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Báo cáo y học: "Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice" pps

Báo cáo y học:

Báo cáo y học: "Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice" pps

... number not for citation purposes)Journal of Circadian RhythmsOpen AccessShort paperWildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in ... HomozygousEgfrwa2 mutant and wildtype littermates were evaluated for defects in locomotor and masking behaviors.Results: Mice homozygous for Egfrwa2 showed normal daily locomotor activity ... implicated the epidermal growth factor receptor (EGFR) withinthe subparaventricular zone as being a major mediator of locomotor and masking behaviors in mice. The results were based on small cohorts of...
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Báo cáo khoa học: " The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications" pptx

... intracellular tyrosine kinasedomain.Binding to EGFR by its natural ligands, mainly EGF or transforming growth factor alpha (TGF-α) results in a con-formational change in the receptor, which promoteshomodimerization ... signal-regulated kinases: associationwith epidermal growth factor receptor/ transforming growth factor alpha expression in head and neck squamous carci-noma and inhibition by anti -epidermal growth factor recep-tor ... Radiation-induced release of transforming growth factor α activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased...
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Báo cáo y học: "Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity" ppsx

... positive for the common-Smad,Figure 2Staining of various transforming growth factor (TGF)-beta signaling molecules in cartilageStaining of various transforming growth factor (TGF)-beta signaling ... PG synthesis or whole knee joints were isolated for histology to measure PGcontent in the cartilage.Histology For the different classes of Smads, knee joints were decalci-fied for 14 days in ... osteophyte formation and synovial thickening byadenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experi-mental osteoarthritis. Arthritis...
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Báo cáo y học: "Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women" ppt

... 1,25(OH)2D binds to nuclear vitamin Dreceptors in tissues throughout the body. Active vitamin D is responsible for maintaining calcium homeostasis pri-marily by increasing the efficiency of intestinal ... example, in two seminal papers, Liu et al demonstrated that poor vita-min D status may increase susceptibility to Mycobacteriumtuberculosis infection by inefficiently supporting the induc-tion ... scheduled for testing. Subjectswere instructed to refrain from exercise and to fast (wateronly) for 8 to 10 hours prior to their scheduled morningvisit. On testing day, all subjects of childbearing...
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Báo cáo y học: "Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy" pps

... proteins and MHC–HC gp39 complexes) [3,4].Although certainly not excluding a secondary effector func-tion for lymphocytes in SpA or for macrophages in RA syn-ovitis, these findings point towards ... spondyloar-thropathy (SpA) (lining-layer hyperplasia, inflammatory infiltration, polymorphonuclear cells, sublining CD68, and sublining CD163)Supervised clustering analysis using the synovial histopathological ... significantly associated with disease activity in spondyloar-thropathy (SpA) (lining-layer hyperplasia, inflammatory infiltration, polymorphonuclear cells, sublining CD68, and sublining CD163)....
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Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx

... regression model. This finding is in line with a previous study on major infections in SLE patients in the Hopkins Lupus Cohort [32].Renal insufficiency is a possible risk factor for infections. How-ever, ... opsonise pathogens and enhance the activ-ity of phagocytes [12].Homozygosity for variant MBL alleles is probably a minor risk factor for the presence of SLE, as shown by a recent meta-analysis ... D, Steiner G: Riskfactors for coronary heart disease in women with systemiclupus erythematosus: the Toronto Risk Factor Study. ArthritisRheum 2003, 48:3159-3167.34. Selzer F, Sutton-Tyrrell...
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Báo cáo y học: "Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link" docx

... acid is an independent predictor of all-causemortality in patients at high risk of cardiovascular disease: apreventive cardiology information system (PreCIS) databasecohort study. Arthritis ... S, Yipintsoi T: Riskfactors for development of decreased kidney function in asoutheast Asian population: a 12-year cohort study. J Am SocNephrol 2005, 16:791-799.44. Iseki K, Ikemiya Y, Inoue ... T, Iseki C, Kinjo K, Takishita S: Signifi-cance of hyperuricemia as a risk factor for developing ESRD in a screened cohort. Am J Kidney Dis 2004, 44:642-650.45. Iseki K, Oshiro S, Tozawa M, Iseki...
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Báo cáo y học: " RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models" ppt

... RT-SHIV from infected cellsreadily infects CEMx174 cells and induces marked syncy-tia in the culture. Infection was monitored by microscopicexamination for syncytium formation and by measuringSIV ... number not for citation purposes)also in many different human CD4+T cell lines. This viruspreferentially utilizes the CCR5 coreceptor for entry intothe target cells. The in vitro efficacy and ... characteristics of ahighly infectious and rapid replicating CCR5-tropic virus.Coreceptor usage of RT-SHIV for the entry of target cellsThe chemokine receptors CCR5 and CXCR4 are the twomain coreceptors...
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Báo cáo y học: "From novice to expert: agroecological competences of children orphaned by AIDS compared to non-orphans in Benin." pps

... each category, that is for form and functionseparately [49,56]. The quality of expertise is obtainedby weighting group mean for form and function respec-tively, by the sum of means for form and ... anticipated.The differences in expertise for the use of form andfunction descriptors between orphans and non-orphanswere further investigated by disaggregating the cate goryof orphans (Table 5). A ... use form and func-tion descriptors. In t his regard, an index of expertise(IE) was calculated by checking the number of mentionswithin a group of informants by the total number ofitems in...
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Báo cáo y học: "Computerized tomography myelography with coronal and oblique coronal view for diagnosis of nerve root avulsion in brachial plexus injury" potx

... was not routinelyperformed, since the nerve graft is not effective in thelower roots. Brachial plexus exploration cannot revealintraforaminal rootlet lesions unless laminectomy is per-formed. ... articleComputerized tomography myelography with coronal and oblique coronal view for diagnosis of nerve root avulsion in brachial plexus injuryHiroshi Yamazaki*1, Kazuteru Doi2, Yasunori Hattori2 and ... reliability wasassessed.The image findings were compared with the diagnosis for 57 cervical roots in 28 patients. Diagnosis was based onintraoperative findings in 25 patients and clinical findingsof...
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