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Báo cáo y học: "Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection" ppt

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Báo cáo y học: "Anti-tumorigenic and Pro-apoptotic effects of CKBM on gastric cancer growth in n" potx

... study demonstrates the anti-tumorigenic action of CKBM on gastric cancer probably via inhibition of cell proliferation and induction of apoptosis, and provides future potential targets of this ... Panax ginseng: a role in cancer therapy? Integr Cancer Ther. 2003, 2:13-33. 4. Shin JY, Song JY, Yun YS, Yang HO, Rhee DK, Pyo S. Immunostimulating effects of acidic polysaccharides extract of ... transduction pathway in carcinogenesis of gastric cancer. Wallace Hau-Leung So (B.Sc.) is technician in Department of Pharmacology, University of Hong Kong. He is actively involved in various areas of...
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Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx

... appear to play key roles in the pathogenesis of RA, and the co-ordinated production of chemokines andproinflammatory cytokines is probably important in the orchestration of the inflammatory responses ... al.Research article A novel mechanism for the regulation of IFN-γγ inducible protein-10 expression in rheumatoid arthritisRyosuke Hanaoka1, Tsuyoshi Kasama1, Mizuho Muramatsu1, Nobuyuki Yajima1, ... ultraviolet transillumination.Statistical analysisData were analyzed on a Power Macintosh computer using a statistical software package (Statview 4.5; AbacusConcept Inc, Berkeley, CA, USA) and expressed...
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Báo cáo y học: "Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener’s granulomatosis" pptx

... epiphenomenon[10]. One of the unresolved issues is the inability toexplain the nonrandom, selected organ injury that defines the WG vasculitis and the concurrent, seemingly random,nature of injury within ‘targeted’ ... the PR-3 expression in normal lung and lung tissue of WG patients, as the lung is the most frequent organ involved in WG [15]. In normal lung tissue, mainly pneumocytes type Iand type II and just ... kidney, nose and lung) . Little is knownabout the expression and distribution of PR-3 in the lung. We found that PR-3 is expressed in normal lung tissue and is upregulated in lung tissue of patients...
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Báo cáo y học: "No evidence for an association between the -871 T/C promoter polymorphism in the B-cell-activating factor gene and primary Sjögren''''s syndrome" pptx

... compared by χ2 test-ing. The association between BAFF polymorphism and BAFFprotein or mRNA level was analyzed using the Mann–WhitneyU test. The association between BAFF polymorphism and serum ... performed using trans-fectant expressing -871 T in the promoter gene. Likewise, the functional difference between -871 T and -871 C on transcrip-tion factor binding should be investigated using ... allele and increased BAFF mRNA level in blood mono-cytes. We therefore investigated the association between BAFF -871 T/C polymorphism and BAFF expression, and focused first on the correlation between...
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Báo cáo y học: "Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes" pps

... one of which is N-acetylation; the result-ing N-acetylglucosamine can modify several proteins by cou-pling itself to the serine or threonine residues of thoseproteins. These include kinases, ... subunit, namely p65 (data not shown).The decreased phosphorylation MAPKs may be explained bythe role played by glucosamine in O-glycosylation of someproteins. Glucosamine, when it enters into the ... S, Ouzzine M: Interleukin-1beta down-regu-lates the expression of glucuronosyltransferase I, a keyenzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated...
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Báo cáo y học: "Cerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 infectio" docx

... sclerosis [5,10].CSF NFL increased substantially in three of our eight sub-jects studied after stopping antiretroviral therapy, therebyindicating brain injury in this setting. The mechanismsresponsible ... CentralPage 1 of 7(page number not for citation purposes)AIDS Research and TherapyOpen AccessResearchCerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 ... unexam-ined potential concern when interrupting antiretroviral treatment – the possibility of nervous system injury –although further studies are needed to confirm the fre-quency of this finding...
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Báo cáo y học:

Báo cáo y học: "Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection" ppt

... performed in Inns-bruck (Gothenburg, Milan, Sydney and some of SanFrancisco samples) and San Francisco (majority of SanFrancisco samples including all HIV negative samples);while formal quality control ... such as cyclosporin-A, andTh2-type cytokines including interleukin-4 and -10 coun-teract the production of neopterin [21]. The same is truefor anti-inflammatory compounds including certainHMG-CoA ... HIV-Figure 1 Induction of neopterin formation in brain cells. Pro -in- flammatory cytokines like interferon-γ (IFN-γ) induce expression of GTP-cyclohydrolase I in various brain cells. As an intermediate...
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Báo cáo y học: "Possible gabapentin and ketamine interaction causing prolonged central nervous system depression during post-operative recovery following cervical laminoplasty: a case report" potx

... Possible gabapentin and ketamine interaction causing prolonged central nervous system depression during post-operative recovery following cervical laminoplasty: a case report. Journal of Medical Case ... recovery following cervical laminoplasty: a case reportAli R Elyassi*, Robert P Long, Robert P Bejnarowicz and Bruce A SchoneboomAbstractIntroduction: The drugs gabapentin and ketamine are ... Discussion Cervical laminectomy and laminoplasty are routine neu-rosurgical procedures to treat myelopathy secondary t o cervical stenosis. According to some studies, cervical laminoplasty has over an...
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Báo cáo y học: "Altered mental status, an unusual manifestation of early disseminated Lyme disease: A case repor" pdf

... purposes)Journal of Medical Case ReportsOpen Access Case reportAltered mental status, an unusual manifestation of early disseminated Lyme disease: A case reportShiven B Chabria* and Jock LawrasonAddress: ... Alternatively, there may have beenantecedent erythema migrans and/or systemic complaintsin the early localized phase. Early disseminated Lyme dis-ease can have many central nervous system manifesta-tions. ... New Hampshire, Rhode Island, NewYork, New Jersey, Pennsylvania, Delaware, Maryland,Michigan, and Wisconsin [2]. The clinical manifestationsare usually categorized into early localized, early...
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Báo cáo y học: " Incisional hernia as an unusual cause of hepatic encephalopathy in a 62-year-old man with cirrhosis: a case repor" ppsx

... herniorrhaphy in such patients should be made after evaluating thepossible benefits and risks of the surgery.AbbreviationsALT, alanine aminotransferase; AST, aspartate aminotrans-ferase; HE, hepatic ... 115 mg/dl,creatinine 0.7 mg/dl, a lkaline phosphatase 220 U/L, aspartateaminotransferase (AST) 18 U /L, alanine aminotransferase(ALT) 30 U /l, g-glutamyl transpeptidase 20 U/l, total bilirubi ... patients, patients with increasedserum bilirubin and alkaline phosphatase levels.Abdominal wall hernias are commonly seen in patients with cirrhosis and ascites [11,12]. The main causativefactors...
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Báo cáo y học: " Multiple cysticerci as an unusual cause of mesenteric lymph node enlargement: a case report" ppsx

... human has been found in a search of the literature. This was the case of a 7-year-oldgirl who presented with seizures and submandibular lymph node enlargement. Fine needle aspiration cytology of ... anecdotal case of congenital neurocysticercosisdue to transplacental transmission of cysticerci has alsobeen reported [6]. A bizarre case of infestation after drink-ing a mixture prepared from ... release substances that pro-voke an inflammatory response. Eventually the cysticerci calcify and can be seen on X-ray. The organs most com-monly affected by cysticercosis are the eye (13% to...
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Báo cáo y học: " Tongue metastasis as an initial presentation of renal cell carcinoma: a case report and literature review" pps

... renal cell carcinomasmetastasize to the head and neck region – specifically, tothe paranasal sinuses, larynx, jaws, temporal bones, thy-roid gland, and parotid glands [3,4]. Tongue metastasis ... tongue mobility was normal and there was no palpable cervicallymphadenopathy.Systematic examination of chest, abdomen and heart werenormal. The lesion was biopsied and initially reported as a ... squamous cell carci-noma with clear cell changes, metastatic salivary glandneoplasm or metastases from RCC. It was decided toarrange an urgent CT scan and to debulk the tongue lesionsurgically,...
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Báo cáo y học:

Báo cáo y học: " Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice" ppt

... targetfor therapeutic intervention in RA. We therefore exam-ined the effects of endothelin receptor antagonists on the inflammation and inflammatory pain during the course of murine antigen-induced ... Imhof et al.: Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice. Arthritis Research & Therapy 2011 13:R97.Submit your ... of 9 any detectable anti-inflammatory or antinociceptive activity. Effect of bosentan on antigen-induced arthritis flare-upreactionsGiven the potent anti-inflammatory and antinociceptive activity...
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Báo cáo y học: "Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients" pps

... 25(OH )D 3: 25-hydroxy vitamin D3 ; 1a,25(OH)2 D 3: 1,25-dihydroxy vitamin D3 .AcknowledgementsWe would like to acknowledge the role of Goce Dimeski and the laboratorystaff in the Department of Chemical ... our findingsTo our knowledge this is the first study to examine the effects of volume loading on serum vitamin D concen-trations. Our data clearly demonstrate the impact of fluid loading on serum ... blood by the Vitamin D binding protein(VDBP) to the liver where it undergoes 25 hydroxylationto form 25(OH )D 3,which in turn undergoes 1a hydro-xylation (especially, but not exclusively in the...
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Báo cáo y học:

Báo cáo y học: " Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systemic review and meta-analysis" pps

... purpose has been debated and is not yetroutinely clinically performed. To adequately evaluate this assay, a systematic review and meta-analysis of studies ofthe CSF lactate concentration as a marker ... diagnostic accuracy of CSF lactate for the differ-ential diagnosis of BM from AM has varied across studies[11,12]. To adequately evaluate its accuracy, a syste matic review and meta-analysis ... (data not shown).Sub meta-analysis of lactate as a differential marker fordiagnosed BM from diagnosed viral AMMeta-analysis was further performed to assess the diag-nostic accuracy of lactate...
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