Báo cáo y học: " The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells" potx
Báo cáo y học: " The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells" potx
... sensing receptor (CaSR) is ex pressed in pulmonary artery smooth muscle cells (PASMCs ) and homogenates of pulmonary arteries (PAs). A. Detection of CaSR mRNA by RT-PCR in rat PASMCs in the absence ... CQ: Involvement of calcium-sensing receptor in cardiachypertrophy-induced by angiotensin II through calcineurin pathway in cultured neonatal rat cardiomyocytes. Biochem Biophys Res Commun 2008,369:584-589.12. ... as: Li et al.: The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells.Journal of Biomedical Science 2011 18:16.Submit your next manuscript...
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Báo cáo y học: "The functional spectrum of low-frequency coding variation" pot
... asexplained in the SNP calling methods.Base quality recalibration The base qualities reportedby the instrument were recalibrated using GATK asexplained in the SNP calling methods.INDEL calling INDELs ... 1, in order to remove the high number of false posi-tive INDELs in this category.Broad Institute Illumina INDEL calling pipelineRead mapping The BI Illumina INDEL calling pipelineused the ... validation rate. Coding INDEL variants change the amino acid sequence of the gene, and thereforethese variants are very likely to impact protein function.Indeed, the majority of the events...
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Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"
... quality improvement asa distinct career pathway. Involving such physicians in medicalemergency teams will likely facilitate the dual roles of these as aclinical outreach arm of the intensive ... substantial investments of time and money. Moreover,especially in the case of chart review, missing information oftenlimits the ability of reviewers to identify adverse events or judgetheir preventability. ... teams, mayprovide just such a method. The rationale for the development of METs rose from observations that, in the majority of patients, premonitory signs and symptoms of cardio- pulmonary instability...
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... toantipsychotics. In this case, fluvoxamine monotherapywas effective in the treatment of psychotic major depres-sion, and the switch to sertraline worsened the psychoticsymptoms in the patient. The ... psychopharma-cology from that of other SSRIs [29]. It is thereforepossible that activation of the dopaminergic system by the inhibition of dopamine transporter may be involved in the mechanism of unwanted effects ... Rady A, Kingsbury SJ, Fayek M: Sertraline as monotherapy in the treatment of psychotic and nonpsychotic depression. J Clin Psychiatry 2003, 64:959-965.10. Stahl SM: Antidepressant treatment of...
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Báo cáo y học: " The contrasting roles of PPARδ and PPARg in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue" ppt
... the integration of the energy metabolism pathways of 3T3-L1adipocytes. A diagram showing the effect of PPARg activation on the integration of the energy metabolism pathways of 3T3-L1 adipocytesbased ... observed by the increase in the creatine concentration within 3T3-L1 adipocytes treatedwith the PPARδ agonist, demonstrating an alteration to the high energy phosphate buffering capacity of the cells. ... also increased the TCA cyc le rate, as ind i-cated by following the labeling patterns induced by 1-13C glucose, the increased labeling of TCA cycle inter-mediates during metabolism of U-13C...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... replaced by the STAT1 recruiting motif of the interferon-c receptor result-ing in a chimeric protein designated gp130c.Inordertoinvestigate the role of the membrane-proximal domains of gp130 in receptor ... epitopes of both receptors. Deletion of a single domain in the membrane-proximal part of gp130leads to a shift of the receptor areas involved in ligandbinding closer to the membrane, resulting in the ... spacingbetween the CBM and the membrane, each of the domainswas replaced by the corresponding domain of the GCSFR. The replacement is assumed to compensate for the shift of the ligand-binding...
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Báo cáo sinh học: "The functional landscape of mouse gene expression" pdf
... were inferior (dottedmagenta line in Figure 6a). In theory, if any combination of on/off information about gene expression in differenttissues was informative for identifying genes in any cate-gory, ... discriminant values above the given dis-criminant value really are in the category in question. The proportion of known genes in the category that are identi-fied by the SVM as being in the category ... section) [29]. These provided further independentsupport for many of the predictions, since neither the primarysequences nor the domain features of the unannotated genesplayed a part in the predictions....
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Báo cáo y học: "The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanase" docx
... of the drugon the regulation of 5-LOX, one of the main enzymes involved in the synthesis of LTB4 by chondrocytes [4,24].Figure 2Cathepsin K gene expression and protein synthesisCathepsin ... simultaneously reducing the synthesis of LTB4 and IL-1β by the OA synovium [6]. Thesefindings are in strong support of the in situ role played by LTB4 in the structural changes that occur in OA. The ... however, the capacity of licofelone to inhibit the synthesis of IL-1β [6-8] may explain, at least in part, the effect of the drug on the synthesis of cathepsin K.Figure 3ADAMTS-5 gene expression...
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Báo cáo y học: "tatin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis" pptx
... immunomod-ulatory potential in RA [24]. Recognizing the preliminary nature of the clinical data supporting a disease-modifying effect forstatins in RA and the need for in vivo confirmation of our find-ings, ... decay-accelerating factor expressionHypoxia increases atorvastatin-induced decay-accelerating factor expression. Analysis of decay-accelerating factor expression on human umbilical vein endothelial ... CD59 inhibits the terminal pathway of complement acti-vation, preventing the incorporation of C9 into the MAC [18].While DAF expression is increased in the rheumatoid syn-ovium [10], expression...
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Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx
... aligned in a disorganisedmanner, which may contribute to the under-mineralisation in OA [8]. Interestingly, the findings of the present study indi-cated that the ratio of COL1A1/COL1A2 mRNA expression was ... subsequentlyaccumulated in the mineralised matrix. Increased OPN mayaugment OB synthetic activity by increasing OB longevity andsurface extent of bone formation. Hence, increased OPNmRNA expression in OA may contribute ... purposes)lular matrix, is synthesised only by bone-forming OB cells.OCN is suggested to be involved in the mineralisation process of newly synthesised osteoid [33]. It is incorporated into the bone matrix,...
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Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ