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Báo cáo y học: "Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal" pps

Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

... compilation ª 2010 FEBS 4851 Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Yã) ... Auling G (1998) Clon-ing and sequencing of the nrdF gene of Corynebacterium ammoniagenes ATCC 6872 encoding the functionalmetallo-cofactor of the manganese -ribonucleotide reductase (Mn-RRase). ... chemistry involv-ing an array of diverse metallocofactors. The nucleotide reduction gene (nrdF) encoding the metallocofactor containing small subunit (R2F) of the Corynebacterium ammoniagenes ribonucleotide...
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

... iron- loaded HepG2 cellsFEBS Journal 272 (2005) 152165 ê 2004 FEBS 163 Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading Marisa Cabrita1,*, ... intra-cellular lipids regulate expression of CD1d at the cell surface, we examinedparameters of lipid metabolism in iron- loaded HepG2 cells. Interestingly,increased expression of CD1d molecules by iron- loaded ... background staining (thin lines). Cells were then acquired in a FACScali-bur and analyzed usingCELLQUEST. (A) Histograms show the expression of the molecules studied in HepG2 cells cultured in the absence(–...
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Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt

Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt

... G. Berrin et al. (Eur. J. Biochem. 269) Ó FEBS 2002 Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides Jean-Guy ... itmight have a role in human aging [6].Finally, a b-glucosidase, termed cytosolic b-glucosidase, is present in the liver, kidney, intestine and spleen of humans. This c ytosolic b-glucosidase ... human liver. Furthermore, we investigated the speciđcity of the human CBG with r espect to the glyconeand aglycone moieties, and in particular characterized the efđciency of the enzyme in hydrolysing...
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Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc

Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc

... Glutathione reductase in male reproduction system (Eur. J. Biochem. 269) 1571 The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione ... cysteine, andglycine, via two ATP-con suming s teps involving c-g lut-amylcysteine synthetase ( cGCS) and glutathione synthetase. The other constitutes a recycling system involving GRwhich reduces ... meas-uring its enzymatic activity and examining the gene expression and localization of the protein. Levels of GRactivity, the protein, and the corresponding mRNA were the highest in epididymis...
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Báo cáo Y học: Balanced expression of single subunits in a multisubunit protein, achieved by cell fusion of individual transfectants docx

Báo cáo Y học: Balanced expression of single subunits in a multisubunit protein, achieved by cell fusion of individual transfectants docx

... protein, achieved by cell fusion of individual transfectants Lars Norderhaug1, Finn-Eirik Johansen2and Inger Sandlie31Antibody Design AS, Nesoddtangen, Norway;2Department of Pathology, Rikshospitalet, ... forproduction of total SC, by a dot blot approach. Triplets of Fig. 1. A schematic diagram of the fusion of cells producing individual protein units of a multisubunit protein. Three transfected CHO-K1 cell lines ... IgG) Ig(DAKO; 1 : 3000 dilution). The absorbance was read by TitertekÒ Multiskan (ICN Flow, USA). The amount of IgA present in each supernatant was calculated relative to a standard preparation...
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Báo cáo y học: "Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study" pps

... changes in HAAP include marked proliferation of synoviocytes in thesynovial lining layer, gross infiltration of lymphocytes, andmigration of atypical lymphocytes with nuclear indentationinto the ... K, Kitajima I, Nishioka K, Yamamoto K, Takeda T, Hatanaka M, Yamamoto H,Sekiguchi T: Induction of inflammatory arthropathy resemblingrheumatoid arthritis in mice transgenic for HTLV -I. Science1991, ... patchy staining involving several areas; ++, moderate diffuse staining. OST, osteotomy; SYV, synovectomy; TA, total joint arthroplasty. Available online http://arthritis-research.com/content/6/4/R347R349Inc.)....
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Báo cáo y học: "Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus" ppsx

... 1 Expression < /b> of < /b> chemokine < /b> receptors < /b> in peripheral < /b> blood < /b> B cells from a healthy donorExpression of < /b> chemokine < /b> receptors < /b> in peripheral < /b> blood < /b> B cells from a healthy donor. Flow cytometric plots show chemokine < /b> ... CXCR3hi expression < /b> on < /b> B cell subpopulationsChemokine receptor CXCR3hi expression < /b> on < /b> B cell subpopulations. The percentage of < /b> total B cells, naive B cells, memory B cells and plasma cells expressing ... migration of < /b> B Figure 5 Chemokine < /b> receptor CCR6+ expression < /b> on < /b> B cell subpopulationsChemokine receptor CCR6+ expression < /b> on < /b> B cell subpopulations. The percentage of < /b> total B cells, naive B cells, ...
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Báo cáo y học: "Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues" doc

... original work is properly cited.Abstract The focal adhesion kinase (FAK) family kinases, including FAK and proline-rich kinase 2 (Pyk)2, are the predominant mediators of integrin αvβ3 signaling ... kinase (FAK) and proline-rich tyrosine kinase (Pyk)2 are two members of a family of nonreceptor protein tyrosine kinases that are acti-vated by a variety of extracellular stimuli [1]. FAK and ... with FAK, including paxillin [38]. Overexpression of FAK and PLCγ in COS-7 cells increases PLCγ enzymatic activity and tyrosinephosphorylation. FAK- induced PLCγ phosphorylation may bedue to FAK...
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Báo cáo y học: "Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites" potx

... reproduction in any medium, provided the original work is properly cited. Plasmodium duplicate gene expression<p> ;Duplicated var2csa genes in one strain of Plasmodium falciparum are simultaneously ... between highly similar gene copies in P. falciparum parasites.The duplicated var2csa variants are simultaneously transcribed, both on a population level andintriguingly also in individual cells, ... transcribed in individual parasites collected at24 ± 4 h post-invasion (p.i.; Figure 5a). Transcription of bothallele types was readily detected in the majority of cells ana-lyzed, independent of the...
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Báo cáo y học: "Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal" pps

... 1 of 9(page number not for citation purposes)Journal of Circadian RhythmsOpen AccessResearchAltered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence ... mPER1 protein expressed in the brains and kidneys of Con, MD and MW miceFigure 4 Circadian variation of mPER1 protein expressed in the brains and kidneys of Con, MD and MW mice. The inte-gral ... protein expression in brains and kidneys. a: Positive staining in the nucleus and cytoplasm are found in brains of Con, MD and MW mice. b: Representative cases show positive staining for mPER1 in...
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Báo cáo y học: "Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawa" docx

... limitation of video recording duringdarkness by using a camera that, by automatically switch-ing to infrared in complete darkness, allowed us to contin-uously monitor activity during the light and ... the amount of overallActivity of a rat in L:D and D:D conditionsFigure 6Activity of a rat in L:D and D:D conditions. Top: 3rd day in LD conditions ; bottom: 5th day under free-running, DD con-ditions ... locomotor activity is a valuable tool foranalysing factors influencing behaviour and for investigat-ing brain function. As a result, assessment of locomotoractivity has been used in many fields such...
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Báo cáo y học: "Altered expression of T cell Immunoglobulin-Mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis" docx

... suggestingthat TIM-1 controls critical regulatory pathways in theimmune system. Studies on mice have indicated that TIM-1 is involved in T helper cell differentiation and suggestedthat the protein ... represent a T cell defect to control the Th1 response, which might contrib-ute to the accumulation of inflammatory cells in the lungsand the pathogenesis of sarcoidosis.Competing interestsThe authors ... response in the lungs of patients with Löfgren's syndrome and those without. The triggering event is the presentation of an (unknown) antigen by antigen-presenting cells (APC) to T cells. In the...
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Báo cáo y học: "Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis" doc

... accompanied by the differentiation of normal lung fibroblasts into myofibroblasts. These myofibrob-lasts express α-smooth muscle actin, and they are thought to be the major source of collagen and profibrogenicgrowth ... Alterations in the susceptibility of these cells to Fas -induced cell death contribute to the pathogenesis of lung fibrosis, [6,7] and myofibroblasts are susceptible to the suppression of apoptosis by transforming ... sur-face bound FasL with surface Fas may initiate apoptosis.Consequently, the intensity and the stochiometry of the Fas -FasL interaction could play a crucial role in the regula-tion of apoptosis.In...
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Báo cáo y học: "Cost-effectiveness of three malaria treatment strategies in rural Tigray, Ethiopia where both Plasmodium falciparum and Plasmodium vivax co-dominate" ppsx

... al.: Cost-effectiveness of three malaria treatment strategies in rural Tigray, Ethiopia where both Plasmodium falciparum and Plasmodium vivax co-dominate. Cost Effectiveness and Resource Allocation ... savingis greater by avoiding over prescription. Over -treatment of malaria results in considerable morbidity and mortal-ity by delaying the correct treatment of non -malaria ill-ness and by contributing ... adequate training and continuous supervision of HEWs should also be main-tained. Finally, a study that captures the final health out-come of malaria dia gnosis and treatment strategies and assesses...
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Báo cáo y học: "Hepatic expression of multidrug resistance protein 2 in biliary atresia" ppsx

... gene expression of transporte rs [23 ,24 ]. MRP2 expression isdownregulated drastically in cytokinemia induced byendotoxin administration [25 -27 ]. In addition, MRP2 expression level in the BA liver was reported ... Revisited.Hepatology 20 02, 36: 525 -531.doi:10.1186/1476-5 926 -10-6Cite this article as: Terui et al.: Hepatic expression of multidrug resistance protein 2 in biliary atresia. Comparative Hepatology 20 11 10:6.Submit ... sclerosing cholangitis.Liver 20 01, 21 :24 7 -25 3.16. Yamada T, Arai T, Nagino M, Oda K, Shoda J, Suzuki H, Sugiyama Y, Nimura Y: Impaired expression of hepatic multidrug resistance protein 2 is...
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