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Báo cáo y học: "Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice" pot

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Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"

... supported by the recent findings of McCarty et al, who showed an effect of anagrelide on CD41 numbers and TPO-specific pTyr activity in vitro, indicating that anagrelide reduces the TPO-mediated intracellular ... Lacey D, Hill D, Chen Y, Fletcher F, Hawley RG, McNiece IK A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone ... Giraudier S, Vainchenker W, Wendling F. Prominent role of TGF-beta 1 in thrombopoi-etin-induced myelofibrosis in mice. Blood 2002;100:3495-503 32. Erusalimsky JD, Franklin R and Hong Y. Is the...
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Báo cáo y học: "Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence" pps

... enzymes, decreasing the activities of arylsulfatase A and arysulfatase B, an N-acetyl-galactosaminidase-4-sulfatase, but increasing the activity of acid phosphatase in normal and OA chondrocytes ... further research is needed to evalu-ate the safety and potential benefits of cetyl myristoleate and cetylated fatty acids in the treatment of OA.Vitamins and mineralsDue to their antioxidant ... by chondrocytes [104].Uncaria tomentosa and Uncaria guianensis (cat's claw)Cat's claw is a vine from the basin of the Amazon River. Thereare two species, U. tomentosa and U. guianensis,...
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Báo cáo y học: "Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects" pot

... for citation purposes)Vol 9 No 2Research articleVaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, ... tet-anus toxoid and 23-valent pneumococcal vaccines. Serum samples were obtained for subjects of Groups A and B at study days 14 and 28, for Group C subjects at study days28 and 42, and for Group ... on antibody titers at 14 and 28 days after vaccination in individual pneumococcal serotypesImpact of abatacept on antibody titers at 14 and 28 days after vaccination in individual pneumococcal...
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Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx

... amyloid and advanced glycation end products (AGEs)[15]. AGEs are the products of nonenzymatic glycation and oxidation of proteins that form with aging, diabetes and renalfailure, and at sites of inflammation ... Goodson and colleaguesrecently demonstrated 10% mortality, predominantly owing toCV events, within 10 years of onset of inflammatory polyarthri-tis [27]. In a large study of CV mortality in RA ... and RAGEGly82→Ser polymorphism in 232 patients with RA attending atertiary referral hospital. CV events, the duration and severity of RA, and risk factors for CV disease were determined usingpatient...
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Báo cáo y học: "Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs" pdf

... or induce these inflammatory mediators.Accordingly, the present study examines the interplaybetween mechano-sensitive and cytokine-sensitive pathways, and determines the effects of IL-1β and ... or dynamic compression. In addition to the regulationof iNOS and COX-2 expression by dynamic compression, co-stimulation with the inhibitor was important in restoring thecytokine -induced inhibition ... compression inhibits IL-1β induced iNOS expression and production of nitrite releaseDynamic compression inhibits IL-1β induced iNOS expression and production of nitrite release. Effects of 15% dynamic...
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Báo cáo y học: "Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins" pdf

... 12:R65http://genomebiology.com/2011/12/7/R65Page 3 of 17 RESEARC H Open AccessProteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteinsJohan Nilsson1, ... (39 genes), again sug-gesting a positive correlation between intrinsic disorderand degree of positive selection within proteins. Intrinsically disordered regions are not depleted in functional ... for protein regions within known protein domains (PDB dom) or predicted intrinsically disordered protein regions of at least 30 residues in length (IDR ≥30). Thefrequency of positively selected...
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Báo cáo y học:

Báo cáo y học: "Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice" pot

... purposes)Journal of Circadian Rhythms Open Access Review Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient ... published by the samelaboratory, appear to establish the DMH as the site of a Bmal1- dependent circadian mechanismnecessary and sufficient for food anticipatory rhythms. However, careful examination ... and location of food- entrainable circadian oscillators hypothesized to control food anticipatory rhythms are unknown. In 2008, Fuller et al reported that food- entrainable circadian rhythms are...
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Báo cáo y học: "Standards of evidence in chronobiology: A response" docx

... remain awake and active, engaging in wheel-running and increased drinking of further MA, andfurther wheelrunning, until the animals are exhausted andsleep (at which point they stop drinking MA ... the last paragraph of our paper is: " ;In an intact animal, peripheral oscillators in many tissues in the body, including the stomach and theliver, as well as elsewhere in the brain, may contribute ... food-anticipatory circadian rhythm following dor-somedial hypothalamic ablation in rats. Am J Physiol Regul IntegrComp Physiol 2006, 290:R1527-R1534.6. Moriya T, Aida R, Kudo T, Akiyama M, Doi M, Hayasaka...
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Báo cáo y học: "If you don''''t believe it, it won''''t help you": use of bush medicine in treating cancer among Aboriginal people in Western Australia" pps

... original work is properly cited.Research"If you don't believe it, it won't help you& quot;: use of bush medicine in treating cancer among Aboriginal people in Western AustraliaShaouli ... "Secrecy and mystery abound in the Aboriginal commu-nity about the use and availability of bush medicine. Thisinevitably means poor availability of accurate informationregarding its actual use. ... gonna help you, it will (emphasizing). It may not cure you. It may not save your life, but it will help you, even if it& apos;s only in a men-tal or an emotional way of help. So, I really do believe...
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Báo cáo y học: " Standards of lithium monitoring in mental health trusts in the UK" pot

... management of bipolar disorder. In 2009, 38 mental health Trusts in the UK participated in a baseline audit of the quality of lithium monitoring aspart of a quality improvement program (QIP) run by the Prescribing ... contributed to the methodology of the study, interpretation of the data and drafting the paper. CP: contributed to the literature search, the design of the study, analysis and interpretation of the data, ... in the acceptance of the need for monitoring at the frequency recommended by NICE. The use of incentivised care in improving monitoring practice Mental health Trusts within the UK are required...
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Báo cáo y học: " Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical data" doc

... al.: Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical ... 7:328http://www.virologyj.com/content/7/1/328Page 3 of 8 RESEARC H Open Access Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage ... measurement of HSV DNA in cervicovaginal lavage (CVL) specimens of women with mostly longstanding HSV-2 infection within the setting of a research cohort with semiannual scheduling of fol-low up and...
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Báo cáo y học: " First serological evidence of West Nile virus in human rural populations of Gabon" pdf

... al., First serological evidence of West Nile virus in human rural populations of Gabon Virology Journal 2010, 7:132 Pourrut et al. Virology Journal 2010, 7:132http://www.virologyj.com/content/7/1/132Open ... transmission patterns in Gabon.Findings West Nile virus (WNV) is a mosquito-borne RNA virus belonging to the genus Flavivirus, family Flaviviridae.Although human WNV infection is generally asymptom-atic ... virus in human rural populations of GabonXavier Pourrut*1,2, Dieudonné Nkoghé2, Janusz Paweska3 and Eric Leroy1,2AbstractTo investigate West Nile virus (WNV) circulation in rural populations...
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Báo cáo y học: " Multi-symptom asthma is closely related to nasal blockage, rhinorrhea and symptoms of chronic rhinosinusitis-evidence from the West Sweden Asthma Study" doc

... between multi-symptom asthma and different symptoms of allergic and chronic rhinosinusitis.Methods: This study analyzed data on asthma symptoms, rhinitis, and chronic rhinosinusitis from the 2008 West Sweden ... bacteria and fungi, could interfere with both nasal symptoms and the severity of asthma [13].In addition to the number of nasal symptoms, severalother factors appear to distinguish the multi-symptom and ... previously.Theaimofthecurrentstudywastodeterminewhether multi-symptom asthma is related to signs of severe asthma, and to describe the association betweenmulti-symp tom asthma and different symptoms of nasal disease...
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Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" ppsx

... purposes)Poly(I:C) induces a dose dependent influx of inflammatory cells into the airways of miceFigure 1Poly(I:C) induces a dose dependent influx of inflammatory cells into the airways of mice. ... comparisons.ResultsPoly(I:C) induces a marked inflammatory response in the lungs of miceIntranasal administration of three once-daily doses of poly(I:C) resulted in a dose-dependent inflammatory cellinflux into the lung. ... pro-inflammatory cytokines in the lungs following viral infection representsa crucial step in promoting the inflammatory response in various lung diseases [7,8]. A better understanding of theeffects...
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Báo cáo y học: " No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms" doc

... for citation purposes)RetrovirologyOpen AccessResearch No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasmsThomas Burmeister*1, ... T-cell (50) Early T-cell lymphoblastic 11Cortical (thymic) T-cell lymphoblastic31 34 (17–63) Mature T-cell lymphoblastic 8 Mature T-cell (31) T-prolymphocytic 16Sézary syndrome and Mycosis fungoides5Ki-1 ... draw-gram was used with the default parameters to construct aphylogenetic tree from the aligned sequences.ImmunophenotypingImmunophenotyping by FACS analysis was done essen-tially by standard methods...
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