...
Abstract
Background: Daylight saving time is widely adopted. Little is known about its influence on the
daily rest-activity cycles. We decided to explore the effects of transition into daylight saving time
on the ... the
drafting of the manuscript.
JL participated in the planning of the study and in the
drafting of the manuscript.
TP participated in...
... pathways from the synthesis of 3-ketoacyl
CoAs by a condensing enzyme to the incorporation of fatty
acids into lipids such as triacylglycerol or membrane
phospholipids. This in vivo system is therefore ... we also noted the level of activity found in
many of the chimeric enzymes. Many of the changes we
made resulted in chimeric enzymes with substantially
lower activity t...
... other b subunits shown in ou r yeast two-
hybrid system experiments, it is reasonable to suppose a
possibility of a replacement of one b subunit by another i n
the case of a deficiency of any of ... phosphorylation activity of the CK2 a subunit
[39]. The functional homology of the Stellate protein with
the CK2 b subunit rises the f ormal possibility t hat the
Stella...
... respectively). The three phases of the
potential-dependent development of the difference signals
can be attributed to the cooperativity between the hemes a,
a
3
and the Cu
B
center, showing typical ... the sample with cyanide allows assigning the
formyl signals upon characteristic shifts of the m(C¼O)
modes, which reflect the high degree of similarity of heme a
3
t...
... with PsA (but their results were not analyzed
separately). They confirmed that MRI sacroiliitis was very
common in SpA, most often involving the dorsocaudal part of
the joint in early disease in ... used manual
outlining of synovial membrane to quantify synovitis in their
study of 84 patients with inflammatory arthritis, 18 of whom
had reactive arthritis or PsA. MRI of the wri...
... to
study the therapeutic effects of systemic infliximab therapy on
the synovial expression of other important pro-inflammatory
molecules [38,47]. Infliximab treatment in another small cohort
of patients ... RA saw the number of TNF-synthesising cells
readily reduced and the production of IL-1α and IL-1β incon-
sistently down-regulated[47]. IL-15 was not inhibited by anti-
TN...
... permission.
The epidemiology of systemic lupus
erythematosus
A population-based study examined the incidence and
mortality of systemic lupus erythematosus (SLE) in a
geographically defined population ... history of JRA have been shown to
have a lower life expectancy than members of the general
population of the same age and sex. Over 25 years of follow
up of a cohort of...
... stance
(partly, I’m sure, in relief that they didn’t get the axe
them selves) are still going to be on your side in the
future? I’m reminded of the fable by Aesop of the
Travelers and the Bear: ... of course, you don’t.
en there’s the question of whether the state legis-
lature’s inaction gave you no other choice. I’m sure the
budgetary problems you have to deal...
... whether the
spectral sensitivity of the circadian system also changes throughout the solar day. Reported here is
a new study that was designed to determine whether the spectral sensitivity of the ... spectral sensitivity of
circadian phototransduction mechanisms at two different times of the night. These findings are
hypothesized to be the result of a change in the s...
... and
allows the estimation of DSM-IV diagnoses for major dis-
orders [21]. The translation of the M-CIDI into Finnish
was made pair wise by psychiatric professionals and
revised by others. The official ... successfully genotyped, yielding the suc-
cess rate of 100% for all SNPs, and about 5% of samples
were re-genotyped to confirm the genotyping results. The
following t...