destained and re-analyzed aftersequential G-banding [59] to identify the breakpoints involved in CA. The kary-otype of each species was considered following previously ... variability within and across populations of Cebusapella in Argentina, Folia Primatol. 54 (1990) 206–216.[42] Mudry de Pargament M., Slavutsky I., Banding patterns of the chromo-somes of Cebus ... regions [50]. Another c-fra, 11q15, coincides with aterminal deletion of a C-band in C. a. nigritus [44] and paracentric inversionsobserved in C. a. robustus and C. a. xanthosternos [37]. Three...

báo cáo khoa học: " Utility of EST-derived SSR in cultivated peanut (Arachis hypogaea L.) and Arachis wild species" potx

... occurred in A. cardenasii, one in A. duranensis, and two in A. pintoi.DiscussionFrequency and distribution of EST-SSRsThe frequency of SSRs in SSR-ESTs more accurately reflectsthe density of SSRs ... EST-SSR in every 7.3kb. In previous reports, an EST-SSR occurs every 13.8 kb in Arabidopsis thaliana, 3.4 kb in rice, 8.1 kb in maize, 7.4kb in soybean, 11.1 kb in tomato, 20.0 kb in cotton and 14.0 ... common motif found in both monocots [22] and dicots [23]. During the process of mining EST-SSRs in thePolyacrylamide gel electrophoresis patterns of microsatellite alleles amplified with the primer...

Báo cáo khoa học: "Comparison of P-wave dispersion in healthy dogs, dogs with chronic valvular disease and dogs with disturbances of supraventricular conduction" pptx

... an increase of the averagemaximum and minimum duration of P-wave, correlated with the increase of body weight, which goes together with the increased size of the heart, particularly the size of atrias. ... Pdvalue as an inde-pendent parameter for evaluating inter and intra-atrialconduction.There was noticed a significant increase in Pd in dogs with increased left atria due to insufficiency of the ... the group of dogs with insufficiency of mitral valve there were no correlations noticed with the increase of Pd and the level of left atria enlargement(p = 0.1, r = 0.17). In multiple linear regression...

Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"

... rapidly and thepropensity to err rapidly increases after 16 hours of sustainedwakefulness, a finding reflected in the twofold increase in interns’ attentional failures after they had been working ... performance of upper-levelresidents and other medical staff across a variety of disciplines. We likewise agree that optimizing patient hand-offs, medical education, and trainees’ sense of professionalism ... impact of hand-offs, which by definition occurred more frequently in the intervention schedule. Even with this special attention tohand-offs, at least one physician who attended the intensivecare...

Tài liệu Báo cáo khoa học: Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects doc

... min postinjec-tion), suggesting a high binding capacity of ETA in hepatic parenchyma. Indeed, injection of the toxin intomice has been shown to result in an early and pro-found inhibition of ... cathepsins B and D, with themajor cleavages generated in vitro occurring mainly within domain III of ETA-A. Cell-free endosomes preloaded in vivo with ETA intraluminallyprocessed and extraluminally ... loss of intact ETA and ETA-A in the presence of ATP, with concomitant generation of ETA and ETA-A fragments. Incubation in theabsence of ATP revealed a small amount of degrada-tion for intact...

Tài liệu Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development pptx

... section and scheme of the coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the ... of cHSF2,mHSF2 and rHSF2 are associated with nuclear locali-zation within the developing neural tube [3,62,121]. In addition, mHSF2 is associated with DNA binding in the developing brain, including ... HSF4-bindingregions and of the transcriptional status of geneslocated around the HSF4-binding regions. This resultis thus suggestive of a structural effect of HSF4 onchromatin. In the absence of...

Tài liệu Báo cáo khoa học: Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses pdf

... protein is2E4L. For the entire structure (A), N and C represent the N- and C-termini of the protein, and a and b represent the a helix and b strand,respectively. The side-chains of the mutated and ... proteins, because of the intrinsic ﬂexibility of theloop containing His124 and the crystal packing effect.Destabilization mechanism of So-RNase HIA combination of the six thermostabilizing ... structure of the 6·-RNase HI protein was deter-mined at 2.5 A˚resolution. The main chain fold and interactions of theside-chains of the 6·-RNase HI protein were basically identical to those of the...

Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt

... activity and the cytotoxic action of ExoS in vivo.Result and discussionAcidic residues within the 14-3-3 bindingdomain of ExoS are not strictly needed forphosphorylation-independent bindingThe interaction ... These infections were washed free from bacteria and transferred to new Petri dishes and incubated with medium contain-ing penicillin, streptomycin and gentamicin to ascertain the reversibility of ... activity in vivo. We have approached these questions using astrategy of single amino acid site-directed mutagenesis of the cofactor interaction domain within ExoS.Various single mutant ExoS proteins...

Tài liệu Báo cáo khoa học: Characterization of electrogenic bromosulfophthalein transport in carnation petal microsomes and its inhibition by antibodies against bilitranslocase docx

... sulfo-bromophthalein to rat and human ligandins: characteri-zation of a binding-site peptide. Biochim Biophys Acta955, 296–300.52 Gregus Z & Klaassen CD (1982) Role of ligandin as abinding protein and ... anthocyanin sequestration, is a ﬂavonoid-binding protein. Plant Physiol 123, 1561–1570.24 Grotewold E (2004) The challenges of moving chemicalswithin and out of cells: insights into the transport of plant ... A of the table; Ki of cyanidin 3-glucoside, section B), or described in detail in both the experimental procedures(Ki of cyanidin, bilirubin, biliverdin, section B) and in Table 2 (Kdof...

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